iiinova — where your digital self keeps evolving

Frank I. Scott, MD MSCE @frankiscottmd.bsky.social · 10h

very different model than the one Lactated Ringers Middle School is deploying.

Frank I. Scott, MD MSCE @frankiscottmd.bsky.social · 01/10/2026

Excited to see this manuscript that I collaborated on with my colleague Siobhan Proksell in press! The Data Deluge: Balancing Information Overload and Evidence-Based Medicine in Gastroenterology Fellowship - Clinical Gastroenterology and Hepatology www.cghjournal.org/article/S154...

cghjournal.org

The Data Deluge: Balancing Information Overload and Evidence-Based Medicine in Gastroenterology Fellowship

The cognitive demands of gastroenterology training include countless hours studying in medical school, followed by 6 or more years of intensive on-the-job training as residents and during fellowship. ...

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Frank I. Scott, MD MSCE @frankiscottmd.bsky.social · 22/07/2026

Excited to be speaking in Seattle in August for AIBD Regionals: Join us August 15 and 16, 2026! #AIBDRegionals Register here: hmplink.ai/XkqP2n

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Frank I. Scott, MD MSCE @frankiscottmd.bsky.social · 12/06/2026

Excited to be part of Advances in IBD regionals this weekend in Nashville, hope to see you there! www.hmpglobalevents.com/aibdregional...

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Frank I. Scott, MD MSCE @frankiscottmd.bsky.social · 05/06/2026

Who knew you could take the R7 to a bears game?

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Frank I. Scott, MD MSCE @frankiscottmd.bsky.social · 30/04/2026

WWWOOOOOOOOOOOOOOOOOOOOOOO FLYERS IN OT!!

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Reposted by Frank I. Scott, MD MSCE

CU Division of Gastroenterology and Hepatology @cugastrohep.bsky.social · 28/04/2026

Our faculty & fellows have an incredible showing at #DDW2026! 125+ presentations, including 8 symposiums, 24 abstract lectures & 17 invited talks, 70+ posters. Full CU lineup medschool.cuanschutz.edu/docs/librari... @swatipatelmd.bsky.social @bilalmohammadmd.bsky.social @frankiscottmd.bsky.social

The CU Anschutz Division of Gastroenterology and Hepatology has more than 125 presentations at Digestive Disease Week spanning across all aspects of GI and Hepatology. This is a testament to our dedication and commitment to advancing science!

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Frank I. Scott, MD MSCE @frankiscottmd.bsky.social · 21/04/2026

that cross-check/boarding absolutely should have come with a game susp.

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Reposted by Frank I. Scott, MD MSCE

Duke GI @dukegi.bsky.social · 07/04/2026

🎙️Tomorrow, Duke GI Grand Rounds welcomes guest speaker @frankiscottmd.bsky.social , @cugastrohep.bsky.social, presenting “Optimizing Advanced Therapy Initiation and Disease Activity Monitoring in IBD.” 🎉We're beyond excited for this one and to host Dr. Scott live & in person! Join us at 8AM! #IBD

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Frank I. Scott, MD MSCE @frankiscottmd.bsky.social · 28/02/2026

Flyers just need to shoot from the blue line or farther and should eventually work out

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Reposted by Frank I. Scott, MD MSCE

Chris Vannini @chrisvannini.com · 19/02/2026

That pass, that move, that finish, UNBELIEVABLE

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Frank I. Scott, MD MSCE @frankiscottmd.bsky.social · 14/02/2026

US looks kind of flat since that goal.

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Frank I. Scott, MD MSCE @frankiscottmd.bsky.social · 08/02/2026

Im at an ice protest….. I’m at the health club store.

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Reposted by Frank I. Scott, MD MSCE

Carl T. Bergstrom @carlbergstrom.com · 27/01/2026

So initial experiments with Open AI's vibe-coding science tool Prism are going about as well as expected.

Rubbish paper "Is Pee Stored in the Balls" with broken diagram, broken, table, and bullshit text.

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Frank I. Scott, MD MSCE @frankiscottmd.bsky.social · 24/01/2026

Incredible framing here. Superb mastery of the English language. If only we had a word for when someone makes statements in opposition of clear fact

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Reposted by Frank I. Scott, MD MSCE

Dimitri Drekonja, MD, MS @dimitridrekonja.bsky.social · 24/01/2026

Alex Pretti was a colleague at the VA. We hired him to recruit for our trial. He became an ICU nurse- I lover working with him. He was a good kind person who lived to help and these fuckers executed him. White. Hot. Rage.

