UK Biobank is imposing new safety measures after a security incident, but safeguarding biomedical data while enabling researcher access remains a challenge.

British Journal of Cancer - Anthropometric traits, metabolic biomarkers, and pancreatic cancer risk: a causal mediation analysis in UK Biobank

Reliance on artificial-intelligence tools degrades the abilities of physicians and software engineers, studies show.

Publishes monographs dealing with cancer and closely related research fields, or related groups of papers on specific subjects of importance to cancer research.

How a research proposal generated by artificial intelligence transformed my approach to teaching and supervision.

Abstract. The relationship between diet and cancer is complex and has been the subject of scientific controversy. Recent estimates of the fraction of cance

E-mails and instant messaging are core to research — but also a distraction. Researchers should study their impact on science, and how they can claw back time to concentrate.

Stein et al. identify circulating blood proteins linked to regular moderate-to-vigorous physical activity in over 33,000 UK Biobank participants. Many of these proteins are associated with lower risk ...

With so little money to go round, the costs of competing for grants can exceed what the grants are worth. When that happens, nobody wins.

Around the world, governments are demanding that research funding follow broader political priorities. They should be careful what they wish for.

Researchers can deploy the cheap and transparent model on their own computer system.

If we don’t slow down, the research enterprise is going to crash, argues Adrian Barnett.

Second thoughts.

Artificial-intelligence systems are feeding on Wikipedia without giving back, and academic indifference is threatening the survival of what is arguably the most widely used reference work on the plane...

Background Multimorbidity is socially patterned, with lower socioeconomic position (SEP) linked to higher risk. We examined whether a Healthy Lifestyle Index (HLI) mediates the SEP–multimorbidity asso...

Information about the roles of each author of a paper can help to build trust, integrity and responsible research assessment. Coordinated efforts are needed to consolidate progress.

This research evaluates the association between a new definition of obesity with mortality data in the UK Biobank.

Causal inference identifies and quantifies the effect of an exposure (the hypothetical cause) to an outcome. While randomised controlled trial design is the preferred method for establishing and measu...

AbstractIntroduction. There is convincing evidence that overall adiposity increases the risks of several cancers. Whether the distribution of adiposity pla

A healthy plant-based diet might reduce the burden of multimorbidity of cancer and cardiometabolic diseases among middle-aged and older adults.

Although 10 000 steps per day can still be a viable target for those who are more active, 7000 steps per day is associated with clinically meaningful improvements in health outcomes and might be a mor...

Background: Cancer, cardiovascular diseases (CVD), and type 2 diabetes (T2D) may co-occur, a condition referred to as multimorbidity. Physical activity is inversely associated with each of these disea...

Objective To examine separate and joint associations between pre-existing cardiometabolic comorbidities and all cause and cause specific mortality in adults with cancer.Design Multinational cohort stu...

Background Obesity is influenced by a complex, multifaceted system of determinants, including the food environment. Governments need evidence to act on improving the food environment. The aim of this ...

Smoking and alcohol consumption are modifiable lifestyle risk factors for hepatocellular carcinoma. While they differentially contribute to DNA damage, proto-oncogene activation, and mitochondrial im....

Dried fruits and nuts contain high amounts of nutrients and phytochemicals—all of which may have anticarcinogenic, anti-inflammatory, and antioxidant properties. This narrative review summarizes the e...

Millennia-old genomes suggest Indo–European tongues originated from the Caucasus mountain region.

Despite strong interest in using artificial intelligence to make research faster, easier and more accessible, researchers say they need more support to navigate its possibilities.

ds: Using UK Biobank data from 462,301 adults (40–69 years at baseline: 2006–2010), we derived four body shapes from principal component analysis on body mass index, height, weight, waist and hip ci...

We are commemorating World Cancer Day by sharing a selection of Springer Nature journal articles, collections, clinical trial registrations and blog posts chosen by our publishers.

The growing impact of chronic degenerative pathologies (such as cardiovascular disease, type 2 diabetes and Alzheimer’s disease) requires and pushes towards the development of new preventive strategie...

Objective Low body fat and high physical activity levels are key lifestyle factors in cancer prevention, but the interplay of abdominal obesity and physical activity on cancer risk remains unknown. We...