Reposted by Isaia VardanegaNature Plants @natplants.nature.com · 09/01/2026New Article: "Imputation integrates single-cell and spatial gene expression data to resolve transcriptional networks in barley shoot meristem development" rdcu.be/eYiMF With Research Briefing rdcu.be/eYiM7 1189
Reposted by Isaia Vardanegaedgardemesa.bsky.social @edgardemesa.bsky.social · 08/01/2026It's finally out!... Using single-cell and spatial transcriptome data, and data imputation, we created BARVISTA, a website able to perform almost genome-wide information on gene expression profiles at single-cell resolution in barley spikes! www.nature.com/articles/s41...nature.comImputation integrates single-cell and spatial gene expression data to resolve transcriptional networks in barley shoot meristem development - Nature PlantsSpatially resolved gene expression during barley development was done by integrating an scRNA-seq dataset from cells with unknown position with spatial transcriptomics. This dataset is publicly availa... 24421
Reposted by Isaia VardanegaMichael Raissig @michaelraissig.bsky.social · 13/10/2025Happy to share our recent thoughts on how grasses form and pattern stomata doi.org/10.1016/j.pb... 🌾From fate establishment, through within-file patterning to dumbbell formation🌾 Congrats to @lbmountain.bsky.social on getting two publications out in a single day - a first for the lab! 03011
Reposted by Isaia VardanegaMichael Raissig @michaelraissig.bsky.social · 05/11/2025A wonderful collaboration with our colleagues from Düsseldorf within the @cerealcell.bsky.social consortium. @isaiavardanega.bsky.social @simonrdg.bsky.social Jan Maika. Thanks to the sequencing facilities at Uni Heidelberg and Uni Bern, and past and present team members for this "tour de force" 152
Reposted by Isaia Vardanega闵娅(Min Ya; Minya) PhD @minyaaa.bsky.social · 07/08/2025I’m proud to present the main work from my postdoc, 3+ years in making from scratch, my ultimate #MimulusPropaganda up till now: The Moment That Symmetry Breaks. #plantscience #development #imaging #microscopy 🧪🌸🔬 w. Captain Yaowu & @biancatash.bsky.social www.biorxiv.org/content/10.1... 1322866
Isaia Vardanega @isaiavardanega.bsky.social · 12/06/2025From Tip to Grain: Sculpting Barley Inflorescence Through the Regulation of Meristem Activity thenode.biologists.com/from-tip-to-...thenode.biologists.comFrom Tip to Grain: Sculpting Barley Inflorescence Through the Regulation of Meristem Activity - the NodeWritten by Isaia Vardanega Behind the Paper Story of “CLAVATA signalling shapes barley inflorescence by controlling activity and determinacy of shoot 176
Reposted by Isaia VardanegaRüdiger Simon @simonrdg.bsky.social · 26/05/2025Meristems shape plant architectures, and grasses generate a complex array of them. To characterise barley vegetative SAMs and spike development, we used single cell and spatial transcriptome data and integrated them in a new database, BARVISTA. A click on a cell now..... tinyurl.com/38c3mf5d 27542
Reposted by Isaia VardanegaMary Williams @PlantTeaching @plantteaching.bsky.social · 23/05/2025#PlantScience Research Weekly: May 23, 2025 plantae.org/plant-scienc... Lost in translation; How to eat an idea; RNA editing in mitochondria; Non-destructive ubiquitin tagging by COP1; When CLV walked in fields of gold (1/2) 141
Reposted by Isaia VardanegaMary Williams @PlantTeaching @plantteaching.bsky.social · 23/05/2025Featuring work by @roederlab.bsky.social @rothamsted.bsky.social @isaiavardanega.bsky.social @simonrdg.bsky.social @adhansonlab.bsky.social 021
Reposted by Isaia Vardanegaedgardemesa.bsky.social @edgardemesa.bsky.social · 11/05/2025I am thrilled to share our work on integrating single-cell and spatial transcriptomics. Here, we assign a spatial position to protoplasts by gene expression imputation, allowing us to dissect regulatory networks during meristem and organ determination in barley. www.biorxiv.org/content/10.1...biorxiv.orgImputation integrates single-cell and spatial gene expression data to resolve transcriptional networks in barley shoot meristem developmentGrass inflorescences are composite structures, featuring complex sets of meristems as stem cell niches that are initiated in a repetitive manner. Meristems differ in identity and longevity, generate b... 5148
Isaia Vardanega @isaiavardanega.bsky.social · 28/04/2025Excited to see our work finally out! 🌾🏴☠️ We show how HvCLV1 and HvFCP1 shape barley inflorescence using innovative techniques and some cool microscopy. Huge thanks to everyone involved in this study! t.co/ofButB3fRot.cohttps://www.nature.com/articles/s41467-025-59330-z 11411
Reposted by Isaia VardanegaPlant Physiology @plantphys.bsky.social · 03/04/2025PHOTOPERIOD 1 enhances stress resistance and energy metabolism to promote spike fertility in barley under high ambient temperatures (Tianyu Lan, Agatha Walla, Kumsal Ecem Çolpan Karışan, et. al.) academic.oup.com/plphys/advan... #PlantScienceacademic.oup.com 073
