iiinova — where your digital self keeps evolving

Frank Hause @fhause.bsky.social · 02/10/2025

The gentle rays of morning hint at summer’s end.

Foggy morning view of a cable-stayed bridge with a tall central pylon and multiple suspension cables, silhouetted against the rising sun shining through the mist, with tram lines and street lamps in the foreground.

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Frank Hause @fhause.bsky.social · 03/09/2025

What reading through the reviewer comments feels like. #AcademicSky 🧪

A Baroque-style painting showing a man in a brown monastic robe looking upward toward three angels who are holding up a large golden tablet inscribed with ornate sacred letters.

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Frank Hause @fhause.bsky.social · 02/05/2025

Obviously, the system will be there for you—whether you like it or resist it. 🧪 #AcademicSky #PhilSci

Cover of Michel Foucault’s “Power/Knowledge,” featuring a flimsy golden paper crown—symbolizing how authority often masquerades as legitimacy. A book for those who know the system rules you even while you’re critiquing it.

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Frank Hause @fhause.bsky.social · 01/05/2025

The Selfish Gene is full of wild ideas—but strangely, the one about memes replicating like genes might just be the sanest of the bunch. 🧪 #AcademicSky #PhilSci

The cover of The Selfish Gene (40th Anniversary Edition) by Richard Dawkins. Dawkins explores evolution from the gene’s perspective, arguing that natural selection favors genes that maximize their own replication, shaping the behavior of organisms, including altruism, as a strategy for gene survival.

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Frank Hause @fhause.bsky.social · 30/03/2025

In terms of network topology analysis, this weekend has been wildly productive. 🧪 🧬 🖥️ #AcademicSky

Radar plot titled "Metrics for TP53" displaying six centrality-related metrics across twelve biological categories. The metrics—Degree, Betweenness, Closeness, PageRank, Eigenvector, and LFD—are represented by different colored lines. Each axis represents a biological category, and values range from 0% to 100%. Peaks in the plot show how TP53 varies in importance or association across these categories depending on the metric.

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Frank Hause @fhause.bsky.social · 27/03/2025

Sorry, couldn’t resist…

A hand-drawn anime-style illustration inspired by Studio Ghibli shows Angela Merkel with short, light brown hair, wearing a mustard-colored coat with round buttons. She is mid-scream as several colorful parrots—green with red and blue plumage—perch on her arms, shoulders, and a small cup she’s holding. The scene is set in a lush, green aviary-like garden with soft lighting and a glasshouse structure in the background. This whimsical artwork is a reinterpretation of the famous photograph of Merkel at a bird park, where she was hilariously ambushed by parrots while feeding them.

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Frank Hause @fhause.bsky.social · 22/03/2025

Some lovely exhibits at the Mathematical-Physical Cabinet in Dresden 🧪

A clock showing the current time of 360 places on earth

A collection of burning/magnifying glasses

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Frank Hause @fhause.bsky.social · 19/03/2025

This somehow reminds me of a very humble German politician.

Bavarian Minister-President Markus Söder is sitting at a wooden table, wearing a dark suit over a light-colored shirt. He is holding a large chocolate Easter egg decorated with a portrait of himself, smiling in a suit and tie against a green outdoor background.

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Frank Hause @fhause.bsky.social · 19/03/2025

I was never great at math in school or university—but with modern AI and LLMs, I finally have some explanations I need to start approaching complex systems. Today, AI won’t replace a great teacher, but it might just be the tipping point I needed to push further on my own. 🧪 🧬 🖥️ #AcademicSky #PhilSci

$Cover of Nonlinear Dynamics and Chaos by Steven H. Strogatz, Second Edition—an all-time classic in the study of complex systems. The title is displayed in large serif font, with the subtitle ‘With Applications to Physics, Biology, Chemistry, and Engineering’ in smaller blue text. Below, the author’s name is in blue. The cover features a geometric, fractal-like design of interwoven, arrow-shaped patterns in red and gold against a black background, symbolizing complexity and chaos.$

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Frank Hause @fhause.bsky.social · 16/03/2025

Memes don’t just shape culture—they transcend biological systems, influencing evolution itself. Like genes, they might exploit scale-free networks, steering adaptation across neural, social, and even genomic landscapes. Maybe information, not just life, is what evolves. 🧪 🖥️ 🧬 #AcademicSky #PhilSci

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Frank Hause @fhause.bsky.social · 01/03/2025

Triff mich hier, wo ich mich vor den beunruhigenden Nachrichten unserer Zeit verstecke #Anno1800 #Halle

Screenshot aus dem Spiel Anno 1800: Eine Stadtansicht mit symmetrisch angeordneten Wohnhäusern, Straßen und einer zentralen Marktplatzstruktur. Oben im Bild ist eine Benutzeroberfläche mit Ressourcenanzeige und Stadtinformationen zu sehen. Der Stadtname ist 'Halle (Saale)', mit der Beschreibung 'Originelle Hafenstadt' – eine humorvolle Abweichung von der realen Geografie.

