iiinova — where your digital self keeps evolving

giovannilandoni.bsky.social @giovannilandoni.bsky.social · 08/08/2025

this is a materpiece by the young and brilliant @filippodamico.bsky.social everything you know about blood pressure targets is from (old) animal studies and different animals have different thresholds! freely availbale on @signavitaejournal.bsky.social

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Signa Vitae @signavitaejournal.bsky.social · 13/07/2025

Our latest issue contains a editorial by our Editor-in-Chief @giovannilandoni.bsky.social and @martinabaiardo.bsky.social about Prof. Rinaldo Bellomo, a great scientist and physician that inspired many, but sadly passed away this year www.signavitae.com/articles/10.22514/sv.2025.091

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giovannilandoni.bsky.social @giovannilandoni.bsky.social · 05/08/2025

Published today! #MICROCLOTS in the lungs of #ARDS patients a well-recognized phenomenon among senior experts (unknown by the rest till #COVID19 ) important clinical implications link to the article pubmed.ncbi.nlm.nih.gov/40754474/

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Signa Vitae @signavitaejournal.bsky.social · 02/08/2025

Reads the full article at: 🔗 www.signavitae.com/articles/10....

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Signa Vitae @signavitaejournal.bsky.social · 02/08/2025

💉 Regional anesthesia is revolutionizing cardiothoracic surgery! Reducing opioids speeds recovery and improves outcomes Paravertebral blocks, erector spinae blocks, and wound catheter anesthesia are becoming the go-to for pain management 💊Less opioid = less side effects!

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Signa Vitae @signavitaejournal.bsky.social · 31/07/2025

⏱️ Time is muscle in cardiac emergencies! In conditions like MI, arrhythmias, and heart failure, every minute counts Early recognition + rapid intervention = better outcomes Read more on timely interventions in our latest review: www.signavitae.com/articles/10.22514/sv.2025.093 #CardiacEmergency

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Signa Vitae @signavitaejournal.bsky.social · 18/07/2025

We finally landed also on Instagram! We are a peer-reviewed, open access, journal about Anesthesia, Intensive care, Emergency and Pain Medicine. 👉 Follow us today and help shape the future of critical care! Find more about us at www.signavitae.com

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Signa Vitae @signavitaejournal.bsky.social · 21/07/2025

STOP WASTING TIME YOU COULD USE DOING RESEARCH! Just upload your files when you are submitting the manuscript. Don't worry about typesetting rules or a specific reference style, you can submit your manuscript to Signa Vitae in any format of your choice

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Signa Vitae @signavitaejournal.bsky.social · 23/07/2025

🚨Solid organ transplant patients in the ED? 🩺Don’t miss this comprehensive update on diagnosis, infection management, drug interactions & organ-specific pitfalls A must-read for emergency & acute care teams 🔗 www.signavitae.com/articles/10.22514/sv.2025.092 #TransplantMedicine #EmergencyMedicine

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Signa Vitae @signavitaejournal.bsky.social · 27/06/2025

💉 Safer sedation in obese patients! Remimazolam + Sufentanil outperforms Propofol in painless colonoscopy: 🔻 Less apnea (26% vs 50%) 🔻 Less hypoxemia (32% vs 66%) 🔻 Less injection pain (8% vs 34%) 🔗 www.signavitae.com/articles/10.22514/sv.2024.085 #Anesthesia #SignaVitae

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Signa Vitae @signavitaejournal.bsky.social · 29/06/2025

Follow us on all other social media X: x.com/MRE_signavitae LinkedIn: www.linkedin.com/company/signa-vitae Facebook: www.facebook.com/profile.php?id=100064149758501

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Signa Vitae @signavitaejournal.bsky.social · 16/06/2025

🫁 What really defines ventilator-associated pneumonia in critically ill children? 👉 This narrative review compares current clinical and epidemiological definitions, aiming to support more accurate diagnosis and surveillance 🔗 www.signavitae.com/articles/10.22514/sv.2023.050 #ICU #Ventilation

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Signa Vitae @signavitaejournal.bsky.social · 18/06/2025