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Frank I. Scott, MD MSCE @frankiscottmd.bsky.social · 10/01/2026

Starting my 48th trip around the sun with a little bit of 4am grant app review ;)

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Frank I. Scott, MD MSCE @frankiscottmd.bsky.social · 07/01/2026

Surprised I had to scroll so far to find this. Pitch perfect ending to a show that resonated with me deeply

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CU Division of Gastroenterology and Hepatology @cugastrohep.bsky.social · 03/12/2025

Thrilled to congratulate our incoming First-Year Fellows to the @cuanschutz.bsky.social Division of GI & Hep! 🎉We welcome this incredible lineup to @cugastrohep.bsky.social & can’t wait to work w/ these future leaders! #FutureofGI #Match2026 💪 @bilalmohammadmd.bsky.social @jchristiemd.bsky.social

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Reposted by Frank I. Scott, MD MSCE

American Gastroenterological Association (AGA) @amergastroassn.bsky.social · 20/11/2025

Our new clinical practice guideline, published in AGA-Gastro.bsky.social, offers 16 evidence-based recommendations for treating moderate-to-severe #Crohnsdisease. Read more here: gastro.org/news/new-aga... @frankiscottmd.bsky.social #GISky

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Frank I. Scott, MD MSCE @frankiscottmd.bsky.social · 20/11/2025

Last, what are living guidelines? 🧑🍼 🔹With how quickly drug-development 💊 and treatment strategies ♟️ change, AGA will review new lit. 📄 and update recommendations as needed every 6 months 📝. Stay tuned for updates in the future! 10/10

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Frank I. Scott, MD MSCE @frankiscottmd.bsky.social · 20/11/2025

✳️15. For patients w/ mod-severe disease: 👍 Early advanced therapy ❌ No step-up 🪜 therapy ✳️16.🤷♂️Knowledge gap re: treating to a target of mucosal healing vs clinical remission. More data needed!

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Frank I. Scott, MD MSCE @frankiscottmd.bsky.social · 20/11/2025

✳️13, ✳️14 For TNF + IMM therapy, should you stop? 👍 Consider stopping IMM if in steroid-free remission >6mo ❌ Don’t stop TNF Should involve shared decision making, consideration of disease severity + history, comorbidities, and risk of immunogenicity 8/10

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Frank I. Scott, MD MSCE @frankiscottmd.bsky.social · 20/11/2025

✳️9, ✳️10, ✳️11, ✳️12 Combo therapy 💊+💊 🔹 IFX + thiopurine > IFX or thiopurine alone, particularly if no prior thiopurine use. 🤷♂️Knowledge gaps: Combo therapy with MTX, ADA+ IMM, or non-TNF biologics + IMM 7/10

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Frank I. Scott, MD MSCE @frankiscottmd.bsky.social · 20/11/2025

✳️5, ✳️6, ✳️7.✳️ 8 Immunomodulators 💊 ❌ Thiopurines for induction 👍 Okay to use thiopurines for maintenance 👍Methotrexate SQ for induction or maintenance ❌Methotrexate PO for induction or maintenance 6/10

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Frank I. Scott, MD MSCE @frankiscottmd.bsky.social · 20/11/2025

❗️Important❗️ 🔑High🪣or med🪣 > lower🪣 🔑 You need to factor in the patient when making tx choices, not just focus on which efficacy bucket each medication is in. Consider age 👨🦳, pregnancy status 🤰, comorbidities 🤒, functional status 👩🦽, prior med exposures, & patient preferences. 5/10

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Frank I. Scott, MD MSCE @frankiscottmd.bsky.social · 20/11/2025

What about comparative efficacy for bio-naïve & bio-exposed? ✳️3. Bio naive: Higher 🪣> Lower 🪣 Higher🪣: IFX, ADA, VDZ, UST, RIS, MIR, GUS Lower🪣: CTP, UPA ✳️4. Exposed: Higher 🪣 or Med 🪣 > Lower 🪣 Higher🪣: ADA, RIS, GUS, UPA Med🪣: UST, MIR Lower🪣: VDZ, CTP 4/10

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Frank I. Scott, MD MSCE @frankiscottmd.bsky.social · 20/11/2025

✳️1 & 2: What therapies are recommended compared to placebo? Strong rec: IFX, ADA, UST, RIS, GUS, MIR, UPA Conditional rec: CTP, VDZ Considerations: 1. Biosimilar = originator 2. SQ = IV 3. If severe disease, consider extended induction, dose esc, and higher maintenance doses. 3/10

