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Berkley Gryder

@gryderart.bsky.social

61 followers 23 following 4 posts

Childhood Cancer Epigenetics and Drug Discovery Assistant Prof. at Case Western Reserve University gryderlab.com

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Reposted by Berkley Gryder

Matt Hall @cispt2.bsky.social · 13/02/2025

New paper in Nature Comms with Isaac Brownell NIAMS, identifying #repurposing treatment options for the rare Merkel Cell Carcinoma (MCC). We found Aurora kinase criticality in genetic & chemogenomic screens - wonderful collaboration @gryderart.bsky.social #NCATS www.nature.com/articles/s41...

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Berkley Gryder @gryderart.bsky.social · 10/12/2024

spectacular work! I love this paper SO much!

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Berkley Gryder @gryderart.bsky.social · 01/12/2024

yes this Orlando et al paper is the one with my vote. ChIP-Rx!

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Berkley Gryder @gryderart.bsky.social · 21/11/2024

Proud of my collaborator @KidCancerLab for discovering how wound healing programs promote lung metastasis! "Aberrant activation of wound healing programs within the metastatic niche facilitates lung colonization by osteosarcoma cells" aacrjournals.org/clincancerre...

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Berkley Gryder @gryderart.bsky.social · 19/11/2024

Our story in PNAS today! (1) anti-AR molecules with new mechanism: induction of chromatin binding YET a disruption of transcription (2) why only ~150 genes respond to AR ligands, despite the 6,000+ AR binding sites: they need 3D clustering to matter! www.pnas.org/doi/10.1073/pnas.2406239121

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