iiinova — where your digital self keeps evolving

Jacob Jameson 📊 @jacobjameson.com · 28/06/2026

Target trial emulation is articulating the causal question in the form of the protocol of a hypothetical randomized trial that would provide the answer, then explicitly emulating the components of that protocol using the observational data jamanetwork.com/journals/jam...

jamanetwork.com

Target Trial Emulation for Causal Inference From Observational Data

This Guide to Statistics and Methods describes the use of target trial emulation to design an observational study so it preserves the advantages of a randomized clinical trial, points out the limitati...

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Jacob Jameson 📊 @jacobjameson.com · 28/06/2026

New Substack post related to some recently developed skills: Target Trial Emulation Skills for Claude Code jacobjameson.substack.com/p/target-tri...

jacobjameson.substack.com

Target Trial Emulation Skills for Claude Code

Most of the damage in observational research is done before a single model is fit.

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Center for Health Decision Science (CHDS) @ctrdecisionscience.bsky.social · 24/06/2026

Congratulations to CHDS' Jacob Jameson (@jacobjameson.com) for becoming the first repeat awardee of the Dean’s Award for Excellence in Student Teaching from the Harvard Kennedy School in more than a decade. hsph.me/jameson-HKS-...

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Center for Health Decision Science (CHDS) @ctrdecisionscience.bsky.social · 03/04/2026

CHDS doctoral student Jacob Jameson (@jacobjameson.com) was a finalist in the Three Minute Thesis (3MT®) competition for his thesis, “The Impact of Batching Advanced Imaging Tests in Emergency Departments.” hsph.me/jameson-fina...

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Jacob Jameson 📊 @jacobjameson.com · 11/01/2026

⏰ 3 days left! SMDM (@smdm.bsky.social) 2026 short course proposals due Tuesday (I'm short course co-chair this year) Past topics: DES in R, causal inference, measuring preferences, value of information, reproducible programming Oslo 🇳🇴 | 6.28–7.1 #smdm2026

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Center for Health Decision Science (CHDS) @ctrdecisionscience.bsky.social · 17/09/2025

Congratulations to CHDS's @jacobjameson.com and all the finalists!

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Jacob Jameson 📊 @jacobjameson.com · 17/09/2025

Excited to be named a finalist for the INFORMS Health Applications Society student paper competition for my paper on discretionary image batching in the emergency department! Paper here 👇 papers.ssrn.com/sol3/papers....

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Harold Pollack @haroldpollack.bsky.social · 13/08/2025

Losing a friend. Older men have the highest suicide rate of any demographic group. This challenge doesn't get nearly the attention it should. www.chicagotribune.com/2025/08/13/o...

chicagotribune.com

Harold Pollack: I studied the high male suicide rate. Then I lost my friend to it.

We middle-aged and older men face higher suicide rates than are found among our teenage sons and grandsons, or among women at any age.

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Center for Health Decision Science (CHDS) @ctrdecisionscience.bsky.social · 30/06/2025

Check out this new article by CHDS doctoral student @jacobjameson.com and colleagues

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Jacob Jameson 📊 @jacobjameson.com · 28/06/2025

Findings suggest that older males may be particularly immune to the benefits of existing regulations such as policies targeting age minimums

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Jacob Jameson 📊 @jacobjameson.com · 28/06/2025

What’s new? 📍 We combine CDC mortality data with state gun policy scores (2018–2022) 📍 We reveal where and when suicide risks diverge most by sex & policy 🔵 In permissive states, male suicide risk is: • Higher in YA (15–34) • Steepest in late life (65+) • Driven by firearms

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Jacob Jameson 📊 @jacobjameson.com · 28/06/2025

🚨 NEW in American Journal of Preventive Medicine with Nate Glasser, Nabil Baker, Harold Pollack, & Elizabeth Tung We show that permissive state firearm policies amplify sex differences in suicide—especially among young and older men 🔗 t.co/1kZ24LPkmW

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Jacob Jameson 📊 @jacobjameson.com · 28/05/2025

