Early-life exposure to allergens triggers a distinct local mode of dendritic cell activation in neonatal skin without requiring migration to lymph nodes, which shapes responses to allergens in later l...

Novak et al. discover that dietary serine impacts whether hair follicle stem cells (HFSCs) prioritize hair growth or skin repair after injury. HFSCs gauge metabolic stress using the ISR and accelerate...

Adult stem cells self-renew and differentiate to build, maintain and repair tissues. This Review discusses recent insights into the contribution of mechanical forces produced by epithelial stem cell a...

Nature Reviews Molecular Cell Biology, Published online: 29 January 2025; doi:10.1038/s41580-024-00821-0Adult stem cells self-renew and differentiate to build, maintain and repair tissues. This Review discusses recent insights into the contribution of…