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Florian Plaza Oñate

@fplazaonate.bsky.social
35 followers 137 following 3 posts

R&D Bioinformatician at @INRAE MetaGenoPolis

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Reposted by Florian Plaza Oñate
Guillaume GAUTREAU @guigau.bsky.social · 12/05/2026
Last year CroCoDeEL was released, and now it is out in @natcomms.nature.com 🐊🎉 We also designed a webapp to explore CroCoDeEL results: scatterplots, networks, plates, verdicts, and clean reports. Try it out! 💻📊 Paper: www.nature.com/articles/s41... 🖥️: metagenopolis.github.io/CroCoDeEL_in...
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Reposted by Florian Plaza Oñate
Alexandre Almeida @alexmsalmeida.bsky.social · 10/09/2025
🚨 New pre-print from the lab! We performed a large-scale meta-analysis of the uncultured gut #microbiome in >10,000 metagenomes enabling us to identify a new candidate biomarker of health. www.biorxiv.org/content/10.1...
biorxiv.org
Meta-analysis of the uncultured gut microbiome across 11,115 global metagenomes reveals a new candidate biomarker of health
The human gut microbiome plays an important biological role in host health, yet over 60% of gut species remain uncultured and hence inaccessible to experimental manipulation. Here we analysed 11,115 h...
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Reposted by Florian Plaza Oñate
Eugen Pfeifer @eugenpfeifer.bsky.social · 10/02/2025
Excited🚨to share our first work on the human gut phageome doi.org/10.1101/2025... Always inspiring to work with @epcrocha.bsky.social , Erick D, Camille d'H and everyone else within this super dynamic consortium @inrae-france.bsky.social+@pasteur.fr+@inserm.fr! Many thanks for this great journey!🙌
doi.org
Third-generation cephalosporin antibiotics induce phage bursts in the human gut microbiome.
The use of antibiotics disrupts the gut microbiota, potentially leading to long-term health issues and the spread of resistance. To investigate the impact of antibiotics on phage populations, we follo...
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Reposted by Florian Plaza Oñate
Guillaume GAUTREAU @guigau.bsky.social · 20/01/2025
1/9 🚨 New preprint alert! Frustrated by strange results with your metagenomic data? Meet CroCoDeEL, an accurate, easy-to-use tool to detect and quantify cross-sample contamination—no need for negative controls or sample positions! 🔗 doi.org/10.1101/2025...
doi.org
CroCoDeEL: accurate control-free detection of cross-sample contamination in metagenomic data
Metagenomic sequencing provides profound insights into microbial communities, but it is often compromised by technical biases, including cross-sample contamination. This underexplored phenomenon arise...
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