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ijaa-isac.bsky.social

@ijaa-isac.bsky.social

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ijaa-isac.bsky.social @ijaa-isac.bsky.social · 30/09/2026

🧠🦠 Let's make AI our friend! From predicting antimicrobial resistance and infections to supporting antibiotic stewardship and accelerating AI-driven drug discovery 📚 Explore recent advances: www.sciencedirect.com/special-issu... #AI #AMR @isacworld.bsky.social

sciencedirect.com

ijaa-isac.bsky.social @ijaa-isac.bsky.social · 23/09/2026

🙌 A big thank you to our amazing reviewers! As we reflect on Peer Review Week last week, we want to recognise the time and expertise you contribute to strengthening scientific research. 🔬 #PeerReviewWeek #Research @isacworld.bsky.social

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ijaa-isac.bsky.social @ijaa-isac.bsky.social · 16/09/2026

🔥Check out the Hot Topic: www.sciencedirect.com/science/arti... Growing interest in phage therapy but important knowledge gaps and barriers remain...🦠 #PhageTherapy #AMR @isacworld.bsky.social

sciencedirect.com

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ijaa-isac.bsky.social @ijaa-isac.bsky.social · 23/08/2026

⭐ Editor's Choice 🚨 The growing accumulation of antibiotic resistance is a serious concern! New research finds ST1545 Klebsiella pneumoniae carrying genes that make them resistant to important antibiotics - carbapenems and tigecycline www.sciencedirect.com/science/arti... @isacworld.bsky.social

sciencedirect.com

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ijaa-isac.bsky.social @ijaa-isac.bsky.social · 15/08/2026

📔New issue is out! Featuring the latest research on phage therapy, novel antimicrobials, diagnostics & resistance mechanisms! Explore more: www.sciencedirect.com/journal/inte... @isacworld.bsky.social

sciencedirect.com

International Journal of Antimicrobial Agents | Vol 67, Issue 9, September 2026 | ScienceDirect.com by Elsevier

Read the latest articles of International Journal of Antimicrobial Agents at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature

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ijaa-isac.bsky.social @ijaa-isac.bsky.social · 05/08/2026

🌟A fitting tribute to Professor Alasdair Macintosh Geddes—a pioneering infectious diseases physician and outstanding mentor www.sciencedirect.com/science/arti... @isacworld.bsky.social

sciencedirect.com

Professor Alasdair Macintosh Geddes: A life of science, service, and kindness

All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.

ijaa-isac.bsky.social @ijaa-isac.bsky.social · 22/07/2026

🔥 Hot Topic New antibiotics offer hope but are they reaching the patients who need them? Access to newly approved antibacterials across Asian countries remains limited, with substantial approval delays www.sciencedirect.com/science/arti... #Antibiotics #InfectiousDiseases @isacworld.bsky.social

sciencedirect.com

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ijaa-isac.bsky.social @ijaa-isac.bsky.social · 15/07/2026

📢 New Issue | IJAA Volume 67, Issue 8 The latest issue is now online! Featuring: 🔹 Reviews on antifungal prophylaxis and fluoroquinolone prophylaxis 🔹 Insights into novel therapeutics and machine learning Explore more: www.sciencedirect.com/journal/inte... @isacworld.bsky.social

sciencedirect.com

International Journal of Antimicrobial Agents | Vol 67, Issue 8, August 2026 | ScienceDirect.com by Elsevier

Read the latest articles of International Journal of Antimicrobial Agents at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature

ijaa-isac.bsky.social @ijaa-isac.bsky.social · 08/07/2026

🥳We're proud to share that the International Journal of Antimicrobial Agents has achieved a 2025 Impact Factor of 5.0, up from 4.6 in 2024. A sincere thank you to our authors, reviewers, editors and readers! @isacworld.bsky.social

ijaa-isac.bsky.social @ijaa-isac.bsky.social · 30/06/2026

New study: Stepwise cefiderocol exposure in NDM-producing Klebsiella pneumoniae selected recurrent baeS variants and reshaped iron uptake, porin expression, blaNDM-5, and biofilm responses. www.sciencedirect.com/science/arti... @isacworld.bsky.social

sciencedirect.com

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ijaa-isac.bsky.social @ijaa-isac.bsky.social · 23/06/2026

