iiinova — where your digital self keeps evolving

Reposted by Hartkoorn Lab at the Institut Pasteur of Lille (France)

Olivier Neyrolles @oneyrolles.bsky.social · 20/05/2025

New study reveals how M. tuberculosis PdtaS, a constitutively active kinase, senses both copper and nitric oxide by inhibiting dimerization, not binding. A fresh twist on two-component signaling! ✍️ @michaelglickman.bsky.social and coll. 👏👏👏 📖 shorturl.at/DiWXp #Tuberculosis #MicroSky

0187

Hartkoorn Lab at the Institut Pasteur of Lille (France) @hartkoorn-lab.bsky.social · 20/05/2025

Gram-negative efflux pumps play a major role in resistance to antibiotics and impede the development of new ones. With Marion Flipo we share our Viewpoint on current and future considerations for the development of efflux pump inhibitors for Gram-negative bacterial. revive.gardp.org/crippling-gr...

revive.gardp.org

Crippling Gram-negative bacterial efflux of antibiotics - by Marion Flipo and Ruben C. Hartkoorn

PLEASE NOTE: The Viewpoints on our website are to be read and freely shared by all. If they are republished, the following text should be used: “This Viewpoint was originally published on the REVIVE w...

000

Reposted by Hartkoorn Lab at the Institut Pasteur of Lille (France)

Andreas Peschel @andreaspeschel.bsky.social · 19/05/2025

Join us in Tubingen as a Junior Research Group Leader if you do research on #ESKAPE pathogens and infections and are interested in the highly cooperative environment of @dzif.bsky.social‬ and @cmfi.bsky.social ! Please send your application or forward to colleagues! uni-tuebingen.de/universitaet...

13564

Hartkoorn Lab at the Institut Pasteur of Lille (France) @hartkoorn-lab.bsky.social · 24/03/2025

Happy World tuberculosis day! Thanks to amazing collaborations between medicinal chemistry and microbiology at @pasteurlille.bsky.social we do our best to develop novel anti-tuberculosis therapies such as through our collaborative effort on the novel antibiotic class of TricyclicSpirolactams .

1101

Reposted by Hartkoorn Lab at the Institut Pasteur of Lille (France)

WHO @who.int · 06/03/2025

Early reports to WHO from the 30 highest #tuberculosis (TB)-burden countries confirm that funding cuts from foreign aid, particularly from USAID, are already dismantling essential TB services. Without urgent action, these setbacks will reverse decades of progress to #EndTB 🔗 bit.ly/4kvsu2i

Funding cuts impact access to tuberculosis (TB) services for millions.

15644283

Reposted by Hartkoorn Lab at the Institut Pasteur of Lille (France)

Institut Pasteur | 130 years of biomedical research @pasteur.fr · 06/03/2025

Science, research & public health face unprecedented attacks in the U.S. We stand with our American colleagues & support the Stand Up for Science call. Join the global march tomorrow, incl. in Paris! 🧪✊ 📍 March 7, 13:30 – Place Jussieu 🔗 More info: standupforscience.fr #StandUpForScience

326582