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Håvard Lindholm

@havardtl.bsky.social
47 followers 125 following 4 posts

Bioinformatics, transposable elements, immunology and more! Department of Pathology, Oslo University Hospital

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Håvard Lindholm @havardtl.bsky.social · 15/09/2026
Happy to share that our review on viral mimicry is now published!
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Håvard Lindholm @havardtl.bsky.social · 20/12/2025
A PhD fellowship in our lab is available. If you or someone you know is interested in exploring how we can activate antiviral responses to kill cancer cells, please spread the word! Don't hesitate to get in touch if you have any questions. Link: www.nature.com/naturecareer...
nature.com
PhD fellowship in cancer research - Oslo, Østlandet (NO) job with Oslo University Hospital - Department of Pathology | 12851095
A fully funded three-year full-time PhD fellowship in cancer research is available at the Department of Pathology, Oslo University Hospital, Norway.
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Reposted by Håvard Lindholm
Daniel De Carvalho @daniel-decarvalho.bsky.social · 26/09/2025
Excited to have this paper out today! Repeats mimic pathogen-associated patterns across a vast evolutionary landscape." It was a fun and productive collaboration with Benjamin Greenbaum John LaCava, Simona Cocco, Petr Šulc and many others! www.cell.com/cell-genomic...
cell.com
Repeats mimic pathogen-associated patterns across a vast evolutionary landscape
An emerging hallmark of disease is transcription of pathogen-associated molecular patterns from within the genome–known as viral mimicry. We propose a statistical physics framework to measure “selecti...
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Håvard Lindholm @havardtl.bsky.social · 25/09/2025
Nice to see this story out! The idea that viral mimicry is an intrinsic feedback mechanism for sensing cellular dysregulation is fascinating and this paper explores this idea really well. It was inspiring to be part of this collaborative work. Thanks to @bengrbm.bsky.social and the rest!
cell.com
Repeats mimic pathogen-associated patterns across a vast evolutionary landscape
An emerging hallmark of disease is transcription of pathogen-associated molecular patterns from within the genome–known as viral mimicry. We propose a statistical physics framework to measure “selecti...
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Reposted by Håvard Lindholm
Research at UHN @uhnresearch.ca · 11/04/2025
Congratulations to Dr. Daniel De Carvalho (@daniel-decarvalho.bsky.social) on winning the 2025 Gairdner Momentum Award! 🎉 His impactful work in cancer epigenetics is revolutionizing early detection and treatment. A well-deserved honour! 👏 🔗 www.uhnresearch.ca/news/gairdne...
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Reposted by Håvard Lindholm
Daniel De Carvalho @daniel-decarvalho.bsky.social · 17/01/2025
Our recent work on Viral mimicry escape in Ovarian Cancer is out at Cancer Discovery: aacrjournals.org/cancerdiscov...
aacrjournals.org
Chronic viral mimicry induction following p53 loss promotes immune evasion
Abstract. Epigenetic therapies facilitate transcription of immunogenic repetitive elements that cull cancer cells through ‘viral mimicry’ responses. Paradoxically, cancer-initiating events also facili...
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