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Jacob Pendergrast

@jacobpendergrast.bsky.social
85 followers 47 following 51 posts

Hematologist in Toronto, Canada

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Reposted by Jacob Pendergrast
Eric Topol @erictopol.bsky.social · 11/08/2026
Vaccine benefit in children "Since 1974, vaccination has averted 154 million deaths, including 146 million among children younger than 5 years of whom 101 million were infants younger than 1 year." www.thelancet.com/journals/lan... The most striking benefit was for vaccination vs measles (Figure)
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Jacob Pendergrast @jacobpendergrast.bsky.social · 19/06/2026
Today is World Sickle Cell Disease Awareness Day! To acknowledge, I recommend the following: 1. Type “Tell me the most important thing to know about sickle cell disease in [your city]” into google or your preferred AI 2. Spread the word!
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Jacob Pendergrast @jacobpendergrast.bsky.social · 22/05/2026
Jose de la Fuente showing data that has traditionally justified adult SCT in pts with sickle cell disease but not thalassemia — iron overload = GVHD = incr mortality. But does age become less reliable a surrogate marker for hemochromatosis in era of oral iron chelators?
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Jacob Pendergrast @jacobpendergrast.bsky.social · 21/05/2026
Haydar Frangoul presenting on curative therapies for sickle cell disease, often performed in adults, makes a striking statement: these are patients who have been “sick” their entire lives. When they are suddenly free of disease, many are left wondering what to do with their lives, may feel lost
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Jacob Pendergrast @jacobpendergrast.bsky.social · 24/03/2026
$11 000 per second. Read to see how this compares to the cost of spending elsewhere which has recently been cut for being "wasteful" (humanitarian aid, public broadcasting, paid parental and sick leave, child tax credits, school lunch programs) jacobin.com/2026/03/pent...
jacobin.com
The US Is Spending Billions to Bomb Iran
The Trump administration has spent around $24 billion in public funds on its war against Iran so far. Here’s what that money might have been used for instead.
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Jacob Pendergrast @jacobpendergrast.bsky.social · 06/02/2026
University of Toronto graduate and the latest member of the transfusion medicine community, Dr. Lianne Rotin. Welcome to the club ❤️
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Jacob Pendergrast @jacobpendergrast.bsky.social · 05/02/2026
Donating blood as part of the Sickle Cell Awareness Group of Ontario‘s collaboration with Canadian Blood Services. My own blood isn’t especially rare, but you have to walk it like you talk it when trying to encourage people to donate the first time. See? Easy!
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Reposted by Jacob Pendergrast
Our World in Data @ourworldindata.org · 15/12/2025
✍️We published a new topic page on medicine and biotechnology— For much of human history, people relied on trial and error to find cures for diseases and health conditions using natural plants and remedies, with little idea of which ingredients worked or why.
A timeline titled "The Golden Age of Antibiotics" shows when each antibiotic drug class was first available for medical use, with example antibiotics labeled. Classes are color-coded by their source: actinomycetes, other bacteria, fungi, or synthetic. Milestones include the first antibiotics (arsphenamines in 1910), as well as the discovery of many actinomycetes-derived antibiotics, such as streptomycin, and sulfonamides, penicillins, and tetracyclines. Data: Hutchings, Truman, Wilkinson (2019). Created by Saloni Dattani for Our World in Data.
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Reposted by Jacob Pendergrast
Danyaal Raza @danyaalraza.com · 24/11/2025
From the chair of the federal government’s National Pharmacare Committee of Experts, Nav Persaud does not mince his words. www.thestar.com/opinion/cont...
thestar.com
Here’s one thing Mark Carney could do that would improve the welfare of more Canadians than any pipeline or mine
Canada spends about $10 billion more on medicines each year than countries with universal pharmacare because our system doesn't provide access to medications through government-issued health cards.
