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Guim Aguadé-Gorgorió @guimaguade.bsky.social · 14/10/2026

Could we take advantage of the complex multispecies interactions of soil microbiomes and engineer their capacity to sustain ecosystem function? To study this, we couple microbial dynamics to the desired spread of new functions in a new paper led by @vmaull.bsky.social

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Reposted by Guim Aguadé-Gorgorió

Systems Ecology @systems-ecology.bsky.social · 21/09/2026

🌱 Systems Ecology is now live! A new independent, researcher-run, diamond OA journal for ecological research through systems science. Free to read. Free to publish. No APCs. We are now open for submissions: systems-ecology.org Please help spread the word!

systems-ecology.org

Systems Ecology

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Guim Aguadé-Gorgorió @guimaguade.bsky.social · 18/09/2026

This looks promising! "...free to read and free to publish, with no subscription barriers for readers and no article processing charges for authors. The journal is run by researchers, for researchers, with the goal of advancing ecology through systems thinking."

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Reposted by Guim Aguadé-Gorgorió

Richard McElreath 🐈‍⬛ @rmcelreath.bsky.social · 02/09/2026

Last year, I publicly complained multiple times (see e.g. elevanth.org/blog/2025/07...) that the open access movement had been captured by publishers, and we are now worse off than before open access. Well people got mad at me for saying it. But I think things are still getting worse.

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Reposted by Guim Aguadé-Gorgorió

Ricard Solé @ricardsole.bsky.social · 29/06/2026

What is a disease? In our new concept paper, we explore how complex networks, statistical physics, phase transitions and attractors allow us to redefine diseases as multiscale, emergent dynamical states. @manlius.bsky.social @guimaguade.bsky.social www.preprints.org/manuscript/2...

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Guim Aguadé-Gorgorió @guimaguade.bsky.social · 15/06/2026

What can spatial patterns tell us about tumor growth or dryland ecosystem resilience? Are there bridges and opportunities between these apparently distant disciplines? This wednesday June 17 we'll have the 3rd Session of Eco-Onco Exchange, with @joshuabull.bsky.social and Benoît Pichon !

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Guim Aguadé-Gorgorió @guimaguade.bsky.social · 10/06/2026

So glad to be back at @sfiscience.bsky.social , catching up with old friends and presenting recent work on microbial communities! www.santafe.edu/events/semin...

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Guim Aguadé-Gorgorió @guimaguade.bsky.social · 22/05/2026

a great and useful framework - yet, how can we incorporate multistability? if a given set of conditions does not yield one community state, but multiple, how robust are the methods against empirical confrontation?

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Guim Aguadé-Gorgorió @guimaguade.bsky.social · 22/04/2026

This is today! looking forward to hearing Jesus' and Onofrio's talks on growth models

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Guim Aguadé-Gorgorió @guimaguade.bsky.social · 13/04/2026

How do tumors or bacteria modulate their environment, and how does that translate into their growth? What can we learn from maths, and what are the implications for cancer therapy or ecosystem resilience? Register here for the first Eco-Onco session, April 22nd forms.gle/B77tZmyzCzmp...

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Guim Aguadé-Gorgorió @guimaguade.bsky.social · 07/04/2026

Microbial communities can harbor many species that do not coexist in pairs, yet can coexist in the full community. Here we provide the mathematical foundations of emergent coexistence, and explain why it can't be predicted from pairwise tests journals.plos.org/ploscompbiol...

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Guim Aguadé-Gorgorió @guimaguade.bsky.social · 30/03/2026

Very interesting! Although different, models of multi-species competition such as the generalized Lotka-Volterra model also produce very rugged attractor landscapes, that are not quite consistent with simpler successional trajectories between a few states - could a similar process operate?

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Guim Aguadé-Gorgorió @guimaguade.bsky.social · 19/03/2026

The first Eco-Onco Exchange seminar has been postponed by one week, to Apr 22nd! Register here: forms.gle/B77tZmyzCzmp...

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Guim Aguadé-Gorgorió @guimaguade.bsky.social · 17/03/2026

Excited to announce Eco-Onco Exchange — a virtual seminar series bridging mathematical ecology and oncology. Each session pairs two speakers from each field around a shared theme, followed by joint discussion. First three sessions coming soon! Register here docs.google.com/forms/d/e/1F...

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Guim Aguadé-Gorgorió @guimaguade.bsky.social · 05/03/2026

Similar tumors can often respond very differently to immunotherapy. Why? A simple mathematical model reveals the possibility of two alternative evolutionary strategies, dictated by mutational loads www.sciencedirect.com/science/arti...

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Guim Aguadé-Gorgorió @guimaguade.bsky.social · 17/02/2026

@vmaull.bsky.social plasmid promiscuity through HGT + competition against non-promiscuous individuals = even more spreading? www.biorxiv.org/content/10.1...

biorxiv.org

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Reposted by Guim Aguadé-Gorgorió

Institut Natura e Teoria ※ Pireneus (INTP) @intp-science.bsky.social · 28/01/2026

☀️ 2026 Summer School in the Pyrenees - Unifying Mathematical Models of Biodiversity Applications are now open! This school offers a state-of-the-art overview for interdisciplinary theoreticians. 🗓️ July 5-11 🎯 PhD students to senior researchers ℹ️ intp.science/en/summer26.... 📭 contact@intp.science 🌐🧪

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Reposted by Guim Aguadé-Gorgorió

Ricard Solé @ricardsole.bsky.social · 06/02/2026

Excited to share a new PhD thesis from my student and soon Dr @vmaull.bsky.social on synthetic ecosystems, preventing tipping points, and a new concept: emergent bioengineering. Very proud of this achievement, and thankful to @sfiscience.bsky.social, where many of these ideas came to life.