New IJAA study tracks in vivo tigecycline resistance in ST540 CRAB, revealing adeS N125S-driven AdeABC upregulation, collateral sensitivity to cefoperazone/sulbactam, and ICU transmission. www.sciencedirect.com/science/arti... @isacworld.bsky.social

sciencedirect.com

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ijaa-isac.bsky.social @ijaa-isac.bsky.social · 16/06/2026

MALDI-TOF MS combined with machine learning accurately predicts ceftriaxone resistance in Salmonella (ROC-AUC up to 0.924). This interpretable, web-based approach could accelerate targeted therapy and strengthen antimicrobial stewardship. www.sciencedirect.com/science/arti... @isacworld.bsky.social

sciencedirect.com

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ijaa-isac.bsky.social @ijaa-isac.bsky.social · 11/06/2026

New in IJAA (Vol.67, Issue 7): AI-guided AMR prediction, emerging CZA–cefiderocol cross-resistance, phage therapy advances, polymyxin B PK, and cefiderocol clinical evidence. www.sciencedirect.com/journal/inte... @isacworld.bsky.social

sciencedirect.com

International Journal of Antimicrobial Agents | Vol 67, Issue 7, July 2026 | ScienceDirect.com by Elsevier

Read the latest articles of International Journal of Antimicrobial Agents at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature

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ijaa-isac.bsky.social @ijaa-isac.bsky.social · 03/06/2026

Using 5,239 Klebsiella pneumoniae genomes, a machine learning model accurately predicted multi-level antimicrobial resistance for 11 antibiotics (mean AUC >0.9), advancing precision therapy and AMR control. www.sciencedirect.com/science/arti... @isacworld.bsky.social

sciencedirect.com

Machine learning-based prediction of multi-level anti-microbial resistance in Klebsiella pneumoniae using whole-genome sequencing data

In this study, we developed an integrated approach for accurate and comprehensive prediction of anti-microbial resistance (AMR) using whole-genome seq…

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ijaa-isac.bsky.social @ijaa-isac.bsky.social · 26/05/2026

IJAA Volume 67 Issue 6 features the latest advances in AMR, AI-guided infection prediction, CRKP resistance, phage therapy, anti-biofilm strategies, and antimicrobial PK/PD optimization. www.sciencedirect.com/journal/inte... @isacworld.bsky.social

sciencedirect.com

International Journal of Antimicrobial Agents | Vol 67, Issue 6, June 2026 | ScienceDirect.com by Elsevier

Read the latest articles of International Journal of Antimicrobial Agents at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature

ijaa-isac.bsky.social @ijaa-isac.bsky.social · 19/05/2026

Repurposing sulfamethoxazole through gold nanocluster modification: SMZ_Au NCs showed potent antibacterial and anti-biofilm activity against MDR Gram-negative bacteria, with promising in vivo efficacy and safety. www.sciencedirect.com/science/arti... @isacworld.bsky.social

sciencedirect.com

Repurposing sulfamethoxazole via gold nanocluster modification for antibacterial and anti-biofilm activity against multidrug-resistant Gram-negative bacteria

The global spread of antimicrobial resistance represents a severe threat to public health, with infections caused by multidrug-resistant Gram-negative…

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ijaa-isac.bsky.social @ijaa-isac.bsky.social · 11/05/2026

AI + MALDI-TOF MS rapidly predicted antimicrobial resistance in Acinetobacter baumannii infection with >83% accuracy, supporting faster AI-assisted AST in clinical practice. www.sciencedirect.com/science/arti... @isacworld.bsky.social

sciencedirect.com

Development and validation of a predictive model for profiling antibiotic resistance phenotypes of Acinetobacter baumannii strains via clinical MALDI-TOF mass spectra: A multicenter study