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Reposted by Jacob Pendergrast
Blood Journals Portfolio @bloodjournals.hematology.org · 15/11/2025
Adults with SCD and parvovirus B19 infection showed 3 phenotypes: erythroblastopenia, BMN, and vaso-occlusive events. Patients with BMN had longer hospital stay but no differences in parvovirus B19 genotype or diversity across groups. Read here: buff.ly/dNk4xxo
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Jacob Pendergrast @jacobpendergrast.bsky.social · 24/10/2025
Join Dr. Linda Barnes, Ms. Caroline Wangamati, and me for an interesting discussion of innovations from the Blood D.E.S.E.R.T. Coalition #AABB2025
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Jacob Pendergrast @jacobpendergrast.bsky.social · 03/10/2025
Please read @cmadocs.bsky.social @rcphysicians.bsky.social
thelancet.com
Gaza's healthocide: medical societies must not stay silent
The catastrophic humanitarian crisis in Gaza, with the apparent deliberate targeting of health-care infrastructure and personnel, has highlighted a profound challenge to the global medical community. ...
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Jacob Pendergrast @jacobpendergrast.bsky.social · 21/08/2025
Speak up for National Pharmacare in Canada! Save lives! Save money! @juliedabrusin.bsky.social @mark-carney.bsky.social @cdndrsformedicare.bsky.social @canadahealthwatch.ca @uhn.ca @utoronto.ca @cma-acs.bsky.social
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Jacob Pendergrast @jacobpendergrast.bsky.social · 11/08/2025
www.thelancet.com/action/showP...
thelancet.com
The famines in Gaza and other conflict areas are a moral failure
As scientists and members of the Standing Together for Nutrition Consortium (ST4N) who have been Standing Together For Nutrition during recent crises, we use evidence of the impact of crises on nutrit...
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Jacob Pendergrast @jacobpendergrast.bsky.social · 19/07/2025
Action alert: The City of Toronto is considering restricting fossil fuel ads. These ads undermine climate action & put everyone at risk. We have a short window of time for the City Council to act. Take action here: cape.ca/action/ban-f...
cape.ca
Call on Toronto City Council to stop promoting fossil fuels - CAPE
Raise your voice and call on Toronto City Council to take a stronger stand against fossil fuel advertising.
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Jacob Pendergrast @jacobpendergrast.bsky.social · 10/07/2025
Save Canadian hemovigilance! We can't improve the safety of blood transfusion if we don't monitor the harms it causes! @canadahealthwatch.ca @cdnhealthcoalition.bsky.social @cmadocs.bsky.social @cstm-scmt.bsky.social chng.it/Ks2BHwWRLC
chng.it
Have you seen this petition yet?
#Fight4Hemovigilance: Save Canada's Blood Safety Contribution Program
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Jacob Pendergrast @jacobpendergrast.bsky.social · 04/07/2025
@utoronto.ca has produced another stellar transfusion medicine specialist: Dr Sheharyar Raza (@transfusion.health). Keep an eye on this one, he is destined for great things
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Canadian Society for Transfusion Medicine @cstm-scmt.bsky.social · 27/06/2025
Hemovigilance in Canada is under threat. We continue to add resources and links for advocacy - stay up to date with how you can help. www.transfusion.ca/hemovigilance
transfusion.ca
CSTM - Hemovigilance
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Jacob Pendergrast @jacobpendergrast.bsky.social · 27/06/2025
Coming back to a long-neglected manuscript is like going back to the gym after you’ve slacked off for the past few months… you dread it, you delay, you find excuses, but then when you actually do it, it’s such a relief and you feel so much better afterwards I need a publishing coach
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Reposted by Jacob Pendergrast
International Society of Blood Transfusion @isbt.bsky.social · 26/06/2025
Congrats to Karina Yazdanbakhsh on receiving the ASH Henry M. Stratton Medal for Basic Science! Her groundbreaking research in transfusion medicine and sickle cell disease is shaping the future of targeted therapies Proud to have her as Co-Chair of the Basic Transfusion Biology WP
nybce.org
NYBCE's KARINA YAZDANBAKHSH, PhD, HONORED WITH THE AMERICAN SOCIETY OF HEMATOLOGY (ASH) HENRY M. STRATTON MEDAL FOR BASIC SCIENCE
Award is among ASH’s highest honors, recognizing outstanding contributions to the field of hematology. Learn more.