Unfortunately, one of the many the grants canceled at @Harvard.edu was my T32 in Comparative Effectiveness Research for Suicide Prevention If you’re coming to #SMDM47 @smdm.bsky.social come see the previously funded great work we are doing related to suicide prevention

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Jacob Jameson 📊 @jacobjameson.com · 15/05/2025

If you’re looking to improve your collaborative workflow, computational reproducibility, or just how to make the most out of version control — this is for you 👇👇

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Center for Health Decision Science (CHDS) @ctrdecisionscience.bsky.social · 14/05/2025

If you are going to @smdm.bsky.social consider this short course with @madisoncoots.com and CHDS's @jacobjameson.com

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Jacob Jameson 📊 @jacobjameson.com · 05/03/2025

Woo 🥳 3rd consecutive year I will be teaching my reproducibility and project management short course at #SMDM annual meeting ALSO if anyone knows any health/med journals looking to up their code sharing and reproducibility requirements please let me know 🙏

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Jacob Jameson 📊 @jacobjameson.com · 04/03/2025

🚨New in Clinical Pharmacology & Therapeutics We find underrepresented groups have significantly lower exposure to medications with actionable PGx guidance—highlighting a critical obstacle to equitable genomically-guided personalized medicine 💊 ascpt.onlinelibrary.wiley.com/doi/10.1002/...

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Jacob Jameson 📊 @jacobjameson.com · 19/02/2025

Reminded of a special memory: in 4th grade my best friend Zach came to school kinda down. I asked what’s wrong and he said he just listened to the saddest song and it’s got him feeling kinda down. He pulls out his iPod to have me listen to the theme song from the tv show Scrubs

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Jacob Jameson 📊 @jacobjameson.com · 05/02/2025

We find that quasi random assignment to a “batcher” relative to a “sequencer” physician has implications for: LOS 📈 Imaging volume 📈 72hr return with admission 📉

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Jacob Jameson 📊 @jacobjameson.com · 05/02/2025

We examine ED physician variation in tendency to batch order diagnostic imaging (the practice of placing multiple imaging test orders at the same time).

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Jacob Jameson 📊 @jacobjameson.com · 05/02/2025

Would you rather be seen by an ED physician who orders their tests in a batch or in sequence? 👩‍⚕️👨‍⚕️🩻 New in Feb 2025 issue of HSR by Soroush Saghafian, Nicole Hodgson, Rob Huckman, and I

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Jacob Jameson 📊 @jacobjameson.com · 29/01/2025

"HKS researchers create an analytical framework that informs the ongoing medical debate over whether to use race-unaware or race-aware risk assessments." @madisoncoots.com 👏👏👏 t.co/95lyhM9Md4

t.co

https://www.hks.harvard.edu/faculty-research/policy-topics/health/should-race-be-used-determining-risk-disease-yes-and-no/

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Jacob Jameson 📊 @jacobjameson.com · 17/01/2025

Join our lab! PIAS-Lab at Harvard Kennedy School is accepting new applications for a Postdoctoral Fellow position. More information can be found 👇👇👇 scholar.harvard.edu/sites/schola...

scholar.harvard.edu

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Madison Coots @madisoncoots.com · 09/01/2025

So excited this finally out!! 🥳 Thread on our new paper 👇

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Alex Chohlas-Wood @alexchohlaswood.com · 08/01/2025

NEW in Management Science! My coauthors and I came up with a new consequentialist approach to designing equitable algorithms. Instead of imposing fairness criteria on an algorithm (like equal false negative rates), we aim for good outcomes. More in the 🧵 below! (1/)

A screenshot of the first page of our paper, Learning to Be Fair, showing the title and abstract.

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Jacob Jameson 📊 @jacobjameson.com · 22/12/2024

Happy birthday to my beautiful fiancée @madisoncoots.com ❤️

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Madison Coots @madisoncoots.com · 13/12/2024

🚨 Excited to share our new article in @annualreviews.bsky.social. Working with Kristin Linn, @5harad.com, Amol Navathe, and Ravi Parikh, we examine the fairness debates of seven prominent and controversial healthcare algorithms.🧵 madisoncoots.com/files/racial...

