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jacolm.bsky.social

@jacolm.bsky.social
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Disease Transcriptomics (NMorais) Lab @nmoraislab.bsky.social · 14/09/2026
New preprint 📣! We reanalysed stress granule transcriptomes and found differential centrifugation is strongly biased by RNA length. Correcting for this erases most reported overlap. Mitochondrial RNAs remain as a modest signal, hinting at immune signalling. doi.org/10.64898/202...
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Disease Transcriptomics (NMorais) Lab @nmoraislab.bsky.social · 07/08/2026
Garbage In, Plot Out 🧠 A bioinformatics pipeline will always give you something: a plot, a p-value, a cluster. It won’t tell you whether the parameters you chose were the right ones. That’s the black box problem in bioinformatics 📊. A thread on why critical thinking matters 🧵
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Disease Transcriptomics (NMorais) Lab @nmoraislab.bsky.social · 24/07/2026
🚀 Our new research lab website is now live! After a few months of moving, settling in, and rebuilding, the Disease Transcriptomics Lab is now online: diseasetranscriptomicslab.github.io Find out more about our research, tools, people, ethos, and opportunities to join us.
diseasetranscriptomicslab.github.io
Disease Transcriptomics Lab · NMorais Lab
Decoding transcriptomes to understand disease. Computational biology research at NOVA Medical School, Lisbon.
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Disease Transcriptomics (NMorais) Lab @nmoraislab.bsky.social · 08/06/2026
Finally out, a much improved peer-reviewed article published in NAR Genomics & Bioinformatics @academic.oup.com. 👏 @ritamtbs.bsky.social and @a-kaizeler.bsky.social! academic.oup.com/nargab/artic...
academic.oup.com
Exploring molecular signatures of senescence with marker, an R Toolkit for evaluating gene sets as phenotypic markers
Abstract. Many biological processes, including cellular senescence, manifest as diverse phenotypes across cell types and conditions. Lacking definitive mar
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Disease Transcriptomics (NMorais) Lab @nmoraislab.bsky.social · 06/02/2026
On World Cancer Day, Francisca's PhD project was awarded an Oncology Research Grant by the Portuguese League Against Cancer (Southern Regional Center) and the Benfica Foundation, to support her work on testing predictive biomarkers of therapeutic response in rectal cancer. 🙏🦀⚕️💪
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Disease Transcriptomics (NMorais) Lab @nmoraislab.bsky.social · 30/01/2026
We are proud of the Lab's participation in the CAML & GIMM PhD Meeting this week: @a-kaizeler.bsky.social, @ritamtbs.bsky.social and Francisca eloquently presented their work to their colleagues 👏. @ritamtbs.bsky.social won the award for Best Poster Presentation by a 4th year PhD student! 🥇
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Disease Transcriptomics (NMorais) Lab @nmoraislab.bsky.social · 11/12/2025
Following the @bioconductor.bsky.social package, the @biorxivpreprint.bsky.social preprint: "Exploring molecular signatures of senescence with markeR, an R toolkit for evaluating gene sets as phenotypic markers". 💻🧬📰 👏 @ritamtbs.bsky.social 💪 www.biorxiv.org/content/10.6...
biorxiv.org
Exploring molecular signatures of senescence with markeR, an R toolkit for evaluating gene sets as phenotypic markers
Many biological processes, including cellular senescence, manifest as diverse phenotypes that vary across cell types and conditions. In the absence of single, definitive markers, researchers often rel...
