Reposted by Frédéric Fercoq
Excited to share our latest work lead by Fred Fercoq and Gemma Cairns. Huge thanks to @breastcancernow.bsky.social and amazing colleagues for making it possible. www.cell.com/cell-reports...
cell.com
Integrin-dependent neutrophil slowing reduces lung perfusion and supports metastasis in a model of breast cancer
Fercoq, Cairns, et al. show that mammary tumors induce β2-integrin-dependent neutrophil
slowing in lung capillaries, reducing local perfusion in the pre-metastatic niche.
Restoring integrin activity n...