High-resolution structures of the plant small GTPase RACB show how switching between inactive and active states enables RIPb effector binding, providing a physical link between the cell membrane and m...

TGF-β is a latent complex (L-TGF-β). Latency is conferred by a homodimeric prodomain with a previously undefined domain architecture. Here we define the architecture of the prodomain as domain-swapped...

Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi discovered regulatory T cells that prevent autoimmune disease

John Clarke, Michel Devoret, and John Martinis honored for work demonstrating quantum mechanical tunneling in electrical circuits

To be able to support the complex process of wound closure, a biocompatible material is required that combines suitable adhesiveness and stability with the ability to withstand certain biological chal...

VDAC2 deficiency elicits uncontrolled IFNγ-induced BAK activation and mitochondrial damage for improved cancer therapy.

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