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Saul Kato

@focolab.bsky.social
153 followers 158 following 25 posts

I study things that think. Neuroscience professor at UCSF. Foundations of Cognition Lab. Reformed tech founder. www.focolab.org. substack.com/@saulkato

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Saul Kato @focolab.bsky.social · 27/03/2026
HUGE congrats to my old Herophilus.com co-founder @seanescola.bsky.social on two fronts. The robotics company he co-founded was acquired by Amazon. apnews.com/article/amaz... He put out a paper proposing how to train large AI models so they acquire more cognitive functions arxiv.org/abs/2603.03414
apnews.com
Amazon buys Fauna Robotics, maker of the Sprout humanoid robot
Amazon has acquired Fauna Robotics, just under two months after the startup introduced a humanoid robot called Sprout designed for social spaces like homes and schools.
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Saul Kato @focolab.bsky.social · 22/12/2025
We noticed that a plate of C. elegans worms, under starvation conditions, forms stable living spatial structures, which we dub "worm webs". These webs seem to be scaffolded by an excreted substance from living or dead worms, which we dub "wormstuff". www.focolab.org/post/worm-we...
focolab.org
Worm Webs and Wormstuff
Sometimes a fresh pair of eyes in a lab notices a phenomenon that has been under the noses of researchers for a long time but ignored as a distraction. After more careful observations, replications, a...
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Saul Kato @focolab.bsky.social · 11/12/2025
Here's a nice 1-pager by Tomke Stürner in Current Bio about our recent article on short-term memory implemented by oscillator networks in the worm. www.focolab.org/post/an-arti...
focolab.org
An article about our article
Current Biology published a perspective article, "Short-term memory: How oscillatory networks preserve sensory history" which covers our recent paper about short-term memory in the worm. It's a nice p...
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Saul Kato @focolab.bsky.social · 11/12/2025
Skeuomorphism is back!
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Saul Kato @focolab.bsky.social · 02/12/2025
oh right, its the data
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Saul Kato @focolab.bsky.social · 31/07/2025
These university cash “deals” to restore federal funding are worrisome. They seem more naïve than pragmatic. Please no more.
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Saul Kato @focolab.bsky.social · 26/07/2025
Preprint posted for Kevin Zhou's awesome development in the Waller Lab of a gigapixel-scale microscope using a low-cost sensor array, along with Muneki Ikeda. www.focolab.org/post/large-s...
focolab.org
"Large-scale compressive microscopy via diffractive multiplexing across a sensor array" preprint released
Kevin Zhou, former postdoc in the collaborating lab of Laura Waller at Berkeley, and who recently started his own lab at University of Michigan, developed this way to achieve gigapixel-resolution high...
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Saul Kato @focolab.bsky.social · 14/07/2025
We built StarDist to detect cells in volumetric microscopy and jointly infer closed curved parametric surfaces for each cell. It's an example of an interpretable machine learning approach. More detail in the blog post and preprint. www.focolab.org/post/surfdis...
focolab.org
"SurfDist" pre-print posted
We developed an "interpretable machine learning" system to find and characterize blobs in volumetric images, such as microscopy images of cells, something we need to do all the time in our lab. The no...
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Saul Kato @focolab.bsky.social · 11/07/2025
Here’s a nice Nature news article on efforts to establish the tardigrade as a new model organism for neuroscience. www.focolab.org/post/nature-...
focolab.org
Nature does a news piece on our tardigrade work
This is a nice news article by Benjamin Plackett in Nature covering our science and community building work to establish tardigrades as a new model organism for neuroscience. Kudos to postdoc Ana Lyon...
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Saul Kato @focolab.bsky.social · 18/06/2025
An instant classic by Zheng and Meister ‪(@mameister4.bsky.social‬): www.cell.com/neuron/fullt... "...1⁢0^8... the ratio between peripheral information processing and the overall throughput of the brain. Numerically speaking, this may be the largest unexplained number in brain science. "
cell.com
The unbearable slowness of being: Why do we live at 10 bits/s?
Zheng and Meister write about the paradoxical slowness of human behavior. Although our senses gather data at 109 bits/s, our overall information throughput is only 10 bits/s. This stark contrast touch...
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Saul Kato @focolab.bsky.social · 06/06/2025
so glad websites are back.
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Saul Kato @focolab.bsky.social · 20/05/2025
Here's a curious result we found from modeling human problem solving as the composition of past remembered dynamical systems. www.focolab.org/post/recombi...
focolab.org
"Recombinant dynamical systems" pre-print posted
This is an idea and a small but curious result that I've been sitting on for a very long time. Finally got around to sharing it. It the simplest possible model I could come up with for experience-base...
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Saul Kato @focolab.bsky.social · 13/03/2025
Here's a nice article on our tardigrade work in the Transmitter: www.focolab.org/post/article...
focolab.org
Article in the Transmitter on our tardigrade work
Dori Grijseels wrote a great article about our work and preprint on tardigrades for neuroscience. https://www.thetransmitter.org/animal-models/how-tiny-tardigrades-could-help-tackle-systems-neuroscien...
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Reposted by Saul Kato
The Kavli Foundation @kavlifoundation.org · 03/03/2025
Congrats to the Kavli Institute for Fundamental Neuroscience at UCSF Collaborative Awardees! 🔬 @focolab.bsky.social, Christoph Kirst: AI-driven 3D tracking of object perception in C.elegans 🧠 Robert Stroud, Robert Edwards, James Holton: Mapping SVs w/ cryo-ET #KavliNeuro kavliifn.ucsf.edu/grants
kavliifn.ucsf.edu
Grants | ucsf-kavli
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Saul Kato @focolab.bsky.social · 13/02/2025
kleptokakistocracy
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Saul Kato @focolab.bsky.social · 12/02/2025
Data contamination (validation data leaking into training data) is a critical problem for the whole approach of (static) performance benchmarks to test large AI models. This issue needs to be surfaced more. This article for example, completely neglects it. www.nytimes.com/2025/01/23/t...
nytimes.com
When A.I. Passes This Test, Look Out
The creators of a new test called “Humanity’s Last Exam” argue we may soon lose the ability to create tests hard enough for A.I. models.
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Saul Kato @focolab.bsky.social · 11/02/2025
Prediction: AI will ultimately drive the renaissance of the fourth estate, the press, as we seek authoritative sources of information and trusted interpretation.
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Saul Kato @focolab.bsky.social · 23/01/2025
It has become impossible to distinguish real newspaper headlines from Onion headlines. We need a name for this era
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Saul Kato @focolab.bsky.social · 21/01/2025
Our paper on WormID is out. Moral: building a multi-lab data corpus boosts generalization and performance of ML labeling algorithms. We extended the Neurodata Without Borders format to support this. Resource at wormid.org. www.focolab.org/post/our-pap...
focolab.org
Our paper "Unifying community whole-brain imaging datasets enables robust neuron identification and reveals determinants of neuron position in C. elegans" is out.
https://www.cell.com/cell-reports-methods/fulltext/S2667-2375(24)00354-0Congrats Yutaka and the rest of the team! It has been a fantastic collaborative effort and we hope the community continues to bu...
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Saul Kato @focolab.bsky.social · 14/01/2025
For our inaugural post on bsky, we're happy to share our preprint on tardigrades as a new model organism for neuroscience. Exciting times for these little critters! www.focolab.org/post/our-pre...
focolab.org
Our preprint "The tardigrade as an emerging model organism for systems neuroscience" is up.
We have been making the case for some time that tardigrades, aka water bears, would be an amazing new model organism for certain big systems neuroscience questions. We put this into a detailed paper o...
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