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Franck Polleux

@franckp.bsky.social

2.3K followers 2K following 89 posts

Neuroscientist and cell biologist. Investigator of the Zuckerman Mind Brain Behavior Institute (ZMBBI) in New York

Posts Replies Media

Franck Polleux @franckp.bsky.social · 05/08/2026

and finally a beautiful image of a single microglial cell in the cortex of a P30 mouse (failed attempt for a cover image at Neuron!! 😅):

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Franck Polleux @franckp.bsky.social · 05/04/2025

couldn't see the end of it 😍

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Franck Polleux @franckp.bsky.social · 07/03/2025

beautiful day to support science in NYC 💪🏻 #standupforscience

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Franck Polleux @franckp.bsky.social · 03/01/2025

Very proud of my lab members (past and present) for receiving the Blue Flame Award from @addgene.bsky.social based on some of our most requested and distributed plasmid reagents 😀: www.addgene.org/Franck_Polle... Addgene is such a great resource for the scientific community!

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Franck Polleux @franckp.bsky.social · 18/12/2024

Surprisingly, our work uncovered compartment-specific differences in the magnitude and temporal expression of synaptic plasticity between basal and oblique dendrites. 15/n

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Franck Polleux @franckp.bsky.social · 18/12/2024

Our key results (Fig. 4&5) identified a temporally asymmetric synaptic plasticity kernel resulting from bidirectional modifications of synaptic weights around the induction of a place field. 14/n

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Franck Polleux @franckp.bsky.social · 18/12/2024

(2) To measure changes in functional synaptic strength in vivo before and after PF induction, we used a red-shifted calcium indicator (jRGECO1a) to monitor spine calcium dynamics. We demonstrate, using a new GEVI (ASAP6) from Michael Z. Lin that spine Ca2+ amplitude faithfully reports EPSP (ΔW) 13/n

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Franck Polleux @franckp.bsky.social · 18/12/2024

To investigate the relationship between changes in synaptic weights (ΔW) and the emergence of PFs in individual CA1PNs, we developed and deployed three tools at single-cell resolution (Fig. 1): 11/n

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Franck Polleux @franckp.bsky.social · 18/12/2024

How can a neuron receiving 10,000-15,000 synaptic inputs each providing broad information (tuning) ultimately decide to fire in a highly selective manner i.e. becoming feature selective? 3/n

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