dlvr.it
Spatial proteomics identifies a CRTC-dependent viral signaling pathway that stimulates production of interleukin-11
Ravenhill et al. employ subcellular proteomics to quantify the movement of >9,000 proteins during infection with the model RNA virus Sendai. In addition to known controls, CRTC2 and CRTC3 translocate to the nucleus, triggering a transcriptional program…