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Reposted by Iakovos Lazaridis

Andreas Kardamakis @kardamakis.bsky.social · 22/10/2025

(first post in this platform) happy to share our new paper on visual-based center-surround interactions in the superior colliculus, showcasing a general approach to dissect local circuit computations. @NeuroAlc

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Reposted by Iakovos Lazaridis

PLOS Biology @plosbiology.org · 17/10/2025

#Visual #salience generation involves center-surround dynamics, but what performs these computations? This study shows that the #SuperiorColliculus encodes center-surround dynamics under isolated conditions, and provides insights into the circuit implementation @plosbiology.org 🧪 plos.io/4n7RpsA

A horizontally oriented inhibitory neuron (yellow) spans the mediolateral axis of the superficial superior colliculus, with dense axonal arborization suggestive of a role in collicular surround suppression. Retinal ganglion cell terminals expressing ChR2 are shown in cyan (following intraocular AAV injection), while magenta highlights VGAT+ neurons labeled via a reporter AAV-tdTomato in a VGAT-Cre mouse. Image credit Dr. Peng Cui

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Reposted by Iakovos Lazaridis

SWEBAGS @swebags.bsky.social · 18/03/2025

Save the date and join us for a webinar about cholinergic interneurons, hosted by the Swedish Basal Ganglia Society. We are excited to have two distinguished speakers: Stephanie Cragg and Mark Howe. Everyone is welcome and no registration is required! swebags.ebrains.se/events/choli...

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Reposted by Iakovos Lazaridis

The Transmitter @thetransmitter.bsky.social · 24/01/2025

The ‘go’ and ‘no-go’ pathways in the basal ganglia are not the only pathways that control movement, as a new study reveals two additional circuits that modulate dopamine and movement. By @claudia-lopez.bsky.social #neuroskyence www.thetransmitter.org/basal-gangli...

thetransmitter.org

Newly characterized striatal circuits add twist to ‘go/no-go’ model of movement control

The two novel pathways control dopamine release in opposing ways and may link motivation and mood to action, a new study shows.

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Reposted by Iakovos Lazaridis

Dinos Meletis @meletis.bsky.social · 22/12/2024

first thing to share here! excited to share lab’s first study in Parkinson’s disease revealing the prodromal vulnerability and function of the dopamine neuron subtype defined by Anxa1 expression - a specialized system controlling procedural motor learning www.biorxiv.org/content/10.1...

biorxiv.org

Anxa1+ dopamine neuron vulnerability defines prodromal Parkinson's disease bradykinesia and procedural motor learning impairment

Progressive degeneration of dopamine neurons (DANs) defines Parkinson's disease (PD). However, the identity and function of the most vulnerable DAN populations in prodromal PD remain undefined. Here, ...

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Iakovos Lazaridis @iaklaz.bsky.social · 08/12/2024

Interested in dopamine regulation? Don’t forget the astrocytes! We’re excited to share our new preprint on astrocyte-dopamine interactions in the dorsal striatum and behavioral state transitions. @biorxiv_neursci, @mcgovernmit, @AnnMGraybiel biorxiv.org/content/10.110…

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Reposted by Iakovos Lazaridis

Elanur Yilmaz @elanuryilmaz.bsky.social · 04/12/2024

Can there be a “little brain” in the heart? This is one of the “out of the box” project that we performed as KizilLab and AmpatzisLab. Huge thanks to Andrea, Kostas and Caghan 🤘🏻 #zebrafish #heart #neuron Check this little brain of the heart: www.nature.com/articles/s41...

nature.com

Decoding the molecular, cellular, and functional heterogeneity of zebrafish intracardiac nervous system - Nature Communications

Although the heart has its own nervous system, its organization and functionality remain largely unknown. Here, the authors reveal the molecular, chemical, and functional diversity of neurons within t...

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