Sign in

Flo Di Meo

@flo-dimeo.bsky.social
100 followers 200 following 4 posts

Computational chemist trying to understand drug membrane transporters in pharmacology as well as everything I don’t understand… Inserm Researcher - Limoges, France

PostsRepliesMedia
Flo Di Meo @flo-dimeo.bsky.social · 26/03/2025
Veronica's work about structural dynamics of ABCB4 finally out in CSBJ @insermna.bsky.social @inserm.fr #ABCtransporter #MD #membprot #compchem www.sciencedirect.com/science/arti...
sciencedirect.com
Membrane-dependent dynamics and dual translocation mechanisms of ABCB4: Insights from molecular dynamics simulations
ABCB4 is an ATP-binding cassette transporter expressed at the canalicular membrane of hepatocytes and responsible for translocating phosphatidylcholin…
041
Flo Di Meo @flo-dimeo.bsky.social · 26/03/2025
Glad to share collaboration with Ali Makky about New porphysomes for improved photodynamic therapy applications in JCI @univparissaclay.bsky.social @insermna.bsky.social @cnrs.fr @inserm.fr www.sciencedirect.com/science/arti...
sciencedirect.com
Next generation of porphysomes for improved photodynamic therapy applications
Porphysomes are a class of liposome-like nanoparticles that have demonstrated efficacy in photothermal therapy (PTT) and photodynamic therapy (PDT) ag…
000
Reposted by Flo Di Meo
ABC2025 @abcmeeting.bsky.social · 07/03/2025
We had an amazing time with the ABC family and already miss you all! Can’t wait to hear your exciting talks, have great discussions, and hit the slopes of the Alps again. #ABC2025 See you next time!🗻⛷️🚠🧬🧫🧪💙
2196
Flo Di Meo @flo-dimeo.bsky.social · 03/03/2025
Happy to share here our revised version of our study about membrane-dependent structural dynamics of ABCB4 membrane transporter. Huge work from Veronica @inserm.fr @insermna.bsky.social @unilim.bsky.social #ABCtransporter #MD doi.org/10.1101/2024...
doi.org
Membrane-Dependent Dynamics and Dual Translocation Mechanisms of ABCB4: Insights from Molecular Dynamics Simulations
ABCB4 is an ATP-binding cassette transporter expressed at the canalicular membrane of hepatocytes and responsible for translocating phosphatidylcholine into bile. Despite the recent cryo-EM structures...
000
Reposted by Flo Di Meo
Elena Papaleo @elenapapaleo.bsky.social · 28/02/2025
PhD Opportunity: AI-driven Protein Binder Design. Join a cutting-edge DTU & Novo Nordisk collaboration! Work with AI, automation & protein engineering in a closed-loop design pipeline. efzu.fa.em2.oraclecloud.com/hcmUI/Candid... #PhD #AI #ProteinDesign #Bioinformatics #MachineLearning #Biology
efzu.fa.em2.oraclecloud.com
PhD scholarship in AI Oracles for Fitness Landscape Optimization on Molecular Binders - DTU Health Tech
As part of a joint research collaboration between DTU and Novo Nordisk, we are looking for a Ph.D.-candidate to join our multidisciplinary research program focusing on the interplay between AI-based p...
041
Flo Di Meo @flo-dimeo.bsky.social · 20/01/2025
Surprisingly, it sounds possible for a computational chemist to also play with membrane transporters, cells and organ-on-chips in pharmacology! It took time but it was fun, thanks to Nicolas, Quentin and Isy @inserm @unilim.bsky.social in Scientific Reports rdcu.be/d6WJ6
nature.com
Proximal tubule-on-chip as a model for predicting cation transport and drug transporter dynamics
Scientific Reports - Proximal tubule-on-chip as a model for predicting cation transport and drug transporter dynamics
010