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Anthony Leonardi

@fitterhappieraj.bsky.social
4.5K followers 5 following 23 posts
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Anthony Leonardi @fitterhappieraj.bsky.social · 11/01/2026
Again
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Anthony Leonardi @fitterhappieraj.bsky.social · 11/01/2026
We spoke about this very topic for the article, why did you not attribute me with the point we discussed?
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Anthony Leonardi @fitterhappieraj.bsky.social · 05/11/2025
The lead researcher of the American Association of immunology saying they are seeing a reduction in T cells You seem to ignore that this statement is not made by a journalist
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Anthony Leonardi @fitterhappieraj.bsky.social · 05/11/2025
The bmj article which was written by a journalist, quotes the head of the American Association of immunology and several immunologists at UCSF and nih saying that they are seeing population wide effects on immune systems from Covid
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Anthony Leonardi @fitterhappieraj.bsky.social · 05/11/2025
Wow. comparatively, covid is a bloodbath to t cells. Unutmaz is an hiv investigator. He has since changed his views, and does not corroborate these statements any longer. You are free to ask him why, I suspect it's because we can not mitigate covid.
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Anthony Leonardi @fitterhappieraj.bsky.social · 05/11/2025
I stood in contrast to the people who publicly said T cells would cause us to reach herd immunity at a portion of population infected. I said on the contrary, they would be harmed, which is true.
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Anthony Leonardi @fitterhappieraj.bsky.social · 05/11/2025
Population-level T cell death is now published. It doesn't need to be validated with an R01 by me. Your parameters are off. Basically, you're making a strawman argument
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Anthony Leonardi @fitterhappieraj.bsky.social · 05/11/2025
Lets say I left medical school in 2020 to investigate something that had not occurred and was controversial at the time. You're naive to think that someone who did not do a postdoc yet would receive an R01 to do so It's published now in many sources. Is this publication also wrong?
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Anthony Leonardi @fitterhappieraj.bsky.social · 05/11/2025
@stephenjudkins.bsky.social dont be a coward and delete
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Anthony Leonardi @fitterhappieraj.bsky.social · 05/11/2025
That's the BMJ. You're a computer engineer. It's a medical journal and the science is clear. Many articles on T cell apoptosis.
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Anthony Leonardi @fitterhappieraj.bsky.social · 05/11/2025
www.bmj.com/content/390/... They've played out as I expected
bmj.com
Why scientists are rethinking the immune effects of SARS-CoV-2
“Immunity debt,” a theory to explain the global surge in non-covid infections since pandemic restrictions were lifted, is increasingly being challenged by emerging evidence. Nick Tsergas reports Myco...
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Anthony Leonardi @fitterhappieraj.bsky.social · 05/11/2025
The T cell death was published by me in 2020. Only now has population-level immune harm been acknowledged, now in the BMJ in 2025. Not bad for a medical student at the time. Care to update your followers? www.bmj.com/content/390/...
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Anthony Leonardi @fitterhappieraj.bsky.social · 13/04/2025
When you ask this guy who argued that people should count on this being like any other cold, he’s going to be the second to last to admit that harms the immune system. The last would be the intellectual fraud Zeynep Tufekci
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Anthony Leonardi @fitterhappieraj.bsky.social · 13/04/2025
The recent study that was published in the Lancet shows an increase in risk for other infections and for hospitalization by those other infections after Covid.
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Anthony Leonardi @fitterhappieraj.bsky.social · 13/04/2025
Finally, asking for infection controls is code for asking for studies in which people were intentionally infected rather than matched because he’s trying to claim there is confounding.
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Anthony Leonardi @fitterhappieraj.bsky.social · 13/04/2025
People are still even arguing over the mechanism of HIV’s harm to CD4 T cells but because they actually don’t know and it’s not 100% certain that it’s simply from dividing in the T cell. It could also be from chronically activating it with a superantigen.
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Anthony Leonardi @fitterhappieraj.bsky.social · 13/04/2025
He’s also asking for the mechanism, which is not necessary to prove that Covid actually has the effect. Many people research the mechanism behind gravity, we don’t need to prove how it works in order to prove gravity exists.
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Anthony Leonardi @fitterhappieraj.bsky.social · 13/04/2025
He can claim that those people had exhaustion without Covid being the cause and that they were predisposed to getting Covid because of a pre-existing exhaustion. This is like people that ask for HIV inoculation to prove AIDS. Essentially he is just a denialist.
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Anthony Leonardi @fitterhappieraj.bsky.social · 13/04/2025
People who had covid were more likely to be infected with other pathogens subsequently. The T cell damage was evident from the broad activation and differentiation.
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Anthony Leonardi @fitterhappieraj.bsky.social · 13/04/2025
4) A basic scientist would more likely been able to project this, like I had. Nevertheless, bad advice from scientists like Marc facilitated and even encouraged infection and antigenic immune escape, so now we can see the immune response to other pathogens is harmed. thelancet.com/journals/lan...
thelancet.com
Rates of infection with other pathogens after a positive COVID-19 test versus a negative test in US veterans (November, 2021, to December, 2023): a retrospective cohort study
Our results suggest that a positive test for COVID-19 (vs a negative test) was associated with increased rates of diagnosis of various infections in the 12 months following an acute SARS-CoV-2 infecti...
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Anthony Leonardi @fitterhappieraj.bsky.social · 13/04/2025
3) Mechanism includes infection of T cells and broad activation
thelancet.com
Rates of infection with other pathogens after a positive COVID-19 test versus a negative test in US veterans (November, 2021, to December, 2023): a retrospective cohort study
Our results suggest that a positive test for COVID-19 (vs a negative test) was associated with increased rates of diagnosis of various infections in the 12 months following an acute SARS-CoV-2 infecti...
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Anthony Leonardi @fitterhappieraj.bsky.social · 13/04/2025
2) There are papers showing primed T cell apoptosis from sars cov 2, and the infection of T cells by sars cov 2 nature.com/articles/s41... The cd8 response is dulled after infection nih.gov/news-events/...
nature.com
T cell apoptosis characterizes severe Covid-19 disease - Cell Death & Differentiation
Cell Death & Differentiation - T cell apoptosis characterizes severe Covid-19 disease
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Anthony Leonardi @fitterhappieraj.bsky.social · 13/04/2025
Marc uses gish gallop in order to obfuscate the immune harm from covid 1) The phenotypes from infection, broad activation and high differentiation status show there is nonspecific T cell activation This paper shows T cell exhaustion from sars cov 2 to other pathogens insight.jci.org/articles/vie...
insight.jci.org
JCI Insight - PD-1 blockade counteracts post–COVID-19 immune abnormalities and stimulates the anti–SARS-CoV-2 immune response
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