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Foundation for Applied Molecular Evolution

@ffame.org
30 followers 60 following 29 posts

Interdisciplinary organization led by Dr. Steven Benner combining chemistry, synthetic biology & astrobiology, translating basic research into medical and commercial technologies. Visit our website at ffame.org.

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Foundation for Applied Molecular Evolution @ffame.org · 24/09/2026
Dr. Steven Benner spoke at the College of William and Mary last week about the Viking missions to Mars alongside Gentry Lee, Tom Young, Joel Levine, and others. The Viking missions stands a testament to humanity's ingenuity! Link Below! www.youtube.com/watch?v=FHt7...
youtube.com
The Exploration of Mars and the Search for Life on Mars: Viking to Humans
YouTube video by Live from William & Mary
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Foundation for Applied Molecular Evolution @ffame.org · 18/09/2026
Today at 3 PM EDT, Dr. Steven Benner will give a talk titled: “Why Viking More Likely Than Not Found Life on Mars and Why You Do Not Know That Already” Tune in to the livestream! cdsp.wm.edu/mars-symposi...
cdsp.wm.edu
The Exploration of Mars
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Foundation for Applied Molecular Evolution @ffame.org · 30/07/2026
www.amazon.com/Meet-Neighbo...
amazon.com
Meet the Neighbors: Life on Mars and How to Find It , Benner, Steven A. - Amazon.com
Meet the Neighbors: Life on Mars and How to Find It - Kindle edition by Benner, Steven A.. Download it once and read it on your Kindle device, PC, phones or tablets. Use features like bookmarks, note ...
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Foundation for Applied Molecular Evolution @ffame.org · 30/07/2026
50 yrs ago today, Viking 1 may have found life on Mars! Dr. Benner’s new book "Meet the Neighbors: Life on Mars and How to Find It" tells all. Get your copy now on Amazon!📙 Below is the original respiration data from Viking! 🧪 #Mars #Viking50 #Astrobiology
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Foundation for Applied Molecular Evolution @ffame.org · 09/07/2026
Dr. Steven Benner recently appeared on the Event Horizon podcast to discuss the scientific implications of the 1976 Viking Mars mission, the search for life beyond Earth, and the ideas explored in his upcoming book! Watch it here: www.youtube.com/watch?v=G6h-...
youtube.com
Why Scientists Think NASA Found Life on Mars 50 Years Ago with Dr. Steven Benner
YouTube video by Event Horizon
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Foundation for Applied Molecular Evolution @ffame.org · 12/06/2026
Did NASA Miss Viking’s Discovery of Life on Mars? 🔴 Prof. Avi Loeb's recent article (tinyurl.com/mvn9n7n4), highlights Steven Benner's re-examination of the 1976 Viking mission results. Benner’s new book "Meet the Neighbors" on the topic is out July 23! Pre-order: tinyurl.com/4rcdsc69 #LifeOnMars
tinyurl.com
Did NASA Miss Viking’s Discovery of Life on Mars?
Mainstream scientists warn us about false positives, namely misleading claims for interesting signals that are not substantiated by…
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Foundation for Applied Molecular Evolution @ffame.org · 23/02/2026
Exciting news! We are thrilled to announce that FfAME has been awarded a Space Exploration Science Grant from the Chiwi Foundation (chiwi.ch) to expand our research on the origins of life. We are sincerely grateful to the Chiwi Foundation for its trust and support!
chiwi.ch
The CHiwi Foundation
A Swiss non-profit foundation encouraging research in advanced mathematics, alternative energy, and space exploration. Apply for a grant.
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Reposted by Foundation for Applied Molecular Evolution
Edoardo Gianni @edogia.bsky.social · 13/02/2026
How could a simple self-replicating system emerge at the origins of life? RNA polymerase ribozymes can replicate RNA, but existing ones are so large that their self-replication seems impossible. Could they be smaller? Excited to share our latest work in @science.org on a new small polymerase. 1/n
science.org
A small polymerase ribozyme that can synthesize itself and its complementary strand
The emergence of a chemical system capable of self-replication and evolution is a critical event in the origin of life. RNA polymerase ribozymes can replicate RNA, but their large size and structural ...
