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Summary - 83rd Pittsburgh Diffraction Conference. Online registration by Cvent

The workshop is a pre-conference event for the 83rd Pittsburgh Diffraction Conference, a 3-day meeting at SLAC featuring lectures and poster presentations across chemistry, physics, and structural biology. PDC info is available here: cvent.me/Eaamay

cvent.me

83rd Pittsburgh Diffraction Conference

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The workshop will intro a full in-silico drug discovery workflow, from receptor and ligand preparation through docking and interpretation. Newly developed, open-source fragment screening pipelines, being made available to SSRL structural biology users, will also be demonstrated.

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Structure Based Computational Methods in Drug Design Workshop at SSRL

Workshop news: SSRL Structural Molecular Biology group invites you to the Structure-Based Computational Methods in Drug Design Workshop, a hands-on event on September 15, 2026. Learn more and apply: smb.slac.stanford.edu/news/worksho... Space may be limited, so early application is recommended.

smb.slac.stanford.edu

The 78th Annual Pittsburgh Diffraction Conference is a three day event featuring lectures and poster presentations covering a wide range of subject matter of interest to researchers in chemistry, phys...

Please remember to cite the NIH NIGMS R24 National Resource grant in any publications if the NCC is helpful in crystallizing your sample! 💎💎💎💎💎 Crystallization at the National Crystallization Center at UB-HWI was supported through NIH grant R24GM141256. 💎💎💎💎💎

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To reserve a spot in the queue for an upcoming crystallization screening run email getacrystal at buffalo dot edu by the reservation deadline. More details: www.getacrystal.org

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Reminder! ⏰ Reservation deadline for the July 2026 HT crystallization screen at the NCC is tomorrow 7/10/26! ⏰ 📦 Acceptance & Plate Setup: 💎 Tues 7/11-Thurs 7/16 💎 Mon 7/20-Thurs 7/24 How does it work? We use 1536 different crystallization conditions in 1 microassay plate to help find 💎s!

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& please don't forget to cite the NIH NIGMS R24 National Resource grant in any publications if the NCC is helpful in crystallizing your sample! 💎💎💎💎💎 Crystallization at the National Crystallization Center at UB-HWI was supported through NIH grant R24GM141256. 💎💎💎💎💎

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When you are ready to send your sample (to arrive during the package acceptance dates) fill out the sample submission form and email tracking details for your shipment. We monitor 💎 growth with state-of-the-art imaging techniques, empowering rapid the detection of macromolecular crystals!

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We use microbatch-under-oil to efficiently sample a broad chemical parameter space. More details: www.getacrystal.org To reserve a spot in the queue for an upcoming crystallization screening run email getacrystal at buffalo dot edu by the reservation deadline

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⏰ Reservation deadline for the June 2026 HT crystallization screen at the NCC is today Friday 6/5/2026! ⏰ 📦 Acceptance & Plate Setup: 💎 Tues 6/9-Thurs 6/11 💎 Mon 6/15-Thurs 6/18 How does it work? We use 1536 non-redundant crystallization conditions in one microassay plate! 💎💎💎💎💎

The bumbling biochemist (Bri Bibel) @bumblingbiochemist.bsky.social · 21/05/2026

Reposted by getacrystal

1 week to go until the next photos. . . Huge thanks to @getacrystal.bsky.social for providing affordable screening to expand crystallography access to PUIs! My students are learning so much and it's so great showing them a bit of my past life!