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Frank I. Scott, MD MSCE @frankiscottmd.bsky.social · 20/11/2025

📍Used GRADE framework 📍Thresholds for clinically meaningful benefits across txs: >10% vs. pbo & >5% vs. other 💊 📍For those with no prior adv tx exposure, meds were stratified into higher vs lower efficacy. For adv tx-exposed, higher-, medium-, and lower-eff. buckets were used. 2/10

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Frank I. Scott, MD MSCE @frankiscottmd.bsky.social · 20/11/2025

🚨AGA New Guideline Alert🚨 @amergastroassn.bsky.social 🔗https://smplu.link/aga_CD_guidelines ▶️AGA Living Guideline: Pharmacologic Management of Moderate-to-Severe Crohn’s Disease I’ll break down its 16 recommendations down over the next 10 tweets 🧵 👇 #AGA #GI #CD #IBD #MedTwitter 1/10

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Frank I. Scott, MD MSCE @frankiscottmd.bsky.social · 03/10/2025

Appropriately so. Easily the most peripheral and unnecessary subscription I have. Garmin is my recorder, any serious analytics are happening in trainerroad or trainingpeaks. I often wonder why i still even pay for Strava, other than an easy interface for the grams.

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Frank I. Scott, MD MSCE @frankiscottmd.bsky.social · 30/09/2025

lotta potential cavities in that basket of cookies though. He's looking out for your future dental health

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Frank I. Scott, MD MSCE @frankiscottmd.bsky.social · 13/09/2025

Excited for the 7th annual IBD101 course, hosted by @amcollegegastro.bsky.social in Dallas, TX today! Fantastic educational program for first year gi fellows

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Frank I. Scott, MD MSCE @frankiscottmd.bsky.social · 31/08/2025

Apparently more so for some than others?

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CU Division of Gastroenterology and Hepatology @cugastrohep.bsky.social · 12/08/2025

Help us give a warm Colorado welcome 🌞🏔️to our newest IBD Faculty member- Dr. Siobhan Proksell! Dr. Proksell is an IBD specialist focusing on fertility & pregnancy in patients w/ IBD. Welcome to the team! @jchristiemd.bsky.social @frankiscottmd.bsky.social @benclickmd.bsky.social

Welcome new University of Colorado Division of Gastroenterology and Hepatology faculty member, Siobhan Proksell, MD! Dr. Proksell is an IBD specialist with a focus on fertility and pregnancy in patients managing IBD.

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Reposted by Frank I. Scott, MD MSCE

Atoosa Rabiee @atoosarabiee.bsky.social · 08/07/2025

A new but tested and tried mentorship method 👇🏼 Near-Peer mentorship 😊 @drjessicadavis.bsky.social Thank you for spearheading the project #liversky journals.lww.com/lt/abstract/...

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Frank I. Scott, MD MSCE @frankiscottmd.bsky.social · 28/06/2025

I think the 11th edition of the newspeak dictionary is due any day now, right?

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Reposted by Frank I. Scott, MD MSCE

CU Division of Gastroenterology and Hepatology @cugastrohep.bsky.social · 16/06/2025

#TaylorKarlMD and #ThomasEnkeMD took home the Dr. Marshall Freedman Award for outstanding academic and clinical records! Recipients are chosen based on academic achievements, clinical abilities, & leadership during their fellowship. Congrats! 🎉💪 @jchristiemd.bsky.social @frankiscottmd.bsky.social

Taylor Karl, MD and Thomas Enke, MD are presented with the Dr. Marshall Freedman award by Drs. Jennifer Christie and Frank Scott.

Taylor Karl, MD and Thomas Enke, MD are presented with the Dr. Marshall Freedman award by Dr. Frank Scott.

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Frank I. Scott, MD MSCE @frankiscottmd.bsky.social · 15/06/2025

“As many, for better or worse, currently believe in microorganisms like bacteria and viruses,a focus on the humors often gets a bad rap….”

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Peter Gleick @petergleick.bsky.social · 31/05/2025

There are 2 previous historical cases of countries destroying their science and universities, crippling them for decades: Lysenkoism in the USSR and Nazi Germany. The Trump administration will be the 3rd. It's not just budgets but research, institutions, expertise, and training the next generation.

Graphs showing 25 years of budgets for the National Institute of Health, NASA, and the NSF. In all cases, the proposed budget for next year is far, far below any year of the previous quarter century.

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