Our new paper is officially out! www.neurology.org/doi/10.1212/...
We found that MIF contributes to peripheral immune cell infiltration to the CNS during disease. When MIF's tautomerase domain was mutated, sick mice were protected against neuronal inflammation, gliosis, and neurodegeneration.
neurology.org
MIF Tautomerase Inhibition Protects Neurons From Immune-Mediated Cell Death | Neurology Neuroimmunology & Neuroinflammation
Background and ObjectivesMultiple sclerosis (MS) is characterized by peripheral immune cell infiltration into
the central nervous system (CNS) and associated reactive gliosis, demyelination, and
neuro...
