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GcL

@grosscol.bsky.social
443 followers 152 following 267 posts

Programming and human genetics. Working with TOPMED data and providing a view into human variation via BRAVO (bravo.sph.umich.edu)

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GcL @grosscol.bsky.social · 13h
Seems like a very Basic question.
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GcL @grosscol.bsky.social · 28/09/2026
Classic Reynolds
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GcL @grosscol.bsky.social · 27/09/2026
The maffs add up.
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GcL @grosscol.bsky.social · 23/09/2026
Hard for the healthcare insurance industry.
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GcL @grosscol.bsky.social · 21/09/2026
I enjoy inkscape. I use it to create SVGs for a web interface that uses D3 to manipulate them.
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GcL @grosscol.bsky.social · 18/09/2026
I haven't played since 3rd edition, but I feel like I really understand the howling mine now.
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GcL @grosscol.bsky.social · 18/09/2026
Patreon members
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GcL @grosscol.bsky.social · 11/09/2026
We call that "crafternoon" or "crafterevening" around here. We all bring our favorite paper/clay/fabric/art things.
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GcL @grosscol.bsky.social · 09/09/2026
Jean Claude Van Damn It!
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GcL @grosscol.bsky.social · 07/09/2026
Fucking bananas
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GcL @grosscol.bsky.social · 05/09/2026
Unhinged! Inane! Funny! Also, yeah people should clean up after their dogs. Dogs are the best people after all.
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GcL @grosscol.bsky.social · 01/09/2026
Isn't that how baldness treatments and dick pills are distributed these years? There's a distinct lack of outrage or even concern there.
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GcL @grosscol.bsky.social · 01/09/2026
Seems like murdering Illinois residents in Illinois is the kind of thing where Illinois should have arrested, investigated, and prosecuted the perpetrators.
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GcL @grosscol.bsky.social · 29/08/2026
To be fair, in those mytholgies the omniscient dieties are also idiots that fuck up.
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GcL @grosscol.bsky.social · 29/08/2026
Filling up /var/log has got to be one of the most mundane and unsatisfying experiences that still sets you apart from most users.
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GcL @grosscol.bsky.social · 28/08/2026
If the collateral damage didn't include children and other vulnerable folks, I would agree. It's so much more infuriating when the stupidity of someone doesn't just affect themselves and the other stupids.
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GcL @grosscol.bsky.social · 28/08/2026
Remember folks, there's no thought too stupid for a person to have. Also, you can mock those people using comics!
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GcL @grosscol.bsky.social · 26/08/2026
Silver lining I guess.
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GcL @grosscol.bsky.social · 26/08/2026
I would agree if there wasn't so much collateral damage. Worse yet, most of the fallout of adults poor choices hits children.
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GcL @grosscol.bsky.social · 26/08/2026
There is no thought too unhinged for a person to have, and apparently illustrate. Thank you.
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GcL @grosscol.bsky.social · 20/08/2026
Radish in a burrito?! That's crazy.
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GcL @grosscol.bsky.social · 15/08/2026
Is posting this AI slop intentional irony?
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GcL @grosscol.bsky.social · 13/08/2026
I'm looking forward to your correction/edit to the cartoon.
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GcL @grosscol.bsky.social · 13/08/2026
Neat. Add that to the plot.
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GcL @grosscol.bsky.social · 13/08/2026
Somewhere near the axis. Are you giving an entertaining cartoon the same consideration as a figure in a scientific publication? If so, what's the underlying mathematical model we're interrogating?
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GcL @grosscol.bsky.social · 13/08/2026
I assume the mass loss approaches 100% and the black hole evaporates entirely. The event horizon shrinks to zero.
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GcL @grosscol.bsky.social · 13/08/2026
Start with a slightly bigger one and let it evaporate. How you get one in our current time frame would be an actual conundrum.
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GcL @grosscol.bsky.social · 12/08/2026
Is this, "If you don't have actual intelligence, store bought is fine."
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GcL @grosscol.bsky.social · 11/08/2026
Trying to be a better asshole is still a shitty thing.
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GcL @grosscol.bsky.social · 07/08/2026
I have been expressing my view of AI succinctly as: "The direct, indirect, and knock on cost of generative ai are not worth the benefit."
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GcL @grosscol.bsky.social · 06/08/2026
Some big name actors detract from roles, as they're at a stage where they mainly play their brand with a bit of the character's flavor sprinkled on.
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GcL @grosscol.bsky.social · 04/08/2026
The idea that our brains contain a "lizard brain" is like saying your car engine contains a Model-T engine. Your modern engine has a lot of parts strikingly similar to other models of combustion engines, but you can't strip down your car and find a Model-T.
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GcL @grosscol.bsky.social · 03/08/2026
This is the kind of WTF that I should be experiencing instead of... well... you know.
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GcL @grosscol.bsky.social · 30/07/2026
Sorry that all of that happened to you. Those rose colored glasses might be her way of protecting herself. The truth hurts and many people don't have the tools to process it. I do sometimes miss my old rose colored glasses. They were heart shaped.
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GcL @grosscol.bsky.social · 29/07/2026
What flavor is traditional for ice cream post ass kicking?
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GcL @grosscol.bsky.social · 20/07/2026
Looks like ai slop
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GcL @grosscol.bsky.social · 20/07/2026
Looks like ai slop.
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GcL @grosscol.bsky.social · 20/07/2026
Unhinged, entertaining, and ten thousand percent true.
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GcL @grosscol.bsky.social · 09/07/2026
I concur. The old familiar dependency hell is better than the new dependency hells.
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GcL @grosscol.bsky.social · 07/07/2026
Orphan works were the crux of the authors guild vs hathi trust. Turns out the authors guild doesn't implicitly represent the putative copyright holders of orphan works.
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GcL @grosscol.bsky.social · 06/07/2026
Do a barrel roll.
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GcL @grosscol.bsky.social · 05/07/2026
I heard you were six foot twenty and weigh a mother fucking ton.
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GcL @grosscol.bsky.social · 04/07/2026
It's the Gish Gallop
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GcL @grosscol.bsky.social · 04/07/2026
You tell them what they already know. It's the price they pay for all the unconditional love, affection, and companionship that they give and get in return. And then remind them that they're strong enough to do it again, because the next one deserves it just as much.
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GcL @grosscol.bsky.social · 03/07/2026
All text must now be alt text.
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GcL @grosscol.bsky.social · 03/07/2026
I heard Gatsby Reeps saved the day on more than one occasion
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GcL @grosscol.bsky.social · 03/07/2026
Holes.
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GcL @grosscol.bsky.social · 02/07/2026
Hopefully those countries also get in on developing and maintaining the upstream as well.
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GcL @grosscol.bsky.social · 27/06/2026
I like the code review gauntlet in the back as well.
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GcL @grosscol.bsky.social · 24/06/2026
Got 'em with the deliciousness.
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