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Shane Gonen

@gonenshane.bsky.social
1.5K followers 1K following 14 posts

Assistant Professor, University of California Irvine. All opinions my own #CryoEM #ProteinDesign #Biochemistry #MembraneProteins #UCI cryoem.bio.uci.edu

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Reposted by Shane Gonen
Ribbe Hu Labs @ribbehulab.bsky.social · 18/10/2025
Our home department of Molecular Biology & Biochemistry at UC Irvine is looking to hire a new tenure-track assistant professor in the broad area of structural biology. Come be our colleague! recruit.ap.uci.edu/JPF09887 Please apply and/or share this post.
recruit.ap.uci.edu
Assistant Professor in Structural Biology and Biochemistry, Department of Molecular Biology & Biochemistry
University of California, Irvine is hiring. Apply now!
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Reposted by Shane Gonen
Dequina Nicholas @quinascience.bsky.social · 06/05/2025
Herculean effort by the Wiles lab @UCIBioSci Congrats to the entire team and the first author postdoc Liz for this amazing cover art! Proud of #Nicholaslab members Naveena and Julio for the small role we played in this groundbreaking work
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Reposted by Shane Gonen
Liz Ortiz de Ora @ortizdeora.bsky.social · 06/05/2025
We’re thrilled to be featured on the May cover of Nature Microbiology... And our Research Briefing is out now—check it out, it’s 🔥! www.nature.com/articles/s41...
nature.com
‘Phollowing’ phage outbreaks in microbiomes with live fluorescence microscopy - Nature Microbiology
Phollow is an in vivo tagging approach for marking bacteriophages with fluorescent proteins while new virions are assembled in bacteria, enabling direct observation of phage outbreaks with single-viri...
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Reposted by Shane Gonen
Nature Microbiology @natmicrobiol.nature.com · 06/05/2025
"Phollow" the link to our May issue to read about... 💥lysing bacterial pathogens ⛽microbial alkane oxidation 🌱importance of seed-borne bacteria 🙅‍♀️protective antibodies for norovirus 🚰E. coli in urban drinking water ...and more!👇 www.nature.com/nmicrobiol/v...
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Shane Gonen @gonenshane.bsky.social · 19/04/2025
Beautiful new work from our colleagues down the hall 🔬🥂
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Shane Gonen @gonenshane.bsky.social · 07/02/2025
Our #CryoEM study on the binding of a Tarantula toxin to a full-length human voltage-gated sodium channel has been published. Very proud of the awesome people in my lab 🥳🥂 www.nature.com/articles/s41...
nature.com
Structural basis of inhibition of human NaV1.8 by the tarantula venom peptide Protoxin-I - Nature Communications
Animal toxins can modulate action potentials and are important leads for therapeutics. Here, the authors use cryo-EM to show the interaction of the tarantula venom peptide Protoxin-I with a human volt...
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Shane Gonen @gonenshane.bsky.social · 01/02/2025
buckle up out there
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Reposted by Shane Gonen
Justin English @justingenglish.bsky.social · 02/01/2025
Groundbreaking work by @matthewkhoward.bsky.social and Nicholas Hoppe (not on bsky?) from the @willowcoyote.bsky.social @amanglik.bsky.social labs. Mapping function to structure with deep mutational scanning to resolve the mechanisms of pH sensing GPCRs www.sciencedirect.com/science/arti...
sciencedirect.com
Molecular basis of proton sensing by G protein-coupled receptors
Three proton-sensing G protein-coupled receptors (GPCRs)—GPR4, GPR65, and GPR68—respond to extracellular pH to regulate diverse physiology. How proton…
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Reposted by Shane Gonen
Ute Hellmich @hellmichgroup.bsky.social · 16/11/2024
Ok, trying to bring my community back together... I created a starter pack for lipids and membrane protein aficionados! Feel free to share, add and distribute, so we can come together again! 😍 go.bsky.app/AEeXh86
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Shane Gonen @gonenshane.bsky.social · 27/11/2024
I see 2 dolphins and a croc image from not #cryoem
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Shane Gonen @gonenshane.bsky.social · 19/11/2024
#cryoem grids don't have to be 3mm do they?
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Reposted by Shane Gonen
Rémi Fronzes @fronzeslab.bsky.social · 08/11/2024
Here is a starter pack for CryoEM/ET enthousiasts To be completed go.bsky.app/JmQksC
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