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Graeme Cowan 🧬👨🏻‍💻

@graemecowan.bsky.social
603 followers 772 following 15 posts

Immunologist at University of Edinburgh working in B and T cells in infection (malaria) and autoimmunity (rheumatoid arthritis). I use NGS, computational biology, single cell approaches and Adaptive Immune Receptor Repertoire seq👨🏻‍💻🧬🦠🧫

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Graeme Cowan 🧬👨🏻‍💻 @graemecowan.bsky.social · 31/05/2025
Why do B cells make (more) cochlin in RA, SLE and Sjogrens? A really interesting preprint, from @beccabelmonte.bsky.social and Mohini Gray at @edinuni-irr.bsky.social www.biorxiv.org/content/10.1...
biorxiv.org
Cochlin-Expressing Memory B (COMB) Cells Are Enriched in Autoimmune Diseases and Display a Distinct Activation Profile
Rheumatoid arthritis (RA) is the most common chronic autoimmune arthritis, causing joint damage and affecting multiple organs over time. B cells play a key role in driving the disease by producing aut...
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Graeme Cowan 🧬👨🏻‍💻 @graemecowan.bsky.social · 31/05/2025
Really enjoyed reading this preprint from Emma Davenport and Marina Botto’s labs. scRNAseq + AIRR of rituximab treatment in SLE - www.medrxiv.org/content/10.1...
medrxiv.org
Single-cell level characterization of B cell depletion and repopulation following rituximab in systemic lupus erythematosus
Objective Rituximab, a CD20+ B cell depletion therapy, is frequently used in the treatment of systemic lupus erythematosus (SLE). However, variability in patient response highlights the need for a dee...
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Reposted by Graeme Cowan 🧬👨🏻‍💻
Nikhil Garg @nkgarg.bsky.social · 10/03/2025
*Please repost* @sjgreenwood.bsky.social and I just launched a new personalized feed (*please pin*) that we hope will become a "must use" for #academicsky. The feed shows posts about papers filtered by *your* follower network. It's become my default Bluesky experience bsky.app/profile/pape...
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Reposted by Graeme Cowan 🧬👨🏻‍💻
Perona Lab, Edinburgh, UK @peronalab.bsky.social · 03/03/2025
I'm very pleased to have two lab positions open this week, to join our team looking at immune regulation in infection and co-infection. We're especially interested in tissue-based immunity, cytokine regulation and immune metabolism. Join us! Postdoc (3y) and research technician (12mo) posts open.
We're based in the Ashworth Laboratories, King's Buildings, University of Edinburgh. Photo shows the main staircase in the entrance to the Ashworth, stone steps from the 1920s, decorated with a series of bright, colurful banners depicting the science that's tackled in the building.
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Reposted by Graeme Cowan 🧬👨🏻‍💻
Perona Lab, Edinburgh, UK @peronalab.bsky.social · 24/02/2025
Our search for a flow cytometry core facility manager for King's Buildings, University of Edinburgh, is finally live. Join us! Conventional & spectral. Parasites, immune cells, algae, bacteria, yeast and more. Full-time, open-ended. Apply by 17 March. elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
elxw.fa.em3.oraclecloud.com
Flow Facility Manager
We are looking for a facility manager for the SBS flow cytometry core facility. This is a full-time position (35 hours per week) with most of that time expected to be on campus in the flow facility. W...
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Graeme Cowan 🧬👨🏻‍💻 @graemecowan.bsky.social · 17/02/2025
Our new publication on BCR sequencing in ME/CFS, adding to the evidence of an increased usage of IGHV3-30. Much more immunological research is needed to understand the many lines of evidence indicating immune-mediated or autoimmune components to the disease. www.frontiersin.org/journals/imm...
frontiersin.org
Frontiers | Deep sequencing of BCR heavy chain repertoires in myalgic encephalomyelitis/chronic fatigue syndrome
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Graeme Cowan 🧬👨🏻‍💻 @graemecowan.bsky.social · 10/12/2024
It’s wonderful to be at the University of Glasgow today to examine a viva. I think the last time I was here was 18 years ago for my own.
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Graeme Cowan 🧬👨🏻‍💻 @graemecowan.bsky.social · 26/11/2024
Having a day back in the lab expressing antibodies in Expi293 cells. Very excited to use my new 3d printed flask holder- much better than the old sticky mat!
Erlenmeyer tissue culture flasks on a shaking platform in a tissue culture incubator.
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Graeme Cowan 🧬👨🏻‍💻 @graemecowan.bsky.social · 26/11/2024
Looking forward to this- just registered.
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Graeme Cowan 🧬👨🏻‍💻 @graemecowan.bsky.social · 20/11/2024
Welcome to BlueSky @uoe-eid.bsky.social !
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Reposted by Graeme Cowan 🧬👨🏻‍💻
Jamie Heather @jamieheather.bsky.social · 18/11/2024
Inspired by @rodrahimi.bsky.social 's noble efforts linking immunologists together over here, let's try and get more specifically TCR/BCR/AIRR/repertoire chat going with this starter park go.bsky.app/Gi2dcGd Drop me a beep to get added or suggest others!
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