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Janina Werner

@janinawern.bsky.social
45 followers 57 following 3 posts

Postdoc @ Doehlemann lab 🍄 University of Cologne

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Reposted by Janina Werner
Maurice König @maukoe.bsky.social · 21/09/2026
Very happy to see our Zip1 work highlighted in Plant Physiology 🌽 Sequential proteolysis across compartments can shape where, when and in which form peptide signals act. Thanks to @mamoonakhan.bsky.social for the insightful highlight! academic.oup.com/plphys/artic...
academic.oup.com
A tale of 2 realms: spatial processing of the maize phytocytokine Zip1
Plants rely on sophisticated cell-to-cell communication to perceive environmental changes and coordinate appropriate responses. Among the signalling molecu
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Isabel saur @izzysaurlab.bsky.social · 17/09/2026
@madfungi.bsky.social (For5682) Retreat in beautiful Bad Breisig! great get together, great talks and science, super useful discussions with @algazuccaro.bsky.social @teamthomma.bsky.social @effectomics.bsky.social, Döhlemann and Requena and Hensel teams. Cool stuff and great Progress in sight!
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MadFungi @madfungi.bsky.social · 18/09/2026
A valuable and inspiring two-day retreat of the MadFungi research group in Bad Breisig. The retreat provided a great opportunity to step back from our daily work, exchange ideas, reflect on our research, and strengthen collaboration within the group. 🍄
MadFungi Retreat 2026 - Bad Breisig
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Maurice König @maukoe.bsky.social · 11/08/2026
Very happy to share our new paper in Plant Physiology! 🌽 We uncover a 2-step mechanism controlling maize phytocytokine Zip1: ZmMC9 processes PROZIP1 intracellularly, enabling export of bioactive Ct-PROZIP1, while apoplastic proteases attenuate the signal. doi.org/10.1093/plph...
Schematic model of the two-step processing and regulation of the maize phytocytokine PROZIP1/Zip1. Intracellularly, PROZIP1 associates with the ER and is cleaved by the Ca²⁺-dependent type II metacaspase ZmMC9, generating the C-terminal fragment Ct-PROZIP1. This bioactive fragment is exported to the apoplast through a Golgi-independent route, where it activates immune signaling. In a second step, apoplastic proteases, including the papain-like cysteine proteases CP1 and CP2, further process and degrade Ct-PROZIP1 and Zip1, thereby attenuating and clearing the signal.
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Team_Zuccaro @algazuccaro.bsky.social · 20/05/2026
Proud to share our new paper on how prion-like fungal effectors target plastids and modulate host metabolism during root symbiosis. Exciting collaborative work uncovering PEPSI effectors and the interaction of one of them with DXR in plants. www.biorxiv.org/content/10.6... bsky.app/profile/eell...
biorxiv.org
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Maurice König @maukoe.bsky.social · 15/05/2026
One highlight from our review: peptide signals can be copied or rerouted to redirect plant responses. 🌱 Bacteria, fungi and nematodes tap into phytocytokine pathways via mimics or altered release - steering infection, colonization and symbiosis. Read more about it here: doi.org/10.1111/tpj....
doi.org
Processing and release of endogenous immunogenic peptide signals
Plant endogenous peptides, termed phytocytokines, coordinate immune responses and mediate intercellular communication within and across plant tissues. While an expanding repertoire of ligands, recept...
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Reposted by Janina Werner
Maurice König @maukoe.bsky.social · 11/05/2026
Plants use immunogenic peptides to coordinate immunity. Pathogens can mimic them to hijack defense. 🌱 We compare phytocytokines with animal cytokines and ask how these signals are made, released, mimicked, and controlled in space and time. doi.org/10.1111/tpj....
Conceptual comparison of animal cytokine and plant phytocytokine signaling ranges, from cell-autonomous/local action to systemic communication.
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Team Thomma @teamthomma.bsky.social · 30/04/2026
Where do plant pathogen effectors come from? @mesny.bsky.social shows how fungi turned shield 🛡️ into sword ⚔️ to end up with dual-function molecules to disrupt host immunity & protective host microbiota. @ceplas.bsky.social @mibinet.bsky.social @madfungi.bsky.social www.science.org/doi/10.1126/...
science.org
Plant-associated fungi co-opt ancient antimicrobials for host manipulation
Fungal effectors may have evolved from ancient antimicrobials, shaping plant microbiota and immunity during infection.
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MadFungi @madfungi.bsky.social · 30/04/2026