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Reposted by Guim Aguadé-Gorgorió

Ricard Solé @ricardsole.bsky.social · 19/12/2025

Cooperation is a universal feature of complex systems, from the origins of life and microbiomes to societies. What universal patterns can be found in these systems? Here's our new @pnas.org paper. @jordipinero.bsky.social @artemyte.bsky.social @sfiscience.bsky.social www.pnas.org/doi/epdf/10....

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Reposted by Guim Aguadé-Gorgorió

Ricard Solé @ricardsole.bsky.social · 31/10/2025

Why do some cancers respond to immunotherapy while others don’t? A new paper by @guimaguade.bsky.social shows, using maths, that as tumors mutate, they face a trade-off: growing faster can also make them easier for the immune system to spot. @sandyanderson.bsky.social www.biorxiv.org/content/10.1...

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Reposted by Guim Aguadé-Gorgorió

Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 24/09/2025

Who is afraid of HGT? True, antibiotic resistances disseminate through it. But we can also leverage the same channels for spreading good stuff at a very large scale and fortifying the env microbiome with beneficial activities www.biorxiv.org/content/10.1... by Victor Maull & @ricardsole.bsky.social

biorxiv.org

Synthetic Horizontal Gene Transfer for Ecosystem Restoration

Restoring endangered ecosystems has become a pressing issue as the effects of global warming continue to harm existing communities. Over the last decade, several studies have suggested the use of synt...

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Reposted by Guim Aguadé-Gorgorió

Ricard Solé @ricardsole.bsky.social · 24/09/2025

Can synthetic biology help save endangered ecosystems? Our new paper with @vmaull.bsky.social explores how engineered genes can spread through soil microbes. We model how synthetic gene transfer can support biodiversity. @vdlorenzo.bsky.social @guimaguade.bsky.social www.biorxiv.org/content/10.1...

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Reposted by Guim Aguadé-Gorgorió

DIFENSC - RSEF @difensc-rsef.bsky.social · 23/09/2025

We are so close to start the @cs3conference.bsky.social Spainish Chapter (CS3) School !! 🎉 One of our invited talks will be delivered by Guim Aguadé-Gorgorió @guimaguade.bsky.social , about a really fascinating topic 👇

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Guim Aguadé-Gorgorió @guimaguade.bsky.social · 12/09/2025

A central finding is that, even if we could measure pairwise interactions up to a certain precision, strong indirect effects can make our efforts useless: at high collectivity, pairwise interactions no longer inform about community coexistence www.biorxiv.org/content/10.1...

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Guim Aguadé-Gorgorió @guimaguade.bsky.social · 13/08/2025

Some tumors with many mutations are eliminated by immunotherapy, while others evade immune surveillance and eventually relapse. A new mathematical model could help us understand the complex role of mutational load in immunotherapy resistance www.biorxiv.org/content/10.1... @ricardsole.bsky.social

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Guim Aguadé-Gorgorió @guimaguade.bsky.social · 02/06/2025

Immunotherapy fails at curing heterogeneous cancers. Why? Modeling and clinical data suggest a limit to tumor heterogeneity, beyond which T cells fail at controlling highly-diverse tumors. Can we take advantage of this limit? @ricardsole.bsky.social royalsocietypublishing.org/doi/full/10....

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Guim Aguadé-Gorgorió @guimaguade.bsky.social · 22/05/2025

Our work is based on two great recent articles that strongly impacted the way I think about complexity in ecology. Inspiring! @changyuchang.bsky.social @asanchezlab.bsky.social

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Guim Aguadé-Gorgorió @guimaguade.bsky.social · 20/05/2025

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Guim Aguadé-Gorgorió @guimaguade.bsky.social · 31/01/2025

I've used this paper quite a lot and we've discussed with @ricardsole.bsky.social and @vmaull.bsky.social often. Great and useful work!

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Guim Aguadé-Gorgorió @guimaguade.bsky.social · 27/01/2025

Super interesting! reminds me of the work by I. Martincorena, finding that epidermic cells can remain healthy even when carrying hundreds of cancer mutations www.science.org/doi/abs/10.1... Maybe genome alterations are not enough and other ecological dynamics play a role?

science.org

High burden and pervasive positive selection of somatic mutations in normal human skin

Sun-exposed but physiologically normal human skin harbors an unexpectedly high number of cancer-causing mutations. [Also see Perspective by Brash]

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Guim Aguadé-Gorgorió @guimaguade.bsky.social · 22/01/2025

Thanks! In the paper we mention some ongoing efforts in that direction, but it does still feel a bit futuristic. On my side, I am very interested on the cancer-immune-microbiome ecosystem that you work in! Would love to chat about it at some point :D

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Guim Aguadé-Gorgorió @guimaguade.bsky.social · 13/01/2025

Tumors harbor hundreds of different cell types that compete and cooperate, mirroring a natural ecosystem. Can we model cancer as a complex ecosystem of many interacting species? An honor to work w/ @ricardsole.bsky.social and Sandy Anderson while bringing in recent work in ecology with Sonia Kéfi!

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