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Frank Hause @fhause.bsky.social · 08/02/2025

Visualizing multiple GSEA analyses in one figure is tricky! Here’s my proposal for the problem. Better ideas? 🧪 🧬🖥️ #AcademicSky #MedSky

A heatmap displaying GSEA Normalized Enrichment Scores (NES) for hallmark pathways in proteomics data. The x-axis represents three comparisons: KO vs. WT, RE vs. KO, and RE vs. WT. The y-axis lists hallmark pathways. NES values are color-coded, with pink indicating enrichment (positive NES) and turqoise indicating depletion (negative NES).

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Frank Hause @fhause.bsky.social · 30/01/2025

Maybe gene networks built from paper abstracts via topic modeling are a solid starting point for network topology analysis?! 🧪 #AcademicSky #Bioinformatics

The image contains two bar charts.

Left Chart: Most Frequent Tokens After Preprocessing

This horizontal bar chart displays the most common words (tokens) after text preprocessing, ranked by frequency.
The top words include "gene," "cell," "express," "cancer," "tumor," "regul," "activ," "transcript," and "protein."
The x-axis represents the frequency of token occurrences, while the y-axis lists the tokens.
"Gene" is the most frequent token, followed closely by "cell."
Right Chart: Topic Distribution in Classified Gene Sets

This vertical bar chart presents the number of gene sets classified under different biological topics.
The x-axis represents topics, including "Molecular Oncology & Biomarkers," "Metabolic Regulation," "Apoptosis & Stress Response," "Hematopoiesis & Immune Response," "Tumor Progression & Metastasis," "Stem Cell Differentiation," "Signaling & Growth," "Genomic Alterations & Epigenetics," "Gene Regulation," and "Gene Expression Analysis."
The y-axis shows the number of gene sets per category.
"Molecular Oncology & Biomarkers" has the highest number of gene sets, while "Gene Expression Analysis" has the lowest among the listed topics.
Both charts use blue bars for visualization, with labeled axes and titles.

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Frank Hause @fhause.bsky.social · 18/12/2024

Just finished Uri Alon’s Introduction to Systems Biology—really inspiring for future projects in #omics Modeling and a should-read for anyone working on biological regulatory networks 🧪

Book cover of U. Alon‘s “An Introduction to Systems Biology“

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Frank Hause @fhause.bsky.social · 15/12/2024

Kuhn’s Structure of Scientific Revolutions really shaped how I see science: a journey of paradigms, crises, and chaotic progress. An all-time classic for long winter evenings. 🧪 📖

Book cover of T.S. Kuhn‘s „The Structure of Scientific Revolutions“

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Frank Hause @fhause.bsky.social · 29/11/2024

Feldschlachten nur echt mit Kampfmagiern

Foto vom Mönch von Lützerath, der vor im Schlamm feststeckenden Polizisten steht

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Frank Hause @fhause.bsky.social · 27/11/2024

How do you prefer to receive or share long lists of results, such as enrichment analyses or gene lists? Whether it's in tables, summaries, figures, interactive formats, or something else—what works best for you? #omics #dataanalysis 🧪

Table showing enrichment analysis results with columns labeled as ID, Description, GeneRatio, BgRatio, pvalue, p.adjust, geneID, Ontology, and Module. The table lists biological processes, molecular functions, and pathways with associated statistics such as p-values and adjusted p-values. The table is crowded, dense, and visually overwhelming, making it difficult to comprehend and grasp if many results are presented simultaneously.

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Frank Hause @fhause.bsky.social · 17/11/2024

"completely irrelevant" www.sciencedirect.com/science/arti...

Paragraph from a recent paper: "As strongly requested by the reviewers, here we cite some references [[35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47]] although they are completely irrelevant to the present work."

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Frank Hause @fhause.bsky.social · 02/12/2023

Repost with a pic you have saved that you haven't found a use for

A blue road sign on the border between Spain and Andorra with a circle of yellow stars, reminiscent of the European Union flag, labeled "ANDORRA," suggesting EU membership; however, Andorra is not a member of the EU.

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Frank Hause @fhause.bsky.social · 18/11/2023

eine zigarette kannste dir noch nehm dann is aber genug

Betrügische Sofortnachricht, in der ich als "Mama" angesprochen werde; bevor näher auf das Anliegen eingegangen wird, bitte ich darum, Ordnung in meinem Badezimmer zu schaffen.

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Frank Hause @fhause.bsky.social · 17/11/2023

Bioconductor, eine der weltweit wichtigsten Open-Source-Initiativen der Bioinformatik, gibt heute bekannt, ihre Aktivitäten auf Twitter/X zeitnah einzustellen.

Tweet von Bioconductor: "Bioconductor wird ab dem 17. Dezember 2023 keine Beiträge mehr auf Twitter/X posten. Stattdessen werden wir weiterhin auf anderen sozialen Medien posten, die besser unseren Gemeinschaftsverhaltenskodex widerspiegeln."

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Frank Hause @fhause.bsky.social · 14/11/2023

Traditional German Christmas mood

An elderly lady in a fine black coat with a Spanish flag tied to her back is shouting angrily into the camera.

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Frank Hause @fhause.bsky.social · 11/11/2023

Dabei beweist wenigstens der CEO von OpenAI durchaus einen Sinn für Humor …

Screenshot eines Tweets des OpenAI-CEOs mit einem ChatGPT-Prompt, ein Boomer-GPT zu imitieren. Das Ergebnis in der Preview ist Grok.

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