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James R Evans

@jamesrevans.bsky.social

Postdoctoral research fellow at UCL Queen Square Institute of Neurology and the Francis Crick Institute. Former musician.

Posts Replies Media

Reposted by James R Evans

Aligning Science Across Parkinson's @asapresearch.parkinsonsroadmap.org · 05/06/2026

How do immune and genetic drivers shape vulnerability in #ParkinsonsDisease? 🧠 Discovery Fellows M. Elizabeth Deerhake, James Evans, Amandine Even, Alexandra Kazanova, and Indrani Poddar are linking inflammation, genomics, and systemic factors to disease progression ⬇️ 🔗 bit.ly/3P9uqCM

Graphic with a purple-to-blue gradient background titled “Neuroinflammation, Genomic Regulation, and Systemic Drivers.” Subheading: “Understanding how systemic and genetic drivers fuel inflammation to unlock immune-targeted and precision approaches.” Below are five circular headshots of researchers in the CRN Discovery Fellowship with their affiliations: M. Elizabeth Deerhake, MD, PhD (Home: Team Hafler; Host: Team Scherzer); James Evans, PhD (Home: Team Wood; Host: Team Studer); Amandine Even, PhD (Home: Team Desjardins; Host: Team Schapira); Alexandra Kazanova, PhD (Home: Team Desjardins; Host: Team Sulzer); and Indrani Poddar, PhD (Home: Team Lee; Host: Team Studer)

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Reposted by James R Evans

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 09/09/2025

TDP-43 loss of function drives aberrant splicing in Parkinson's disease www.biorxiv.org/content/10.1101/202…

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James R Evans @jamesrevans.bsky.social · 01/09/2025

Out now on biorxiv! Excited to share our latest collaborative work investigating the earliest stages of Parkinson’s disease. www.biorxiv.org/content/10.1... Thanks to all the amazing co-authors Melissa Grant-Peters @jsbeckwith.bsky.social @stevethechemist.bsky.social Mina Ryten Sonia Gandhi

biorxiv.org

Microglial activation and alpha-synuclein oligomers drive the early inflammatory phase of Parkinson's disease

Parkinson's disease (PD) is characterised by insoluble α-synuclein (αSyn) aggregates in Lewy bodies (LBs) within the substantia nigra, with cortical pathology appearing as the disease progresses. Late...

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Reposted by James R Evans

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 28/08/2025

Microglial activation and alpha-synuclein oligomers drive the early inflammatory phase of Parkinson's disease www.biorxiv.org/content/10.1101/202…

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