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GaneshaPitchai

@ganeshapp.bsky.social
128 followers 374 following 1 posts

Dad, Biochemist @GenomicsUnitAlumni @OxfordAlumni #Biophysics #DNA Repair and Replication #Ubiquitin #BLM #CryoEM #Equalityinscience All views are my own

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GaneshaPitchai @ganeshapp.bsky.social · 29/06/2026
Excellent meeting at #ESHG2026 Gothenburg. The gap between detection and interpretation remains one of the biggest challenges. The convergence of genetics and cell biology is producing answers that directly impact patients. 🧬 #ESHG2026 #FunctionalGenomics #VariantClassification #RareDiseases
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Reposted by GaneshaPitchai
Francesca Ciccarelli @ciccarellilab.bsky.social · 03/01/2025
Best start of 2025: our study on the dual role of CDKN2A in cancer evolution (rdcu.be/d5pty) is out in @naturecancer.bsky.social! Big thanks to Piyali Ganguli who led it, all coauthors and @cancerresearchuk.org archuk.org @crick.ac.uk @qmbci.bsky.social bci.bsky.social for support! Summary below
rdcu.be
Context-dependent effects of CDKN2A and other 9p21 gene losses during the evolution of esophageal cancer
Nature Cancer - Ganguli et al. show that CDKN2A loss in Barrett’s esophagus prevents esophageal adenocarcinoma initiation by counterselecting subsequent TP53 loss and report context-dependent...
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Reposted by GaneshaPitchai
Bartomeu Colom @bartomeucolom.bsky.social · 29/11/2024
'Characterizing the evolutionary dynamics of cancer proliferation in single-cell clones with SPRINTER' www.nature.com/articles/s41...
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