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Foundation for Applied Molecular Evolution @ffame.org · 13/01/2026
We've got some non-scientific news! To those looking for laboratory or office space in Alachua, FL, our building has recently had several areas become available. You can check them out at progresscenteralachua.com
progresscenteralachua.com
Home - Progress Center - Progress Park Alachua
Long Term Rentals Choose from our long term rental options that cater space for small organizations as well as large companies. Whether you require dedicated laboratory space or efficient office space...
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Foundation for Applied Molecular Evolution @ffame.org · 05/01/2026
Fresh off the lab press! 🧪🚀📰 50 years after Viking, do we understand the results? A new Astrobiology article published by Benner et al. revisits the Viking mission results, presents a pro-biosignature hypothesis, and revives the belated dialectic. Link below! 🔗 doi.org/10.1177/1531...
doi.org
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Foundation for Applied Molecular Evolution @ffame.org · 16/12/2025
Fresh off the lab press! 📰 Scientists from FfAME, Tohoku Univ., and JAMSTEC report a prebiotic route to form long RNA from compounds containing 1-3 carbon, 0-4 hydrogen and 1-3 nitrogen atoms, in geological environments that occurred on early Earth ~4.3 billion years ago. 🔗 doi.org/10.1073/pnas...
doi.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
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Foundation for Applied Molecular Evolution @ffame.org · 19/11/2025
Here is the recording of the talk "Venus’s Cloud Liquid Is More Light-Absorbing Than Your Blood"!
youtube.com
Venus’s Cloud Liquid Is More Light-Absorbing Than Your Blood
YouTube video by ALFA Mars
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Foundation for Applied Molecular Evolution @ffame.org · 12/11/2025
🚀 Our website just got an upgrade!
Explore our research, meet the team, and see how we’re advancing AEGIS, artificial DNA, and expanding the boundaries of science! 🔬 Check it out → ffame.org 
#FfAME #AEGIS #Research #Astrobiology #Aptamers
ffame.org
FfAME - Foundation for Applied Molecular Evolution
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Foundation for Applied Molecular Evolution @ffame.org · 12/11/2025
Fresh off the lab press! New ACS Chem Bio paper from Benner and colleagues reveals improved Z nucleosides for AEGIS DNA, reducing deprotonation, Z:G mismatches, and boosting fidelity. pubs.acs.org/doi/10.1021/...
pubs.acs.org
Improving the Fidelity of Replication of a Six-Letter DNA Alphabet
The Watson–Crick-Franklin (WCF) rules describing nucleobase pairing in antiparallel strands of DNA and RNA can be exploited to create artificially expanded genetic information systems (AEGIS) with as ...
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Foundation for Applied Molecular Evolution @ffame.org · 03/11/2025
The talk will focus on the recent discoveries made @ffame.org about how organic compounds react in the presence of sulfuric acid and this related astrobiology on Venus! Link below! astro.ufl.edu/colloquia/
astro.ufl.edu
Colloquia
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Foundation for Applied Molecular Evolution @ffame.org · 03/11/2025
Attention Astrobiology and Explorers! Dr. Jan Spacek will be presenting a colloquium this Thursday Nov. 6th from 12:45 to 1:45 pm at the @ufresearch.bsky.social campus in the Bryant Space Science Center in Room 217.
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Foundation for Applied Molecular Evolution @ffame.org · 22/10/2025
This eLetter motivates the long-needed back-and-forth discussion of the astrobiological potential of near-surface Martian soils. This back-and-forth may belatedly undo the damage that this propagation of errors has done to Mars exploration.
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Foundation for Applied Molecular Evolution @ffame.org · 22/10/2025
This misunderstanding of this fundamental detail of Martian near surface geology has damaged efforts to design missions to explore Mars, now for 50 years.