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Madison Coots @madisoncoots.com · 05/12/2024

The use of race in clinical risk models is heavily debated. While race-aware models can be more accurate, some are concerned about reinforcing racialized views of medicine. In our paper, we offer a new perspective on this debate. 🧵👇https://annals.org/aim/article/doi/10.7326/M23-3166

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Jacob Jameson 📊 @jacobjameson.com · 04/12/2024

Final office hours today for MPP microeconomics at the Kennedy school. Absolutely packed!

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Sharad Goel @5harad.com · 04/12/2024

Using race in medical risk assessments is hotly debated, with some arguing that doing so improves accuracy while others worry it reinforce pernicious attitudes. With @madisoncoots.com and colleagues, we identify a statistical twist that's been largely overlooked. 5harad.com/papers/race-...

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Giuseppe Tarantino, PhD @giuseppetara.bsky.social · 29/11/2024

1/10🚨 New Findings Alert! 🚨 Discover how genomic heterogeneity and ploidy help predict intrinsic resistance to anti-PD-1 immune checkpoint blockade (ICB) in metastatic melanoma. 🧬https://www.science.org/doi/10.1126/sciadv.adp4670 📝 Key takeaways from our latest study: 🧵👇

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Vincent Arel-Bundock @vincentab.bsky.social · 02/12/2024

Our JSS article is out! And now I get to focus on {marginaleffects} 1.0.0. Stay tuned. www.jstatsoft.org/article/view...

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Kevin Griffith @assumenormality.bsky.social · 02/12/2024

Applications for the Marshfield Institute's summer 2025 research internship program are now open through February 9th marshfieldresearch.org/srip

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Jacob Jameson 📊 @jacobjameson.com · 01/12/2024

Damn I know Twitter is suffering because I’m only gaining like 1 sexbot follower for every 10 followers I lose

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Jacob Jameson 📊 @jacobjameson.com · 30/11/2024

Absolutely sick airport find 💀

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Jacob Jameson 📊 @jacobjameson.com · 30/11/2024

The decision tree model using heterogeneity & ploidy achieved: ✅ High specificity (97%) ✅ Strong PPV (90%) This helps identify patients unlikely to benefit from single-agent aPD-1 ICB, who might need combo therapies.

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Jacob Jameson 📊 @jacobjameson.com · 30/11/2024

Across different cohorts, low ploidy 📉 and high heterogeneity 📈 robustly identify patients with intrinsic resistance to aPD-1 therapy

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Jacob Jameson 📊 @jacobjameson.com · 30/11/2024

‼️Genomic heterogeneity and ploidy help predict intrinsic resistance to anti-PD-1 immune checkpoint blockade (ICB) in metastatic melanoma. 🧬‼️ www.science.org/doi/10.1126/...

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Jacob Jameson 📊 @jacobjameson.com · 30/11/2024

Seems kinda ridiculous that it’s probably primarily first gen students who have work study and they don’t even know what that means

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Jacob Jameson 📊 @jacobjameson.com · 30/11/2024

I had work study all of undergrad and didn’t know what it meant until I graduated. Worked at Ross and Goodwill all of college so I just never used it. Just had lunch with my cousin who’s a freshman at Cal— also had work study and didn’t know what it meant. Why tf don’t universities tell you??

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Jacob Jameson 📊 @jacobjameson.com · 28/11/2024

Incredibly thankful for my fiancée @madisoncoots.com who improves every aspect of my life

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Jacob Jameson 📊 @jacobjameson.com · 24/11/2024

#postdoc opportunity! Interested in ML and healthcare operations research? The Public Impact Analytics Science (PIAS) Lab at the @harvardkennedy.bsky.social has a new round of hiring for Postdoctoral Fellow positions! 👇👇 scholar.harvard.edu/sites/schola...

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Jacob Jameson 📊 @jacobjameson.com · 28/11/2024

no way people are calling Bluesky posts “skeets” (sky + tweet). I just saw someone use the term reskeet seriously. I can’t do it

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