Acinetobacter baumannii is a significant pathogen responsible for healthcare-acquired infections (HAIs), posing challenges due to its rising resistanc…

ijaa-isac.bsky.social @ijaa-isac.bsky.social · 07/05/2026

IJAA Volume 67, Issue 5 is now online, featuring advances in phage therapy, AMR prediction, resistance mechanisms, PK/PD, and antimicrobial stewardship. Explore the latest updates in infectious diseases research. www.sciencedirect.com/journal/inte... @isacworld.bsky.social

sciencedirect.com

International Journal of Antimicrobial Agents | Vol 67, Issue 5, May 2026 | ScienceDirect.com by Elsevier

Read the latest articles of International Journal of Antimicrobial Agents at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature

ijaa-isac.bsky.social @ijaa-isac.bsky.social · 02/05/2026

SMART ML model predicts postoperative infection risk (AUC 0.86), enabling targeted prevention and antimicrobial stewardship. www.sciencedirect.com/science/arti... @isacworld.bsky.social

sciencedirect.com

Surgical MAchine learning model for predicting Risk of postoperative infecTions in general elective surgery (SMART): A modelling study

To apply a machine learning (ML) model that we developed and internally validated for predicting postoperative infection likelihood after elective gen…

ijaa-isac.bsky.social @ijaa-isac.bsky.social · 21/04/2026

China hospital antibiotic use fell (46.8→35.3 DDDs/100 PDs, 2013–2024), but shifts to Watch/Reserve raise AMR risks. By 2030, use may drop 11.4%, highlighting need for targeted stewardship. www.sciencedirect.com/science/arti... @isacworld.bsky.social

sciencedirect.com

Present trajectories to forecasted future: A longitudinal analysis of hospital antibiotic use in China from 2013 to 2024 and projections to 2030

To characterize the decadal trends in antibiotic use among hospitalized patients in China, and to project consumption trajectories through 2030.We ana…

ijaa-isac.bsky.social @ijaa-isac.bsky.social · 15/04/2026

Phage–colistin synergy depends on order: phage-first enhances killing, colistin-first weakens phage. Only simultaneous use suppresses resistance in MDR A. baumannii. www.sciencedirect.com/science/arti... @isacworld.bsky.social

sciencedirect.com

Treatment sequences of a phage and colistin combination trigger different evolution pathways of a multidrug-resistant Acinetobacter baumannii yielding distinct treatment outcomes

To better understand the underlying mechanisms of treatment order of phage and antibiotic synergy (PAS), particularly in the context of planktonic bac…

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ijaa-isac.bsky.social @ijaa-isac.bsky.social · 07/04/2026

Cefiderocol resistance emerging in China: blaNDM-carrying E. coli shows high resistance via CirA/PBP3 mutations, with clonal spread risk. Urgent need for One Health surveillance. www.sciencedirect.com/science/arti... @isacworld.bsky.social

sciencedirect.com

Molecular mechanisms and clonal distribution of cefiderocol-resistant blaNDM-carrying Escherichia coli: A multi-centre study in China

Reports on cefiderocol resistance are increasing globally despite its unavailability in China. The blaNDM-carrying Escherichia coli was one of the mos…

ijaa-isac.bsky.social @ijaa-isac.bsky.social · 30/03/2026

Imagine viruses that fight bacteria instead of causing disease—phages are doing just that! From hospitals to farms to crops, One Health approach is turning phage therapy into a real-world weapon against AMR. www.sciencedirect.com/science/arti... #PhageTherapy #OneHealth @isacworld.bsky.social

sciencedirect.com

Phage therapy in China: Arming the One Health approach

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ijaa-isac.bsky.social @ijaa-isac.bsky.social · 24/03/2026

