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Reposted by Federico Napoli

paulschanda.bsky.social @paulschanda.bsky.social · 14/01/2026

📢 New preprint alert! How do proteins enter mitochondria? We uncovered a surprising mechanism at the mitochondrial entry gate—using #NMR, in vivo single-particle tracking, yeast experiments, and MD simulations to crack the code. www.biorxiv.org/content/10.6... #StructuralBiology #Mitochondria 🧵 1/8

biorxiv.org

A dynamic displacement mechanism drives protein import into mitochondria

Most mitochondrial proteins are produced in the cytosol and imported through the translocase of the outer mitochondrial membrane (TOM) to reach their final destination. Although this protein entry gat...

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Reposted by Federico Napoli

Magnetic Resonance News @nmr900.bsky.social · 18/12/2025

Scientific Data (open) NMRexp, an open, curated collection of 3.3 million experimental NMR records for six nuclei (1H, 13C, 19F, 31P, 29Si, 11B), extracted from nearly 200 thousand Supporting Information documents published between 2010 and 2024 www.nature.com/articles/s41... #NMRchat #NMR 🧲

nature.com

NMRexp: A database of 3.3 million experimental NMR spectra - Scientific Data

Scientific Data - NMRexp: A database of 3.3 million experimental NMR spectra

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Reposted by Federico Napoli

Ben Williamson @benpatrickwill.bsky.social · 19/12/2025

Closing out my year with a journal editor shocker 🧵 Checking new manuscripts today I reviewed a paper attributing 2 papers to me I did not write. A daft thing for an author to do of course. But intrigued I web searched up one of the titles and that's when it got real weird...

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Federico Napoli @iomichiamofede.bsky.social · 17/11/2025

So excited to announce the first 🧲 Next Austrian NMR Meeting 🧲, happening @ ISTA, Feb 26–27, 2026! Plus a satellite workshop, 💊 “ #NMR in #DrugDiscovery” 🧭 on Feb 25! 📅 Registration: Dec 1, 2025 🌐 Program, venue: austrian-nmr-meeting.pages.ist.ac.at #NMRchat #Austria 1/4

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Federico Napoli @iomichiamofede.bsky.social · 07/11/2025

So cool to work with three great scientists and friends in the Vienna #NMR scene! Sonja Knödlstorfer⚛️, @giorgia-toscano.bsky.social🧪 and @aptaszek.bsky.social💻. New pulse sequence, precursor, and computational approach: assigning methyls was never this easy! www.sciencedirect.com/science/arti...

sciencedirect.com

A Novel HMBC-CC-HMQC NMR Strategy for Methyl Assignment Using Triple-13C-Labeled α-Ketoisovalerate Integrated with UCBShift 2.0

In this study, we describe an integrated approach for methyl group assignment comprising precursor-based selective methyl group labeling, a novel puls…

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Reposted by Federico Napoli

Instruct-ERIC @instruct-eric.bsky.social · 31/10/2025

We were delighted to hear from Daniele Trivellato at the 52nd National Conference on Magnetic Resonance, outlining their research on intrinsically disordered proteins! Daniele accessed Instruct through the R&D funding programme - find out more here instruct-eric.org/rd-project-a...

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Federico Napoli @iomichiamofede.bsky.social · 02/09/2025

Team effort with @darjarohden.bsky.social 💪🏼👩‍🔬 targeting my second favourite amino acid by solid-state NMR. Many motion timescales accessible. And the next amino acid is already in the crosshairs (my third favourite 😏). share.google/Q1ZzwJwDjjwA... (yeah nothing beats tryptophan)

share.google

Arginine dynamics probed by magic-angle spinning NMR with a specific isotope-labeling scheme

The specific introduction of 1H-13C or 1H-15N moieties into otherwise deuterated proteins holds great potential for high-resolution solution and magic…

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