The bumbling biochemist (Bri Bibel) @bumblingbiochemist.bsky.social · 22/05/2026

Reposted by getacrystal

Huge thanks to the NCC @getacrystal.bsky.social for providing affordable screening to expand crystallography access to PUIs (Primarily Undergraduate Institutions)! My students are learning so much and it's so great showing them a bit of my past life! youtu.be/F5HtZ2-3d8c

youtu.be

X-ray crystallography overview

YouTube video by the bumbling biochemist

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getacrystal @getacrystal.bsky.social · 01/06/2026

So wonderful to see all of your great crystal hits using the HT screen at the National Crystallization Center @getacrystal.bsky.social! And we love all of your material on 💎!! #structuralbiology #crystallography #crystallization #scicomm

The bumbling biochemist (Bri Bibel) @bumblingbiochemist.bsky.social · 30/05/2026

Reposted by getacrystal

One of the most exciting things in my lab recently has been introducing my students to x-ray crystallography (thanks @getacrystal.bsky.social!), which I haven't dabbled in since grad school! Today's lesson: getting crystals! youtu.be/9h8NoMnZUrc

youtu.be

Getting crystals! An overview of macromolecular (e.g., protein) crystallization methods

YouTube video by the bumbling biochemist

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The team in the National Crystallization Center is amazing: @xtalmaker.bsky.social, @gabbygrowsxtals.bsky.social al, Tiffany Wright, Elizabeth Snell, @mirandalynchphd.bsky.social & Stephen Potter. Crystallography is just 💯 fun! 💎💎💎💎💎

Very grateful to the Workshop Sponsors: NIGMS R24GM14125 National Resource funding, @SPTLabtech, @mitegen.com, HAMPTON RESEARCH, Hudson Lab Automation, Inc., SWISSCI, FORMULATRIX, & American Union of Crystallography - THANK YOU for your support!

Sponsors for the Applied Crystallization Workshop

Thank you to the participants for an engaging and fun workshop! It was wonderful to have instructors Crissy L. Tarver & Aina Cohen from Stanford Synchrotron Radiation Lightsource at SLAC National Accelerator Laboratory join us in Buffalo for the workshop!

Scientist showing how to harvest crystals with correct PPE

Candid snapshots from the Game Night after day one and during the workshop

Last week, @getacrystal.bsky.social hosted the April 2026 Applied Crystallization Center Workshop at @ubuffalo.bsky.social! Participants learned about construct design, HT crystallization 💎 screening, optimizing 💎 hits, using robotic 🤖 dropsetters and cocktail 🍸 makers, & fishing crystals 🎣 💎!

Group photo of participants and instructors from the Applied Crystallization Workshop

Scientist describing the importance of construct design in crystallization

Scientist describing the phase diagram in crystallization

Participants learning how to set up robotic dropsetters

getacrystal @getacrystal.bsky.social · 05/03/2026

MARCH into protein crystallization screening this month at the NCC 🌷🌧️💎 Reservation Deadline: Fri Mar 6th Package Acceptance & Plate Setup: Tues Mar 10th – Thurs Mar 12th Mon Mar 16th – Thurs Mar 19th e: getacrystal@buffalo.edu

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getacrystal @getacrystal.bsky.social · 15/01/2026

New in 2026: We are partnering with data collection and processing workshops so you can collect X-ray diffraction data on the crystals you grow! RapiData at SSRL at SLAC National Accelerator Laboratory Data Collection and Processing Bootcamp at NE-CAT at APS at Argonne National Laboratory

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getacrystal @getacrystal.bsky.social · 15/01/2026

You can bring your sample to work with! 🧪 💎 🔬 * Workshop #1: April 23rd & 24th (app deadline 2/23) * Workshop #2: June 2nd & 3rd (app deadline 4/27) Apply: forms.gle/LLFaPErHpe3Q... (spaces limited) * Limited travel support is available for US-based researchers *

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getacrystal @getacrystal.bsky.social · 15/01/2026

We are excited to announce the 💎 2026 Applied Crystallization Workshop 💎 at @getacrystal.bsky.social at University at Buffalo! Dive into Biomolecular Crystallization! We are holding 2 workshops in 2026. Each will be an intensive, hands-on session to learn about crystallizing your ❤️ biomolecule!