🫁Is Direct Laryngoscopy better than Direct+Video Larygoscopy? 🥼96 residents tried the different approaches with different results ‼️ You may find the results unexpected 🔗 signavitae.com/articles/10.22514/sv.2023.053 #AirwayManagement #SignaVitae #MedEd #FOAMed

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Signa Vitae @signavitaejournal.bsky.social · 19/06/2025

🚨 #BackPain? There’s a smarter way to treat it 💊A new review shows how combining Dexketoprofen + Tramadol can relieve pain fast while reducing the need for strong opioids A smarter, safer approach to acute pain 🔗 www.signavitae.com/articles/10.22514/sv.2025.078 #PainManagement #SignaVitae #MedEd

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JAMA @jama.com · 15/06/2025

Authors, editors, reviewers, and other potential users should use CONSORT 2025 when writing and evaluating manuscripts of randomized trials to ensure that trial reports are clear and transparent. Learn more in this Special Communication. ja.ma/3TlnKQe

CONSORT 2025 Statement
Updated Guideline for Reporting Randomized Trials

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Ed @notdred.bsky.social · 14/06/2025

Me as a kid reading Dune: I don’t get why their whole society is built around the eradication of A.I., seems like they’re wasting a lot of tech Me as an adult: oh that’s why

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Signa Vitae @signavitaejournal.bsky.social · 09/06/2025

Today our Editor-in Chief, Professor Giovanni Landoni , had a lecture with @nejm.org Editor-in-Chief, Professor Eric Rubin, organised by Unisr in Milan, Italy

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Signa Vitae @signavitaejournal.bsky.social · 13/06/2025

👑Live from #CCR25 the #Princetrial 🫀Does remote ischemic preconditioning reduce troponin levels after surgery? A preview on the matter is in #signavitae 🔗 www.signavitae.com/articles/10.22514/sv.2024.151 @giovannilandoni.bsky.social @mmarmiere.bsky.social

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Signa Vitae @signavitaejournal.bsky.social · 12/06/2025

🩸#ANHtrial results are live #CCR25 A survey from the authors: www.signavitae.com/articles/10.22514/sv.2025.076

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Critical Care Reviews @criticalcarereviews.com · 12/06/2025

ANH trial Results: In patients undergoing elective cardiac surgery, acute normovolaemic haemodilution, compared with usual care, did not reduce the number of patients requiring blood transfusion during their hospital stay. #CCR25

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https://t.co/c9eA8EyHdt

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NEJM.org @nejm.org · 12/06/2025

Presented at #CCR25: In the ANH phase 3 trial involving adult patients undergoing elective cardiac surgery, acute normovolemic hemodilution did not reduce the number of patients receiving allogeneic red-cell transfusion. Full trial results: nej.md/3FxdMrW @criticalcarereviews.com

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giovannilandoni.bsky.social @giovannilandoni.bsky.social · 12/06/2025

O2O2O2O2O2O2O2O2 o2o2o2o2o2o2o2o2 oxygen is 21% of what you breath, wherever you are (underground or climbing an high mountain, crowded room or in a forest) with the notable exception of H (mainly ICU) and with a surprising ignorance of which % is the best @criticalcarereviews.com

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Critical Care Reviews @criticalcarereviews.com · 23/05/2025

🚨 Just 20 days to #CCR25! 12 major trial results in our unique long form format ➡️ Independent editorials & panel discussions ➡️ Clinical impact of these results explored ➡️ Join us in person or virtually (free livestream or paid if you want CPD/CME) criticalcarereviews.com/meetings/ccr25

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Critical Care Reviews @criticalcarereviews.com · 23/05/2025

🚨 FLUID Trial Results🚨 Balanced crystalloids vs saline in hospitalised patients 📍 16 Canadian hospitals 👥 >144,000 pts 😮 🏁 Cluster-crossover RCT 📊 90-day death or readmission ➡️ Big trial ! ➡️ Big numbers ! 🚩 The answer drops at #CCR25🚩

Flyer for the FLUID trial results at CCR25

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Critical Care Reviews @criticalcarereviews.com · 24/05/2025

🚨 ENCOMPASS TRIAL Results at #CCR25🚨 📍 8 hospitals 👥 4032 patients 📊 Stepped-wedge cluster RCT 🎯 Tests STAR: nurse-led, telehealth care for high-risk sepsis survivors 🩺 Outcomes: 90-day readmission or death 📺 Free livestream — but it’s better in person!

