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INHALE

@inhale-trial.bsky.social
17 followers 11 following 12 posts

NIHR-funded research programme evaluating the use of rapid molecular diagnostics for HAP/VAP in Critical Care. norwichctu.uea.ac.uk/inhale norwichctu.uea.ac.uk/inhale-pdg

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Reposted by INHALE
UK CTU Network @ukctunetwork.org · 24/11/2025
🌍 World AMR Awareness Week 2025 | Preventing antimicrobial resistance together Antimicrobial resistance (AMR) remains one of the biggest threats to global health - demanding innovation, collaboration, & better understanding of how we use antibiotics in clinical care. Read more tinyurl.com/yw792han
tinyurl.com
INHALE: Potential of Molecular Diagnostics for Hospital-Acquired and Ventilator-Associated Pneumonia in UK Critical Care | UKCRC Registered CTU Network
🌍 World AMR Awareness Week 2025 | Preventing antimicrobial resistance together Antimicrobial resistance (AMR) remains one of the biggest threats to global health — demanding innovation, collaboration...
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INHALE @inhale-trial.bsky.social · 12/08/2025
INHALE WP3 RCT health economic analysis now published in Critical Care. The Pneumonia Panel PCR had lower average ICU costs and was cost effective for antimicrobial stewardship, but not clinical cure. Read in full at: rdcu.be/eAmSD
rdcu.be
Cost-effectiveness of rapid, ICU-based, syndromic PCR in hospital-acquired pneumonia: analysis of the INHALE WP3 multi-centre RCT | Critical Care
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INHALE @inhale-trial.bsky.social · 10/06/2025
‘INHALE Poem II – A slight diversion’ shares the journey of the INHALE study, describing its hopes, challenges and the implications of the research. This poem was written and performed by Amander Wellings, of the INHALE Patient, Carer and Public Involvement (PPI) group. youtu.be/-UUBzbSmEo0?...
youtu.be
INHALE Poem II - A Slight Diversion
YouTube video by INHALE Trial
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INHALE @inhale-trial.bsky.social · 25/04/2025
What is the impact of seeking pathogens by rapid molecular diagnostic methods on antibiotic stewardship and the clinical outcomes in hospital-acquired and ventilator-associated pneumonia (HAP and VAP)? Visual abstract below and full paper available online at rdcu.be/ehlAu
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Reposted by INHALE
Ilan Schwartz @germhuntermd.bsky.social · 05/03/2025
Our call to to resistance, led by @angelahuttner.bsky.social and first published in @cmicomms.bsky.social, now published in @cmijournal.bsky.social too www.clinicalmicrobiologyandinfection.com/article/S119...
clinicalmicrobiologyandinfection.com
From medical editors: a call to the global infectious diseases and clinical microbiology community
The views expressed by the authors are their own and do not necessarily reflect those of the European Society for Clinical Microbiology and Infectious Diseases (ESCMID) or Elsevier.
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INHALE @inhale-trial.bsky.social · 26/02/2025
INHALE compared rapid testing with standard care used to diagnose pneumonia in intensive care. Rapid testing gave faster results than standard care and improvements in antibiotic use. But, the machine did not improve cure of pneumonia, so more research is needed to understand why.
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INHALE @inhale-trial.bsky.social · 20/02/2025
1/4 Rapid molecular diagnostic tests for pathogens and resistance genes may improve antibiotic prescribing decisions and stewardship. However, clinicians’ desire to protect their patient with an antibiotic often overrides more distal concerns about possible resistance selection,
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Reposted by INHALE
UCL Centre for Behavioural Medicine @ucl-cbm.bsky.social · 07/02/2025
🚨 New Paper from Dr SJ Stewart and the INHALE team @inhale-trial.bsky.social “Guidelines vs Mindlines” published in Antimicrobial Agents and Chemotherapy journals.asm.org/doi/10.1128/...
journals.asm.org
Guidelines vs mindlines: a qualitative investigation of how clinicians’ beliefs influence the application of rapid molecular diagnostics in intensive care | Antimicrobial Agents and Chemotherapy
Rapid molecular diagnostic tests for pathogens and resistance genes may improve antibiotic-prescribing decisions and stewardship. However, clinicians’ desire to protect their patients with antibiotics...
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INHALE @inhale-trial.bsky.social · 18/02/2025
1/2 The INHALE WP3 randomised trial provides multi-centre evidence that rapid syndromic PCR, delivered at the point-of care in the ICU improved antibiotic stewardship by 21% in absolute terms. Equivalence of clinical cure was not demonstrated link.springer.com/article/10.1...
link.springer.com
INHALE WP3, a multicentre, open-label, pragmatic randomised controlled trial assessing the impact of rapid, ICU-based, syndromic PCR, versus standard-of-care on antibiotic stewardship and clinical out...
Purpose INHALE investigated the impact of seeking pathogens by PCR on antibiotic stewardship and clinical outcomes in hospital-acquired and ventilator-associated pneumonia (HAP and VAP). Methods This ...
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