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Foundation for Applied Molecular Evolution @ffame.org · 22/10/2025
A recent and prominent example comes in a NASA-endorsed 2021 "Community Report From the Biosignatures Standards of Evidence Workshop" chaired by Victoria Meadows (University of Washington) and Heather Graham (NASA-GFCS), whose premises included this propagated mistake.
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Foundation for Applied Molecular Evolution @ffame.org · 22/10/2025
Further repetition of these mistakes led to their further amplification and propagation. The compounded mistakes eventually appeared even in leading astrobiology textbooks and NASA-endorsed documents.
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Foundation for Applied Molecular Evolution @ffame.org · 22/10/2025
This evolved into the view that the Martian soil is "self-sterilizing" because it contained a powerful "mystery" oxidant, and therefore could not possibly hold extant Martian life.
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Foundation for Applied Molecular Evolution @ffame.org · 22/10/2025
This mistake published in Science caused multiple generations of astrobiologists to believe incorrectly that the Martian soil contained no organic molecules.
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Foundation for Applied Molecular Evolution @ffame.org · 22/10/2025
The eLetter is appended to the bottom of the Biemann et al. abstract at the link: www.science.org/doi/10.1126/...
science.org
Search for Organic and Volatile Inorganic Compounds in Two Surface Samples from the Chryse Planitia Region of Mars
Two surface samples collected from the Chryse Planitia region of Mars were heated to temperatures up to 500°C, and the volatiles that they evolved were analyzed with a gas chromatograph-mass spectrome...
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Foundation for Applied Molecular Evolution @ffame.org · 22/10/2025
A team of scientists at FfAME (Steve Benner, Jan Spacek, Clay Abraham) joined European astrobiologist Dirk Schulze-Makuch to publish this eLetter in Science that reexamines, at last, a misinterpretation published in Science by Klaus Biemann and his coworkers. Links below!
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Foundation for Applied Molecular Evolution @ffame.org · 16/10/2025
Feel free to follow us to keep up to date with our latest research and scientific contributions!
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Foundation for Applied Molecular Evolution @ffame.org · 16/10/2025
5) Enzymatic synthesis and nanopore sequencing of 12-letter supernumerary DNA www.nature.com/articles/s41... 6) A folding motif formed with an expanded genetic alphabet www.nature.com/articles/s41...
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Foundation for Applied Molecular Evolution @ffame.org · 16/10/2025
3) Artificial Genetic Systems: Self-Avoiding DNA in PCR and Multiplexed PCR doi.org/10.1002/anie... 4) Artificially Expanded Genetic Information Systems for New Aptamer Technologies doi.org/10.3390/biom...
doi.org
Artificial Genetic Systems: Self‐Avoiding DNA in PCR and Multiplexed PCR
Discerning in their choice of partner: The DNA of a self-avoiding molecular-recognition system (SAMRS) binds to natural DNA but not to members of the same SAMRS. Multiplexed PCR with an SAMRS based o...
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Foundation for Applied Molecular Evolution @ffame.org · 16/10/2025
We would like to highlight the following articles as an introduction to our research: 1) Hachimoji DNA and RNA: A genetic system with eight building blocks www.science.org/doi/10.1126/... 2) Catalytic Synthesis of Polyribonucleic Acid on Prebiotic Rock Glasses doi.org/10.1089/ast....
science.org
Hachimoji DNA and RNA: A genetic system with eight building blocks
DNA that includes synthetic bases expands the genetic code from four to eight nucleotide letters
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Foundation for Applied Molecular Evolution @ffame.org · 16/10/2025
FfAME has a long standing history of producing a plethora of outstanding research covering nucleotide chemistry, synthetic biology, origins of life, astrobiology, and diagnostic technologies.
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Foundation for Applied Molecular Evolution @ffame.org · 16/10/2025
Hello Researchers and Science Enthusiasts, We are proud to announce that the Foundation for Applied Molecular Evolution (FfAME) now has a new social media presence!
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