Flyer for the ENCOMPASS trial results session at CCR25, investigating a nurse-led, care for high-risk sepsis survivors

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Critical Care Reviews @criticalcarereviews.com · 25/05/2025

🚨 RESCUE 3 TRIAL Results 🚨 📍 33 sites 🇺🇸🇫🇷🇩🇪 👥 n=223 📊 Open-label RCT 🎯 Lungpacer diaphragm pacing after ≥2 weaning attempts & ≥96h MV 🩺 Outcome: Successful weaning by D30 🤔 Is this the future of mechanical ventilation? 📺 Free livestream, but it's better in person

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Critical Care Reviews @criticalcarereviews.com · 25/05/2025

In memory of professor Rinaldo Bellomo: A giant of intensive care medicine CCR Journal Watch - tracking the critical care literature daily doi.org/10.1016/j.ccrj.2025.100110

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Critical Care Reviews @criticalcarereviews.com · 31/05/2025

🚨UK-ROX TRIAL Results at #CCR25🚨 📍 ~100 🇬🇧 ICUs 👥 ~16,500 pts 🎯 Conservative vs usual oxygen therapy in invasively ventilated adults 🩺 Outcome: Mortality day 90 🤔 Will less oxygen save lives? 📺 Free livestream — but it's better in person! 🔗 criticalcarereviews.com/ccr25

Flyer for the UK-ROX trial results presentation at #CCR25

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Yuki Kotani, MD @yukikotani.bsky.social · 27/05/2025

🩸 Our new meta-analysis on arterial line blood cultures Contamination rate with arterial catheter–drawn cultures was comparable to venipuncture & lower vs venous catheter–drawn cultures 📌 In critically ill adults, arterial line sampling may be a reasonable alternative. doi.org/10.1093/cid/...

doi.org

Contamination of blood cultures drawn from arterial catheters versus venipuncture or venous catheters in critically ill patients: a systematic review and meta-analysis

AbstractBackground. Arterial catheter-drawn blood culture sampling may reduce patient discomfort and healthcare providers’ workload. Guidelines discourage

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giovannilandoni.bsky.social @giovannilandoni.bsky.social · 27/05/2025

wow this personalized approach by Fabio Guarracino (Pisa, Italy) is really attractive for ICU patients

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giovannilandoni.bsky.social @giovannilandoni.bsky.social · 04/04/2025

What makes a successful RCT? Any idea on what to say here in Washington tomorrow? www.kdctmeeting.com

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giovannilandoni.bsky.social @giovannilandoni.bsky.social · 21/03/2025

C-POPE or C-PAP? after Pope Francis used non invasive ventilation for days, we might start call C-PAP as C-POPE to improve dissemination among lay people and physicians who did not read our @bjajournals.bsky.social article presented in @criticalcarereviews.com pubmed.ncbi.nlm.nih.gov/39753402/

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JAMA @jama.com · 18/03/2025

The initiation of vasopressin following recommendations by a reinforcement learning model was associated with decreased mortality in patients with septic shock already receiving norepinephrine. ja.ma/3FOK2WU #ISICEM25

Figure 2. Comparison of Clinician-Observed Administration of Vasopressin With Treatment Recommended by the Reinforcement Learning Rule

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JAMA @jama.com · 18/03/2025

Among patients with moderate to severe ARDS, inhaled sedation with sevoflurane resulted in fewer ventilator-free days at day 28 and lower 90-day survival than sedation with propofol. ja.ma/4kxDZGm #ISICEM25

Visual Abstract. Inhaled Sedation in Acute Respiratory Distress Syndrome

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