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Reposted by Jacob Pendergrast
Geoffrey Barnes, MD, MSc @gbarnesmd.bsky.social · 25/06/2025
Many people wonder if the severity of an acute PE influences VTE recurrence risk and therefore should impact DOAC dose selection? A post-hoc analysis of RENOVE study shows similar rates or recurrent VTE based on PE severity. #ISTH2025
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Jacob Pendergrast @jacobpendergrast.bsky.social · 19/06/2025
June 19th is World Sickle Cell Awareness Day. Below is a link to a good review article on the subject, and in this thread are my two wishes as a physician who treats the condition: www.healthaffairs.org/content/fore...
healthaffairs.org
Beyond Gene Therapies: People With Sickle Cell Disease Need Comprehensive Care | Health Affairs Forefront
We can do better. We can build a system that provides coordinated high-quality care to every patient who needs it.
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Reposted by Jacob Pendergrast
Eric Topol @erictopol.bsky.social · 01/06/2025
The remarkable benefit of exercise was just extended to improved survival after cancer in a randomized trial @nejm.org nejm.org/doi/full/10....
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Jacob Pendergrast @jacobpendergrast.bsky.social · 31/05/2025
Dr. Natasha Pardy making a passionate argument that patients in rural and remote communities are entitled to the same quality of health care as those in cities -- following equally persuasive presentations by Coleen Moores (hemophilia nurse) and Leonard Duffenais (patient) @cstm-scmt.bsky.social 2025
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Jacob Pendergrast @jacobpendergrast.bsky.social · 31/05/2025
Dr. Yoelys Cruz Leal presenting her CBS Dana Devine Award Lecture the @cstm-scmt.bsky.social 2025 Annual Meeting on her research distinguishing trogocytosis from phagocytosis. Her focus was on RhIg prophylaxis, but her discoveries may also one day reveal a way to safely transfuse incompatible RBCs
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Reposted by Jacob Pendergrast
University Health Network @uhn.ca · 30/05/2025
"There is a cohort of talent unlike we have ever seen before that we can compete for." Dr. @bradwouters.com, EVP of Science & Research at UHN, gives CBC's The National an inside look at Canada Leads, an initiative to recruit 100 top early-career scientists.
cbc.ca
How Canada is trying to tap America’s brain drain
There’s a global rush to recruit America’s top talent as Trump administration policies push many professionals to explore career and study plans abroad. CBC’s Eli Glasner takes a closer look at effort...
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Jacob Pendergrast @jacobpendergrast.bsky.social · 31/05/2025
Stacey Greeley presenting her Buchanan Award Lecture at the @cstm-scmt.bsky.social Annual Meeting. She joked that the audience might struggle with her Newfoundland brogue, but we understood perfectly as she described the rewards and challenges of providing transfusion support to rural hospitals
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Jacob Pendergrast @jacobpendergrast.bsky.social · 31/05/2025
Dr. William Sheffield giving his QuidelOrtho award speech at the 2025 annual @cstm-scmt.bsky.social meeting. He reviewed his career focus on serpins, plasma and albumin, work that has done much to advance the fields of transfusion medicine and hemostasis. Funny, humble and very impressive 👏
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Reposted by Jacob Pendergrast
Canada Healthwatch 🍁 @canadahealthwatch.ca · 29/05/2025
American doctors look to relocate to Canada to avoid the Trump administration www.npr.org/sections/sho... @npr.org 𝗠𝗼𝗿𝗲 𝗵𝗲𝗮𝗹𝘁𝗵 𝗻𝗲𝘄𝘀 ⇢ CanadaHealthwatch.ca 🍁
illustration of sad American doctors crossing the border into Canada
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Raza @transfusion.health · 03/05/2025
Can we rationalize the way we give diuretic prophylaxis before transfusion? Colleagues @uhntoronto.bsky.social incl talented co-fellow Dr. Rotin and @jacobpendergrast.bsky.social have made a substantial stride in dose modelling to target urine output onlinelibrary.wiley.com/doi/pdf/10.1... #medsky
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Jacob Pendergrast @jacobpendergrast.bsky.social · 08/05/2025
Was orienting a PGY2 to my clinic, chatting as I always do in a collegial, informal manner, and at the end, he says “Dr. Pendergrast , I just wanted to mention: you trained my Dad!” He showed me a picture of someone who is now an established transplant nephrologist #feelingold
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Jacob Pendergrast @jacobpendergrast.bsky.social · 01/05/2025
This was a fun interview :-) Reminiscing on residency: Dr. Jacob Pendergrast canadianhealthcarenetwork.ca/reminiscing-...