Can phages, probiotic strains & host‑directed therapies reshape our fight against AMR? 🦠 👀 Check them out in the latest research: www.sciencedirect.com/journal/inte... #AMR #InfectiousDiseases #PhageTherapy #Antimicrobials #HostDirectedTherapy @isacworld.bsky.social

sciencedirect.com

International Journal of Antimicrobial Agents | Vol 67, Issue 3, March 2026 | ScienceDirect.com by Elsevier

Read the latest articles of International Journal of Antimicrobial Agents at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature

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ijaa-isac.bsky.social @ijaa-isac.bsky.social · 18/03/2026

🚨 Hot Topic Artificial intelligence and machine learning are transforming antimicrobial research—accelerating drug discovery, improving resistance prediction and enabling precision therapy to outpace superbugs. www.sciencedirect.com/science/arti... #AMR #AI #machinelearning @isacworld.bsky.social

sciencedirect.com

Artificial intelligence and machine learning in antimicrobial discovery, resistance prediction, and precision therapy

The global crisis of antimicrobial resistance (AMR) demands a paradigm shift in traditional drug discovery, and artificial intelligence (AI) is unique…

ijaa-isac.bsky.social @ijaa-isac.bsky.social · 11/03/2026

📣 Join the Editorial Team! The International Journal of Antimicrobial Agents is looking for Associate Editors, Statistical Advisors, and Editors-in-Training to help shape the future of antimicrobial research and publishing. Learn more: www.sciencedirect.com/journal/inte... @isacworld.bsky.social

sciencedirect.com

Announcements - International Journal of Antimicrobial Agents | ScienceDirect.com by Elsevier

Read the latest articles of International Journal of Antimicrobial Agents at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature

ijaa-isac.bsky.social @ijaa-isac.bsky.social · 08/02/2026

One month into 2026 — and the science is already accelerating... From model-informed precision dosing and AI-driven safety prediction to phage therapy, resistance genomics, and novel antimicrobials Check them out👉 www.sciencedirect.com/journal/inte... @isacworld.bsky.social

sciencedirect.com

International Journal of Antimicrobial Agents | Vol 67, Issue 1, January 2026 | ScienceDirect.com by Elsevier

Read the latest articles of International Journal of Antimicrobial Agents at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature

ijaa-isac.bsky.social @ijaa-isac.bsky.social · 27/01/2026

Take a look at our ISAC News and Information Page! www.sciencedirect.com/science/arti... Member perks-reduced IJAA subscription, conferences/workshops registration, project/travel grants Working groups-Join us and/or propose new groups Watch on-demand webinars and short videos @isacworld.bsky.social

sciencedirect.com

International Society of Antimicrobial Chemotherapy (ISAC) News and Information Page

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ijaa-isac.bsky.social @ijaa-isac.bsky.social · 14/01/2026

It is happening in the next few hours. See you soon~

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ijaa-isac.bsky.social @ijaa-isac.bsky.social · 10/01/2026

Join us for a special ISAC session marking One Health Awareness Month! 🌍 Launching “One Health” Special Issue and exploring how human, animal & environmental health are all connected in the fight against AMR. Register now us02web.zoom.us/webinar/regi... @isacworld.bsky.social #OneHealth #AMR

ijaa-isac.bsky.social @ijaa-isac.bsky.social · 30/12/2025

💊 tet(X4) Resistance in Klebsiella| IJAA Vol.67 Issue 1 (In progress) Global One Health dissemination of tet(X4) via mobile plasmids, often co-existing with carbapenem and colistin resistance, signals a serious public health risk. 📖 www.sciencedirect.com/science/arti... @isacworld.bsky.social

sciencedirect.com

Genome-wide insight into the evolution and global transmission of tigecycline resistant tet(X4)-carrying Klebsiella species across reservoirs