Flyer for the 2026 Applied Crystallization Workshop at the National Crystallization Center at University at Buffalo.
What? A 2 day macromolecular crystallization workshop designed
to immerse you in crystal growth methods to jumpstart your structural
biology efforts.
Who? Open to trainees of all levels and early career researchers
Where? On-site at our state-of-the-art crystallization facility in Buffalo, NY
Favored applicants will have previously submitted samples to the NCC for crystallization screening and will have a protein sample to bring on-site for workshops.

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getacrystal @getacrystal.bsky.social · 07/01/2026

Is your New Year's resolution to unveil structural details for your biological macromolecule? Reserve a spot in our January protein crystallization run before Friday! Package Acceptance & Plate Setup: Tues Jan 12th – Thurs Jan 15th Tues Jan 20th – Thurs Jan 22nd

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getacrystal @getacrystal.bsky.social · 31/12/2025

Interesting in receiving emails from the National Crystallization Center about screening run dates, workshops, and more? 📨💎 Sign up by sending an email with a blank subject line to crystallization-subscribe@chtsb.org, then respond to the confirmation email to add your email to the list.

getacrystal @getacrystal.bsky.social · 31/12/2025

As 2025 comes to a close, wishing a Happy New Year from the National Crystallization Center! 💎❄️💎❄️💎❄️💎❄️💎❄️ www.getacrystal.org

Happy New Year message from the National Crystallization Center. Images include microcrystals (white against a black background) and a series of four different crystallization wells with macrocrystals.

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getacrystal @getacrystal.bsky.social · 04/12/2025

Grateful to NIH National Institute of General Medical Sciences for funding and making state-of-the-art instrumentation and experiments available to our user community! 💎💎💎💎💎💎💎💎💎💎

getacrystal @getacrystal.bsky.social · 04/12/2025

🎉 So excited for the new instrumentation in the National Crystallization Center! We can't wait to set up new crystallization 💎 experiments with the new 🦟 🤖! 📷 @gabbygrowsxtals.bsky.social, Tiffany Wright & @mirandalynchphd.bsky.social - instrument in 📦. www.getacrystal.org @ubuffalo.bsky.social

Two scientists excited about new instrumentation (currently still in a crate).

A scientist in front of a crate with a new Mosquito instrument

A Mosquito instrument (what the new one will look like once it is set up).

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getacrystal @getacrystal.bsky.social · 05/11/2025

The National Crystallization Center is hiring for two positions: a research scientist position focused on progressing our crystallization optimization projects, and a research support specialist to support operations of the Crystallization Center!

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getacrystal @getacrystal.bsky.social · 29/10/2025

Email getacrystal@buffalo.edu to reserve by Nov 7th 🍂🍁 Package Acceptance & Plate Setup: Wed Nov 12th – Thurs Nov 13th Mon Nov 17th – Thurs Nov 20th

getacrystal @getacrystal.bsky.social · 29/10/2025

Get a crystal this November with our high-throughput crystallization screening service! This month, we are running both SOLUBLE and MEMBRANE crystallization screens. 🔮 Details ⬇️⬇️⬇️

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getacrystal @getacrystal.bsky.social · 03/10/2025

🚨💎💎💎💎💎💎💎💎💎💎🚨 Reservation deadline for the October 2025 high-throughput crystallization screen at the National Crystallization Center is today Friday October 3! www.getacrystal.org

getacrystal.org

National Crystallization Center | University at Buffalo Hauptman-Woodward Research Institute

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getacrystal @getacrystal.bsky.social · 24/09/2025

Not being able to crystallize your biomolecule of interest? Now that's scary. 😱 Try our high-throughput screen! October 2025 Soluble (taking reservations) Reservation Deadline: Fri Oct 3rd Package Acceptance & Plate Setup: Tues Oct 7th – Thurs Oct 9th Tues Oct 14th – Thurs Oct 16th

sarahejbowman @xtalmaker.bsky.social · 02/06/2025

Reposted by getacrystal

Just in time for Pride month! Celebrating our recent publication in @actacrystf.iucr.org by highlighting our rainbow of protein crystals! 🏳️‍🌈💎 Great to work with @gabbygrowsxtals.bsky.social & Vivian Stojanof on this paper! doi.org/10.1107/S205... #crystallization #crystals #structuralbiology

Picture of twelve wells of protein crystallization - arranged in a rainbow pattern. With scale bars.