Thank you to @izzysaurlab.bsky.social, @teamthomma.bsky.social, and their teams for hosting our next two MadFungi workshops, "Expression in Barley Protoplasts" and "Expression of Antimicrobial Proteins," at @unicologne.bsky.social. It was a great week with all of our MadFungi PhD candidates! 🍄
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Eva Stukenbrock @estukenbrock.bsky.social · 13/04/2026
So diverse and yet conserved. Check out opinion paper by Leonhard Pachinger @leopach.bsky.social on antimicrobial effectors produced by fungal pathogens: www.sciencedirect.com/science/arti...
sciencedirect.com
Antimicrobial effectors of plant-associated fungi: multipurpose proteins with fast-evolving surfaces and structurally conserved cores
Plants are exposed to a variety of devastating pathogens, causing significant yearly yield losses. In order to facilitate infections, plant pathogens …
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Team_Zuccaro @algazuccaro.bsky.social · 17/04/2026
Very proud to share our new paper led by Mathias Brands from my team at @UniCologne! With Markus Pauly team @HHU. Host-adapted enzymatic deconstruction of acetylated xylan limits immune activation and facilitates mutualistic colonization of monocot roots: Molecular Plant www.cell.com/molecular-pl...
cell.com
Host-adapted enzymatic deconstruction of acetylated xylan limits immune activation and facilitates mutualistic colonization of monocot roots
This study identifies a monocot-specific enzymatic module in the beneficial root endophyte Serendipita indica, showing how ancestral saprotrophic enzymes have been repurposed into an immune-compatible...
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Janina Werner @janinawern.bsky.social · 27/03/2026
Check out our new preprint ☺️⏬️
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Wei Shi @wshisky.bsky.social · 10/01/2026
Huge thanks to my amazing co-authors, to AG Saur and AG Döhlemann, and to all our collaborators for their fantastic contributions @Merle Bilstein-Schloemer@izzysaurlab.bsky.social @grandpahiro.bsky.social @sara-stolze.bsky.social@Gunther Döhlemann@Matthieu Pierre Platre ! 🙏
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MadFungi @madfungi.bsky.social · 23/09/2025
Our PhD candidates are having a great time at the MadFungi transcriptomics workshop at the University of Kiel @uni-kiel.de. Special thanks to @estukenbrock.bsky.social and her team for the great organization!
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Isabel saur @izzysaurlab.bsky.social · 05/09/2025
I am thrilled &honoured, what a journey that was! Only possible with the great support from family, all lab members, friends, current @unicologne.bsky.social / @ceplas.bsky.social & former colleagues & mentors. With this project, we will do all that we can to help protect plants from diseases (1/2)
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Johana Misas Villamil @jomivi.bsky.social · 18/06/2025
Happy to share our last preprint where we discovered a two step mechanism for the release of the maize signaling peptide Zip1. A “two - factor authentication”. Enjoy the reading! 👇
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bioRxiv Plant Bio @biorxiv-plants.bsky.social · 17/06/2025
Processing and release of the maize phytocytokine Zip1 www.biorxiv.org/content/10.1101/202…
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Janina Werner @janinawern.bsky.social · 15/06/2025
Happy to share our work on a recombinant interspecific smut hybrid of two fungal maize pathogens which helped us to understand how the regulation of effector genes determines infection style and tumor formation. Thanks to Gunther Doehlemann, Weiliang Zuo & Tom Winkler! www.cell.com/cell-reports...
cell.com
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Johana Misas Villamil @jomivi.bsky.social · 06/04/2025
Check this out👇 New from the Doehlemann lab! A fungal enzyme modulates plant-microbe and microbe-microbe interactions 🔥
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Isabel saur @izzysaurlab.bsky.social · 20/02/2025
This was a truely fantastic day with great speakers. Thx to the organisers at the IfP @unicologne.bsky.social, @ceplas.bsky.social and the @trr341.bsky.social & of course all speaker. Cu next year on 19.02. for the next symposium
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MadFungi @madfungi.bsky.social · 07/02/2025
The MadFungi🍄 research unit funded by @dfg.de kicked off this week with our meeting in Cologne @unicologne.bsky.social. We're excited to see what great science we'll achieve over the next four years.
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Isabel saur @izzysaurlab.bsky.social · 05/02/2025
Gunther Döhlemann starting the MadFungi research unit (for5682.uni-koeln.de) kick off meeting involving groups from @hhu.bsky.social, @unibonn.bsky.social @uni-kiel.de, @kit.edu and of course @unicologne.bsky.social (eg. @teamthomma.bsky.social, @algazuccaro.bsky.social ). Let‘s go
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