The emergence of plasmid mediated tet(X4) gene compromises the clinical utility of tigecycline and underscores growing concerns regarding its environm…

ijaa-isac.bsky.social @ijaa-isac.bsky.social · 23/12/2025

💊 Phage Depolymerases vs hvKP | IJAA Vol.67 Issue 1 (In progress) TFP41 and TSP42 strip the K2 capsule of hypervirulent K. pneumoniae, enhance immune clearance, and deliver up to 100% survival in murine pneumonia models. 📖 www.sciencedirect.com/science/arti... @isacworld.bsky.social

sciencedirect.com

Two Tail Protein-Derived Capsule Depolymerases From Phage vB_KpnS_GH-K1 are Effective Against Pneumonia Caused by K2 Serotype Klebsiella pneumoniae

Hypervirulent Klebsiella pneumoniae (hvKP) poses an escalating threat to public health and animal husbandry, underscoring the urgent need for novel an…

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ijaa-isac.bsky.social @ijaa-isac.bsky.social · 16/12/2025

💊 Predicting AKI in Glycopeptide Therapy | IJAA Vol.67 Issue 1 (In progress) An explainable XGBoost model predicts vancomycin- and teicoplanin-associated AKI, enabling early, personalized risk assessment. 📖 doi.org/10.1016/j.ij... @isacworld.bsky.social

ijaa-isac.bsky.social @ijaa-isac.bsky.social · 09/12/2025

💊 Prophage Activation & Antibiotics | IJAA Vol.67 Issue 1 (In progress) A brief review of how antibiotics drive or inhibit prophage induction, influence toxin release and gene transfer, and guide safer therapy decisions. 📖 www.sciencedirect.com/science/arti... @isacworld.bsky.social

sciencedirect.com

Antibiotic-mediated prophage activation: Mechanisms, consequences, and therapeutic implications

Prophages, as an integral part of bacterial genomes, play a pivotal role in regulating host virulence and shaping bacterial evolution. Exposure to ant…

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ijaa-isac.bsky.social @ijaa-isac.bsky.social · 02/12/2025

🌍 Nanomedicine for Phage Therapy | IJAA Vol.67 Issue 1 (In progress) A concise review of how nanoparticles, liposomes, hydrogels and nanofibers enhance phage stability, delivery and efficacy against MDR pathogens. 📖 www.sciencedirect.com/science/arti... @isacworld.bsky.social

sciencedirect.com

Nanomedicine for phage therapy: Encapsulation strategies for enhanced antimicrobial efficacy

Antibiotic resistance is a growing global health crisis, driving the need for alternative antimicrobial strategies. Phage therapy has re-emerged as a …

ijaa-isac.bsky.social @ijaa-isac.bsky.social · 25/11/2025

🚀 IJAA Vol. 66 Issue 6 is out! Highlights: global AMR burden, MRSA, One Health, AI strategies, and the Global Landscape of Phage Therapy. 📖 www.sciencedirect.com/journal/inte... @isacworld.bsky.social

sciencedirect.com

International Journal of Antimicrobial Agents | Vol 66, Issue 6, December 2025 | ScienceDirect.com by Elsevier

Read the latest articles of International Journal of Antimicrobial Agents at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature

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ijaa-isac.bsky.social @ijaa-isac.bsky.social · 18/11/2025

🌍 Commercial Phage Therapy Prospects| IJAA Vol.66 Issue 6 (In progress) Analysis reveals a surge in phage therapy patents & clinical trials, yet post-approval regulatory & economic hurdles remain for commercial success. 📖 www.sciencedirect.com/science/arti... @isacworld.bsky.social

sciencedirect.com

The prospect of approved and commercially available phage therapeutics

As antibiotic resistance of bacterial pathogens spreads, interest in bacteriophage (phage) therapy has soared again in many countries. Currently, ther…

ijaa-isac.bsky.social @ijaa-isac.bsky.social · 11/11/2025

🌍 Global Landscape of Phage Therapy | IJAA Vol.66 Issue 6 An international survey uncovers clinicians’ perspectives on phage therapy, revealing growing optimism, diverse experiences, and global challenges in clinical adoption. 📖 www.sciencedirect.com/science/arti... @isacworld.bsky.social

sciencedirect.com

Phage therapy: An international survey of attitudes and experiences amongst clinicians