canadianhealthcarenetwork.ca
Reminiscing on residency: Dr. Jacob Pendergrast
For this series, we’re looking to talk to doctors from all walks of medicine—asking them how they got to where they are today and what their best advice is for those MDs just reaching the intensity of...
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Jacob Pendergrast @jacobpendergrast.bsky.social · 03/04/2025
Do your homework, but you will find you can make a very good living here, largely free from the moral injury of having to deny care to the uninsured, and in an environment where research and academic inquiry are respected and funded.
thestar.com
Surge of U.S. doctors looking to Canada amid Trump turmoil
Interest from American doctors considering work in Canada has increased by 63 per cent.
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Jacob Pendergrast @jacobpendergrast.bsky.social · 03/04/2025
www.counterpunch.org/2025/03/10/w...
counterpunch.org
Why US Automakers Make Vehicles and Source Parts in Canada
President Trump is blowing up the global economy with threats of extortionate tariffs being placed on imports from foreign countries to the US. He sometimes makes the ludicrous claim as in the case of...
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Jacob Pendergrast @jacobpendergrast.bsky.social · 02/04/2025
www.thestar.com/business/can...
thestar.com
Canada’s tainted blood scandal warned against paying donors for blood products. So why are paid-plasma clinics popping up across the country?
Canadian Blood Services’ partnership with a private company that pays for plasma puts the ethics and safety of our blood system at risk, critics say.
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Reposted by Jacob Pendergrast
American Society of Hematology @ash.hematology.org · 01/04/2025
ASH decries HHS restructuring and CDC layoffs. The Blood Disorders Division addresses SCD, thrombosis, hemophilia, thalassemia, and more. Millions' health is at stake; ASH urges immediate action. #Fight4Hematology #HemeSky #MedSky
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Canada Healthwatch 🍁 @canadahealthwatch.ca · 02/04/2025
‘100 calls per month’: Why U.S. doctors are looking to move to Canada globalnews.ca/news/1110905... @kdangerfield.bsky.social 𝗚𝗲𝘁 𝘄𝗲𝗲𝗸𝗹𝘆 𝘂𝗽𝗱𝗮𝘁𝗲𝘀: CanadaHealthwatch.ca/newsletter 🍁
odd photo of a doctor wearing blue nitrile gloves and holding up a novelty medical mask with a Canadian flag printed on it in a manner that obstructs her face from the nose-down
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Ben Collins @bencollins.bsky.social · 27/03/2025
They are just disappearing people off the street. Having a hard time thinking about literally anything else.