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getacrystal @getacrystal.bsky.social · 03/06/2025

@getacrystal.bsky.social & SSRL are out in force teaching at the New Opportunities for Structural Biology Research Workshop in TN this week! Thanks Jamaine Davis for making the workshop happen & the invite! Nice work @gabbygrowsxtals.bsky.social, Tiffany, Darya & Crissy! @ubuffalo.bsky.social

Scientist presenting about protein crystal growth

Two scientists with a presentation about structural biology

Scientist presenting about structural biology

Scientists before presenting at the structural biology workshop

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getacrystal @getacrystal.bsky.social · 03/06/2025

We love helping researchers crystallize their biomolecules - crystals are so pretty! 👀🧪🔬♥️💎 Interested in the high-throughput crystallization screen at the National Crystallization Center at UB HWI in Buffalo NY? Check the website: www.getacrystal.org Next reservation deadline Fri 6/6/25!

getacrystal.org

National Crystallization Center | University at Buffalo Hauptman-Woodward Research Institute

getacrystal @getacrystal.bsky.social · 08/05/2025

Reminder: ⏰ May 2025 Crystallization Screen Deadline is TOMORROW Fri 5/9 Package Acceptance & Plate Setup: Tues 5/13 – Thurs 5/15 Mon 5/19 – Thurs 5/22 email htslab@hwi.buffalo.edu to reserve your spot! www.getacrystal.org 💎💎💎💎💎💎💎💎💎💎

getacrystal.org

National Crystallization Center | University at Buffalo Hauptman-Woodward Research Institute

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getacrystal @getacrystal.bsky.social · 21/03/2025

Nice job with the #crystallization workshop in PR, Gabby! Love seeing so many new #structuralbiologists excited to learn about #crystallization #crystallography #structure.

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getacrystal @getacrystal.bsky.social · 21/03/2025

Want showers of #crystals this spring? Send your sample in for xtaln screening with us in April! April 2025 Soluble Reservation Deadline: Fri Apr 4th Package Acceptance & Plate Setup: Tues Apr 8th – Thurs Apr 10th Mon Apr 14th – Thurs Apr 17th email htslab@hwi.buffalo.edu for reservations

getacrystal @getacrystal.bsky.social · 25/02/2025

March 2025 Soluble (taking reservations) Reservation Deadline: Fri Mar 7th Package Acceptance & Plate Setup: Tues Mar 11th – Thurs Mar 13th Mon Mar 17th – Thurs Mar 20th email htslab@hwi.buffalo.edu to reserve your spot!

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getacrystal @getacrystal.bsky.social · 31/01/2025

please include: your name/PI name Insitution Number of samples requested Estimated shipping date

getacrystal @getacrystal.bsky.social · 31/01/2025

We are happy to announce the upcoming runs for crystallization in February! Email us at htslab@hwi.buffalo.edu to reserve. February 2025 Soluble Reservation Deadline: Fri Feb 7th Package Acceptance & Plate Setup: Tues Feb 11th – Thurs Feb 13th Mon Feb 17th – Thurs Feb 20th

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getacrystal @getacrystal.bsky.social · 20/12/2024

Thank you for crystallizing with the National Crystallization Center and we look forward to crystallizing with you in the New Year! Happy holidays! ❄️💎❄️💎❄️💎❄️💎❄️💎❄️💎

getacrystal @getacrystal.bsky.social · 20/12/2024

You and your work contribute greatly to our successes and reasons to be here. Without you there would be no us. Thank you for your hard work and great contributions to science. Wishing you all a joyful holiday season.