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Disease Transcriptomics (NMorais) Lab @nmoraislab.bsky.social · 28/11/2025
Our Maria successfully defended her MSc dissertation on Tuesday afternoon and still found the energy to present her work on the isoform-specific impact of mutations in CDKN2A in cancer again the following morning, at the 9th Annual Conference of ULisboa redeSAÚDE. 💻🧬 👏🍾 💪
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Disease Transcriptomics (NMorais) Lab @nmoraislab.bsky.social · 19/11/2025
Front row view of our Maria smoothly presenting her MSc dissertation work on the isoform-specific impact of mutations in CDKN2A in cancer at the Oncobiology Club @gimmfoundation.bsky.social. 💻🧬👏
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Disease Transcriptomics (NMorais) Lab @nmoraislab.bsky.social · 18/11/2025
Do you want to know more on what the PhD with us is about? 🙂 We are still looking for the perfect candidate! 🔎 Please spread the word! 🙏
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EVOMG-Doctoral Network @evomg-dn.bsky.social · 16/10/2025
Become part of a Marie Skłodowska-Curie Doctoral Network a prestigious EU initiative offering world-class research training, international experience, and strong career prospects for early-stage researchers. It’s more than a PhD:it’s a launchpad for your research career! Apply now: www.evomg-dn.eu
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Disease Transcriptomics (NMorais) Lab @nmoraislab.bsky.social · 07/10/2025
Did we mention that we would like you to do a PhD with us? 😉
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BIOMICS_GIMM @biomics-twinning.bsky.social · 04/07/2025
Check this out!!! A PhD student from our project’s coordinator lab @nmoraislab.bsky.social has developed an R package - markeR. Kudos to @ritamtbs.bsky.social 👏👏 Well done!!!
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Disease Transcriptomics (NMorais) Lab @nmoraislab.bsky.social · 20/06/2025
Kudos to Daniel for the outstanding development of an approach to identify actigraphy-based markers of split shift work in submariners in a smooth interdisciplinary collaboration with Cátia Reis @gimmfoundation.bsky.social . ☀️🌒💪 Feedback is most welcome! 🙂 www.biorxiv.org/content/10.1...
biorxiv.org
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Disease Transcriptomics (NMorais) Lab @nmoraislab.bsky.social · 17/06/2025
Alex is representing the Lab at #EACR2025 @helloeacr.bsky.social. 💪 If you are around today, you can have a sneak peek at his poster P-024 (on stress granules 🧐) from 10h45 and listen to Alex presenting it from 18h40. 👨‍🏫
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BIOMICS_GIMM @biomics-twinning.bsky.social · 23/04/2025
The BIOMICS website is now live! 🚀 An EU project connecting data science, training & innovation in health, led by @gimmfoundation.bsky.social with @crg.eu, @ebi.embl.org & @ethzurich.bsky.social. Discover more 👉 biomics.gimm.pt #BIOMICS #HorizonEU #DataScience #HealthInnovation
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Disease Transcriptomics (NMorais) Lab @nmoraislab.bsky.social · 08/05/2025
We proudly have a new Doctor! 🥳 Many congratulations, Mariana, for the brilliant viva yesterday! 👏🎓🍾 We wish you all the best for the future! ❤️ Thank you, @edueyras.bsky.social, @biocomicslab.bsky.social, @mgama.bsky.social, Leonor Saúde, and Mário Ramirez for the fantastic discussions! 🙏
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Disease Transcriptomics (NMorais) Lab @nmoraislab.bsky.social · 24/04/2025
Kudos to our Marta for her tremendous work developing scStudio. 💪 If you are into scRNA-seq data analysis, have a look at the preprint, give the app a go, and please send us your feedback. 🙂 www.biorxiv.org/content/10.1...
biorxiv.org
scStudio: A User-Friendly Web Application Empowering Non-Computational Users with Intuitive scRNA-seq Data Analysis
Single-cell RNA sequencing (scRNA-seq) has revolutionized our understanding of cellular heterogeneity by providing detailed insights into gene expression at the individual cell level. Despite its pote...
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BIOMICS_GIMM @biomics-twinning.bsky.social · 23/01/2025
🗣️ Nuno Morais, BIOMICS Coordinator and Group Leader at GIMM @nmoraislab.bsky.social has launched the "Young Data Scientists Mini-Symposium" by presenting to BIOMICS early researchers the activities that will be implemented throughout the project and how they can benefit from them.
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BIOMICS_GIMM @biomics-twinning.bsky.social · 22/01/2025
🌟 BIOMICS Kick-Off Meeting Is Almost Here! 🌟 This exciting event will bring together 59 participants from our 4 partner institutes – @crg.eu, @ebi.embl.org, @ethzurich.bsky.social, and @gimmfoundation.bsky.social – along with members of our Advisory Boards. #BIOMICS #DataScience
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Disease Transcriptomics (NMorais) Lab @nmoraislab.bsky.social · 28/11/2024
We kick off our activity in Bluesky expressing our pride of Francisca and Jacek (@jacolm.bsky.social) for an excellent job yesterday, explaining machine learning approaches for biomarker discovery to oncobiologists at GIMM. 👏
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