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Huan Li

@huanli00.bsky.social
24 followers 5 following 1 posts

Membrane proteins 🐳, cryo-EM🔬, and electrophys 🐶. Still on the way 🏃

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Reposted by Huan Li
Oli Clarke @olibclarke.bsky.social · 12/06/2025
1/x New story - the structure of the Vault cap, at 2.3Å! Matching a beautiful preprint from @sjorsscheres.bsky.social, we show that the cap of the vault particle has C13 symmetry, in contrast to the 39-fold symmetry of the body. Study lead by talented postdoc @huanli00.bsky.social from my group! ⬇️
At left, a reconstruction of the vault cap with C39 symmetry imposed; at right, the reconstruction after identifying the correct symmetry, with the three non-equivalent protomers highlighted.
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