Phage therapy is a promising tool to combat the global threat of antimicrobial resistance. Clinicians, as part of interdisciplinary teams, play an int…

ijaa-isac.bsky.social @ijaa-isac.bsky.social · 04/11/2025

🤖 AI Strategies to Combat AMR | IJAA Vol.66 Issue 5 Whole genome-based machine learning predicts AMR in nontyphoidal Salmonella, providing genomic insights to enhance AI-driven surveillance and precision control. 📖 www.sciencedirect.com/science/arti... @isacworld.bsky.social

sciencedirect.com

Genomic insights into nontyphoidal Salmonella: Prediction of antimicrobial resistance with whole genome-based machine learning

Nontyphoidal Salmonella is a world-leading foodborne pathogen associated with an increased rate of antimicrobial resistance (AMR) and remains endemic …

ijaa-isac.bsky.social @ijaa-isac.bsky.social · 08/10/2025

🌏 Hot Topic | IJAA Vol.66 Issue 5 Survey finds 97% of Australian ID physicians would use phage therapy if safety standards are met, highlighting its promise against drug-resistant infections and priorities for clinical use. 📖 www.sciencedirect.com/science/arti... @isacworld.bsky.social

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ijaa-isac.bsky.social @ijaa-isac.bsky.social · 03/10/2025

🌍 IJAA Vol.66, Issue 5 Hot Topic: Phage therapy in Australia. AMR highlights: WGS-based AMR prediction, polymyxin B synergy vs P. aeruginosa, CREC in China, Raman AI for MRSA/CRKP, CRKP in Portugal. 📖 www.sciencedirect.com/journal/inte... #IJAA #AMR @isacworld.bsky.social

sciencedirect.com

International Journal of Antimicrobial Agents | Vol 66, Issue 5, November 2025 | ScienceDirect.com by Elsevier

Read the latest articles of International Journal of Antimicrobial Agents at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature

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ijaa-isac.bsky.social @ijaa-isac.bsky.social · 05/09/2025

Explore the latest from IJAA (Vol. 66, Issue 4)! 🦠 Phage therapy: models & clinical use 🧬 Klebsiella resistance evolution 💊 Cefiderocol & β-lactamase detection 🔬 Serum lipids modulating S. aureus phage sensitivity 📈 Vancomycin dosing in the critically ill @isacworld.bsky.social

sciencedirect.com

International Journal of Antimicrobial Agents | Vol 66, Issue 4, October 2025 | ScienceDirect.com by Elsevier

Read the latest articles of International Journal of Antimicrobial Agents at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature

ijaa-isac.bsky.social @ijaa-isac.bsky.social · 15/07/2025

📢 New in IJAA Vol. 66, Issue 1! 🧬 AMR in the rumenofaecobiome 💊 Posaconazole in rare IFIs 🦠 IFN-λ in respiratory models 💉 Tigecycline modulates sepsis immunity 🌍 Global CRE resistance patterns 🧪 CRISPR assay for GES β-lactamase 📖 Read: www.sciencedirect.com/journal/inte...

sciencedirect.com

International Journal of Antimicrobial Agents | Vol 66, Issue 1, July 2025 | ScienceDirect.com by Elsevier

Read the latest articles of International Journal of Antimicrobial Agents at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature

ijaa-isac.bsky.social @ijaa-isac.bsky.social · 23/04/2025

Check out the latest issue! Dive into groundbreaking research on host-directed therapies, antimicrobial mechanism, multiomics informed mathematical model and the spread of antimicrobial-resistant pathogens Read now: www.sciencedirect.com/journal/inte... @isacworld.bsky.social

sciencedirect.com

International Journal of Antimicrobial Agents | Vol 65, Issue 6, June 2025 | ScienceDirect.com by ElsevierScienceDirect

Read the latest articles of International Journal of Antimicrobial Agents at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature