iiinova — where your digital self keeps evolving

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@LaBonneLaB @labonnelab.bsky.social · 08/07/2025

This is so wrong-headed. You could not pay me to take a drug that was not tested in animals, and animal models remain absolutely essential for discovery research www.statnews.com/2025/05/19/a...

statnews.com

There is no replacement (yet) for animal models in medical research

The NIH is “reducing animal use in research.” But there is no replacement for animal models.

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Amy Sater @amysater.bsky.social · 08/07/2025

What Carole said -

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@LaBonneLaB @labonnelab.bsky.social · 09/07/2025

It is absolutely crazy to think we no longer need model organism research. www.sciencedirect.com/science/arti...

sciencedirect.com

There is no replacement for animal models in medical research

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Xenbase @xenbase.bsky.social · 10/07/2025

It is absolutely crazy to think we no longer need model organism research. - Carole Labonne www.sciencedirect.com/science/arti... #science #devbio #xenopus #frogs

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Frog Wranglers @frogwranglers.bsky.social · 11/07/2025

This is mission CRITICAL. Please comment.

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Xenbase @xenbase.bsky.social · 14/05/2025

Congratulations to Ray Keller, PhD for his election to the National Academy of Sciences. www.xenbase.org/xenbase/doNe... #science #devbio #xenops #frogs

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Xenbase @xenbase.bsky.social · 14/05/2025

Dr. Dominique Alfandari seeks requests for producing Xenopus antibodies. Fill out the form in the link to make your suggestions. www.xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs

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Xenbase @xenbase.bsky.social · 14/05/2025

The International Xenopus Board (IXB) Young Investigator Award recognizes an outstanding junior faculty member from any country making significant scientific achievements using Xenopus. Nominations due June 20, 2025. www.xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs

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Sarah Bowden @sarahbowden.bsky.social · 20/05/2025

Thank you for the opportunity to speak about our work amongst so many cool talks! 🐸✨

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Caroline Beck @frogsquisher.bsky.social · 22/05/2025

Excited for day one of the first @ epilepsyinst.bsky.social conference! If you ever wanted to know how tadpoles can help us understand DEE please come and chat at poster 2

epilepsyinst.bsky.social

Epilepsy Research Institute (@epilepsyinst.bsky.social)

Radically advancing epilepsy research.

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John Wallingford @jbwallingford.bsky.social · 23/04/2025

So incredibly happy that Ray Keller was elected to the AAAS! He's a pioneer of the cell biology of morphogenesis and of embryo mechanics, and a hero of mine. So grateful for his outstanding work. Even more grateful that he always took me seriously congrats Ray!!! www.amacad.org/new-members-...

Frog Wranglers @frogwranglers.bsky.social · 14/04/2025

Cool new work on metabolic activity in embryonic cell migration using #xenopus! journals.biologists.com/jcs/article/...

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Frog Wranglers @frogwranglers.bsky.social · 14/04/2025

#xenopus and chickens coming together to parse Six1 targets and deafness risk genes! journals.biologists.com/dev/article/...

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John Wallingford @jbwallingford.bsky.social · 07/04/2025

“We want to do something more interactive,” my graduate cell biology students said. “Like what?” I replied.

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Frog Wranglers @frogwranglers.bsky.social · 08/04/2025

Cool new #xenopus paper on the contribution of sperm epigenetic marks on development! www.nature.com/articles/s41...

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Anh Hoang Le, PhD 🏳️‍🌈🏴󠁧󠁢󠁳󠁣󠁴󠁿🇻🇳 @anhhle2702.bsky.social · 31/03/2025

Does anyone know why Ensembl no longer have genome sequence of Xenopus laevis anymore??? Or am I missing something? Has this always been the case? @ensembl.bsky.social

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Frog Wranglers @frogwranglers.bsky.social · 02/04/2025

Check it out! #xenopus to the rescue for functional genetics! 🧬 🐸

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Frog Wranglers @frogwranglers.bsky.social · 11/03/2025

Think you’re stressed? Check out this new work on inducing tissue strain coupled to live imaging 🐸✨ pubmed.ncbi.nlm.nih.gov/40059484/

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John Wallingford @jbwallingford.bsky.social · 21/02/2025

Preprint Alert! Juyeon Hong in the lab has dissected the molecular organization of distal tips of vertebrate motile cilia. She even found a new compartment in the extreme distal tip marked by Ccdc78 and Ccdc33. Give it a read! @biorxiv-cellbio.bsky.social www.biorxiv.org/content/10.1...

biorxiv.org

Molecular organization of the distal tip of vertebrate motile cilia

The beating of cilia on multi-ciliated cells (MCCs) is essential for normal development and homeostasis in animals. Unlike basal bodies or axonemes, the distal tips of MCC cilia remain poorly defined....

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Jakub Harnos lab @harnoslab.bsky.social · 12/02/2025

Our Xenopus team in action! 🐸🐸P.S.: they shared this photo with their PI voluntarily 👍👏🥹

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Frog Wranglers @frogwranglers.bsky.social · 10/02/2025

Give yourself the highest Valentine of all and apply to the Xenopus CSHL course! Applications due Feb 14! ❤️🐸❤️

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John Wallingford @jbwallingford.bsky.social · 03/02/2025

Birth defects are diseases of development and are the #1 cause of death in the first year of life. And birth defects kill more than twice as many children as cancer. 4% of ALL hospitalizations (for all ages) are due to birth defects. Economic impact of birth defects is > 22 billion dollars per year.

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Dr. Brittany J. Carr @drbjcarr.bsky.social · 04/02/2025

A happy lab update. We have healthy froglets! 🐸💚 We switched everything to RO, and that fixed it. Not sure exactly what's going on, but we think that somewhere, someone is accidentally backwashing acid into the demineralized water system. More investigation is required. 🐸 🧪

An image of three very small, newly morphed froglets. Two are facing the camera, and one is further back and facing away from the camera.

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Dr. Peter Walentek (Walentek Lab) @walenteklab.bsky.social · 05/02/2025

We have extended the deadline until Feb. 14th. Take the opportunity, funding support is avaliable! 🐸⚠️ meetings.cshl.edu/courses.aspx...

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Frog Wranglers @frogwranglers.bsky.social · 04/02/2025

Cool new #xenopus 🐸 ✨preprint✨ on klf family genes and neural crest development! Check it out! @labonnelab.bsky.social pubmed.ncbi.nlm.nih.gov/39868152/

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John Wallingford @jbwallingford.bsky.social · 03/02/2025

Anyone tried/trying expansion microscopy on Xenopus? Would LOVE to talk shop. @frogwranglers.bsky.social @xenbase.bsky.social #xenopus

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Labfrog @youngfroglab.bsky.social · 29/01/2025

Love this video!

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Frog Wranglers @frogwranglers.bsky.social · 24/01/2025

Happy #xenopus #fluorescencefriday from this timelapse of beads transiting a tadpole gut- in honor of @pieceofkate.bsky.social graduating! 🐸💩

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Frog Wranglers @frogwranglers.bsky.social · 21/01/2025

Cool new #Xenopus work on stretch, cell migration, and electrical fields in vivo! www.nature.com/articles/s41...

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Frog Wranglers @frogwranglers.bsky.social · 15/01/2025

Everyone's favorite sight in the lab. IYKYK #Xenopus

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Frog Wranglers @frogwranglers.bsky.social · 14/01/2025

Cool new paper on the relationship between microtubule dynamics and temperature taking advantage of different #xenopus frog species that live at different temperatures! Check it out! www.sciencedirect.com/science/arti...

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Frog Wranglers @frogwranglers.bsky.social · 07/01/2025

Cool new ✨preprint✨ on temperature scaling in early embryonic cell divisions using #xenopus! www.biorxiv.org/content/10.1...

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Frog Wranglers @frogwranglers.bsky.social · 06/01/2025

Check out this cool new preprint on limb regeneration and oxygen sensing using #xenopus! @canaztekin.bsky.social www.biorxiv.org/content/10.1...

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Frog Wranglers @frogwranglers.bsky.social · 06/01/2025

Cool new paper on proton sensing using #xenopus! www.sciencedirect.com/science/arti...

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Jacques Robert @jackofrogy.bsky.social · 22/12/2024

A special present from my lab during our jumping frog lab holiday party.

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Matyas Bubna-Litic @matyasbl.bsky.social · 20/12/2024

Last #FluorescenceFriday of the year! (at least from me) This fluorescent in situ probe worked much better than I expected. Chordin expression seen here at early gastrula stage of a #xenopus embryo.

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Xenbase @xenbase.bsky.social · 17/12/2024

Jaeger et al. screened Adeno-associated viral tools (AAVs) in three different amphibian species brains identifying serotypes that transduce neurons. Published in Developmental Cell. www.xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs

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