Will Fuller @fuller-lab.bsky.social · 06/07/2026How do phosphorylation and palmitoylation talk to each other? 🤔 Our new preprint identifies #phosphorylation of Kv4.3 as a priming event that promotes channel #palmitoylation and shapes channel activity. A fascinating example of PTM cross-talk in the heart. ❤️⚡ doi.org/10.64898/202...doi.orgA phosphorylation‑dependent mechanism controls splice variant-specific S‑palmitoylation of cardiac Kv4.3S-palmitoylation modulates the activity of many cardiac ion channels, yet the upstream signals that control this post-translational modification (PTM) are poorly defined. Here we identify a phosphoryl... 061
Will Fuller @fuller-lab.bsky.social · 06/07/2026It’s graduation day in the Fuller Lab! I look ridiculous but these two hard working PhDs absolutely deserve to celebrate! 080
Will Fuller @fuller-lab.bsky.social · 02/10/2025Delighted to invite applications for a PhD project in the group. Come and do some awesome biochemistry and physiology in a truly interdisciplinary team! www.findaphd.com/phds/project...findaphd.comPhD Studentship in Molecular Physiology – Protein-Protein Interactions and Therapeutic Targeting of Cardiac Ion Channels at University of Glasgow on FindAPhD.comPhD Project - PhD Studentship in Molecular Physiology – Protein-Protein Interactions and Therapeutic Targeting of Cardiac Ion Channels at University of Glasgow, listed on FindAPhD.com 031
Will Fuller @fuller-lab.bsky.social · 16/05/2025Well here’s an exciting opportunity! Who wants to spend 5 years working on S-acylation as part of a fantastic multidisciplinary team? #acylation #cellbiology #glasgow www.jobs.ac.uk/job/DNB111/r...jobs.ac.ukResearch Assistant/Associate at University of GlasgowApply for the Research Assistant/Associate role on jobs.ac.uk, the top job board for academic positions in higher education. View details and apply now. 0103
Reposted by Will FullerUofG School of Cardiovascular and Metabolic Health @uofgscmh.bsky.social · 28/02/2025This month is Heart Month! Professor Will Fuller explains what his research is about. Will Fuller’s research group works on cellular and molecular mechanisms that control normal physiology in the heart, and how these things stop working properly to cause disease. (1/4) 182
Reposted by Will FullerJon Cooper @joncooper-us.bsky.social · 28/02/2025Pass it on. #StandWithUkraine 11718003234119
Will Fuller @fuller-lab.bsky.social · 07/02/2025Soooo excited to share this, just published. www.nature.com/articles/s41.... It started as a crazy ‘Friday afternoon’ experiment and just… worked. And kept on working. We fused a #nanobody to a #thioesterase. This delivers the thioesterase to a target and specifically depalmitoylates this proteinnature.comNanobody-thioesterase chimeras to specifically target protein palmitoylation - Nature CommunicationsReversible palmitoylation regulates the activity and localisation of numerous proteins. Here, Kuo et al develop nanobody-based reagents to specifically target palmitoylation of individual proteins, us... 2225
Will Fuller @fuller-lab.bsky.social · 03/02/2025Why have you changed dozens of instances of ‘alpha1C’ in our manuscript to ‘alpha1 C’? It isn’t a unit. It was right the first time. 000
Will Fuller @fuller-lab.bsky.social · 11/01/2025Frozen hair, frozen eyebrows, frozen everything on Beinn Udlamain and Sgàirneach Mhòr today! First hill of the year. Great to be out! 060
Will Fuller @fuller-lab.bsky.social · 04/01/2025A day making music in a beautiful location. Saint Seans and Strauss and an appreciative audience! 050
Will Fuller @fuller-lab.bsky.social · 19/12/2024Two papers accepted in one week caps a remarkable year of success. There have been difficult and fallow years in my career. This has not been one of them and I will celebrate that! Cheers! 🎉☃️🎄 0130
Will Fuller @fuller-lab.bsky.social · 12/12/2024www.ukri.org/news/bbsrc-i... Well, this is very exciting. A welcome boost to S-acylation research in the UK. Very much looking forward to working as part of a fantastic teamukri.orgBBSRC injects £20 million into long-term discovery researchBBSRC is backing four major research projects to help pioneer critical advances in healthy ageing, drug discovery and sustainable agriculture. 491