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American Society of Hematology @ash.hematology.org · 07/03/2025
📢 ASH stands up for science! 🩸🧪🔬 Today, ASH joined fellow advocates at the @standupforscience.bsky.social rally to support continued investment in scientific research and innovation. Let’s protect the future of #medicine, #research, and #patientcare together! 🙌💉 #Hematology #Hemesky #Medsky
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American Society of Hematology @ash.hematology.org · 07/03/2025
Because 👏 science 👏saves 👏 lives👏 Amazing to see everyone come together today at the @standupforscience.bsky.social rally! ASH is here to protect science and advocate for the funding and support that drives innovation in #hematology and beyond. 💪🩸
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Jacob Pendergrast @jacobpendergrast.bsky.social · 08/03/2025
Incredible synergies result when blood suppliers and sickle cell advocacy groups team up — each side needs the support of the other to achieve the common goal of safe and effective transfusion therapy. Thank you CBS and SCAGO for hosting a fantastic evening 🇨🇦
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Jacob Pendergrast @jacobpendergrast.bsky.social · 06/03/2025
Ever wanted to know the ins and outs of putting together a research team? Join us on March 20th! www.transfusion.ca/Events/Canad...
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Katharine Hayhoe @katharinehayhoe.com · 28/02/2025
Immigration, Refugees, and Citizenship Canada adds Education, expands Healthcare, and retains STEM occupations in its 2025 Express Entry categories. More:
cicnews.com
BREAKING: Canada announces major changes to Express Entry categories
Immigration, Refugees, and Citizenship Canada (IRCC) has announced the 2025 Express Entry categories on February 27, 2025. The department introduced big changes to category-based draws, introducing a ...
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Atul Gawande @agawande.bsky.social · 27/02/2025
Rubio terminated 5800 USAID contracts – more than 90% of its foreign aid programs – in defiance of the courts. Here’s a list of just some of the lifesaving awards that were terminated. Nearly all were Congressionally mandated. They’ve saved millions of lives. 🧵
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University Health Network @uhn.ca · 26/02/2025
UHN, Canada’s top hospital, is ranked third in the world for the second year in a row by @newsweek.com! This 2025 ranking solidifies UHN’s Toronto General Hospital as the top publicly-funded hospital in the world. Read the full report here: www.newsweek.com/rankings/wor...
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Jacob Pendergrast @jacobpendergrast.bsky.social · 26/02/2025
An inspiring evening hosted by @uhntoronto.bsky.social honouring the Princess Margaret Hospital hall-of-fame inductees: Gary Rodin, David Mccready, Armand Keating, Donna Reece, Patrick Gullane, Steven Gallinger, Bernard Cummings, and Frances Shepherd
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Canada Healthwatch 🍁 @canadahealthwatch.ca · 25/02/2025
Canada lures US doctors amid authoritarian shift canadahealthwatch.ca/newsletter/2... @nicktsergas.ca 𝗚𝗲𝘁 𝘄𝗲𝗲𝗸𝗹𝘆 𝘂𝗽𝗱𝗮𝘁𝗲𝘀: CanadaHealthwatch.ca/newsletter 🍁
canadahealthwatch.ca
Canada lures US doctors amid authoritarian shift
US doctors are looking to leave an environment that’s become unstable and frankly, scary.
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Robb Barnes 🇨🇦 @robb-barnes.bsky.social · 08/02/2025
We shouldn’t mince words. Trump’s gutting of USAID will leave some of the world’s poorest to die in agony. Those responsible are some of the world’s richest. www.nytimes.com/2025/02/08/w...
nytimes.com
Trump and Musk Bring Vast Aid Machinery to a Halt in Africa
The collapse of U.S.A.I.D. at the hands of President Trump and Elon Musk is already leaving gaping holes in vital health care and other services that millions of Africans rely on for their survival.
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Jacob Pendergrast @jacobpendergrast.bsky.social · 09/02/2025
With Helen Ziavras at the Thalassemia Foundation of Canada’s annual gala. Helen was the first Canadian patient with beta thal major to have a child of her own, which shows how much things have changed for what was once considered a pediatric diagnosis
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Jeremy Konyndyk @jeremykonyndyk.bsky.social · 06/02/2025
Mind-boggling wreckage. Among the lifesaving programs now disrupted by Elon’s attack on @USAID: phase 1 trials for a possible HIV vaccine.
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