Jha et al. show that the transmembrane protein CD44 restricts EGFR mobility to maintain an EGFR–PI3K–Rac gradient during bleb-based cell migration.

This study by Brancheriau et al. reveals a mechanism that cells use to sense chromosome position to properly divide. This pathway may be more dominant in cells with higher ploidy, such as cancer cells...

Bleb-based cell migration involves rapid plasma membrane expansion driven by intracellular pressure. How the membrane reorganizes its curvature and...