Will Fuller @fuller-lab.bsky.social · 12/12/2024Give us your acclaim. Or don’t. It won’t really matter either way. They used to pretend there was a vote. Now they don’t even bother with that #fifa #corrupt www.theguardian.com/football/202...theguardian.comA vote without a vote: the Saudi World Cup is an act of violence and disdain | Barney RonayThe shamelessness of Fifa’s process was fully on show in Zurich during a display of contempt for governance, democracy, love, hope and good sense 040
Will Fuller @fuller-lab.bsky.social · 11/12/2024Community sense check required… Reviewer asked us to show using proteomics that our new reagent doesn’t have off target effects. In a whole cell proteome, expression of one protein (our reagent) has changed. Reviewer: now you need to look at proliferation and viability assays. Feels unreasonable? 010
Will Fuller @fuller-lab.bsky.social · 09/12/2024Exciting opportunity for a really cool PhD project! www.gla.ac.uk/postgraduate...gla.ac.ukUniversity of Glasgow - Postgraduate study - Centres for Doctoral Training - NorthWest Biosciences - Our Projects - Underpinning Bioscience - A CHEMICAL BIOLOGY APPROACH TO IDENTIFY NOVEL SUBSTRATES... 064
Will Fuller @fuller-lab.bsky.social · 29/11/2024I love teaching in this space. Millions of times better than the lecture theatres I endured during undergrad days. Now I just have to hope the students turn up ready to hear about #lipidrafts 140
Reposted by Will FullerUofGNews @uofgnews.bsky.social · 27/11/2024Our first post on Bluesky - the beautiful Cloisters and their twinkling string winter lighting @uofglasgow.bsky.social Follow us to read about the amazing research stories and projects being undertaken across our campuses. 211322
Will Fuller @fuller-lab.bsky.social · 24/11/2024One week on here and am already connected to a much bigger network than I managed in the other place. And no bots! #betterplace 040
Reposted by Will FullerThomas Arnesen @natmachinery.bsky.social · 21/11/2024go.bsky.app/HqEcaCw 144121
Reposted by Will FullerRichard Barrett-Jolley @richardbj.bsky.social · 19/11/2024May be a bit premature, but here is the Starter Pack I am trying to populate for #IonChannel research. Ping me and I’ll add you obviously! (Or to be removed) go.bsky.app/6taxHfx @jgenphysiol.bsky.social @auditorynerves.bsky.social @plesslab.bsky.social @rainbowlabuol.bsky.social 203015
Will Fuller @fuller-lab.bsky.social · 19/11/2024Ah, the annual magic of lab Christmas. This year they wrapped my office with me still inside it. 1111
Will Fuller @fuller-lab.bsky.social · 19/11/2024The annual Christmas decorating of the lab has started. There are lights everywhere. I’m in my office and all I hear is the sound of decorations being fixed to my door. #sendhelp 280
Will Fuller @fuller-lab.bsky.social · 18/11/2024Paper is ready to resubmit 9 months to the day since I first clicked ‘submit’. This has been quite a labour of love that I will be excited to share (soon, please!) 060
Will Fuller @fuller-lab.bsky.social · 17/11/2024www.theguardian.com/technology/2... Interesting take in here… do all social media algorithms inevitably mean those that shout loudest end up getting the most attention? Will every platform eventually just collapse in on itself like X?theguardian.comIs this (finally) the end for X? Delicate Musk-Trump relationship and growing rivals spell trouble for platformThe former Twitter could fade away, or help shape a dark future hosting voices of a new authoritarian world 040
Will Fuller @fuller-lab.bsky.social · 16/11/2024Well, this is exciting. A 5 year postdoc position in my lab. Do ion channels appeal to you? What about calcium? This is going to be such a fun project!👇 my.corehr.com/pls/uogrecru...my.corehr.com' 0125
Reposted by Will FullerUte Hellmich @hellmichgroup.bsky.social · 16/11/2024Ok, trying to bring my community back together... I created a starter pack for lipids and membrane protein aficionados! Feel free to share, add and distribute, so we can come together again! 😍 go.bsky.app/AEeXh86 7112565