Reposted by Jens ErikssonMaria Letizia Di Martino @mldm.bsky.social · 21/11/2025Thrilled to share that our study on how the pcnB gene sustains Shigella virulence is now published in PLOS Pathogens: journals.plos.org/plospathogen... In short: pcnB ➝increased virulence-plasmid replication ➝ elevated T3SS expression ➝ enhanced invasion/spread within the intestinal epithelium.journals.plos.orgThe pcnB gene sustains Shigella flexneri virulenceAuthor summary Bacterial infections represent a major global threat. Understanding the genetic determinants promoting infections is crucial to overcome this threat. Shigella is an intracellular bacter... 2157
Reposted by Jens ErikssonSellinLab @sellinlab.bsky.social · 24/08/2025Mast cell subsets respond uniquely to Salmonella infection. Read all about it in our latest paper in EJI. Another chapter in our deciphering of mast cell interactions with enterobacteria, driven by Chris von Beek. onlinelibrary.wiley.com/doi/10.1002/...onlinelibrary.wiley.comMast Cell Phenotypic Heterogeneity Impacts the Interplay with Pathogenic Salmonella Typhimurium BacteriaMast cell phenotypic features influence anti-bacterial response. Connective tissue-like mast cells sense Salmonella through combined Toll-like-receptor (TLR) signaling and recognition of Type-III-sec.... 263
Reposted by Jens ErikssonSellinLab @sellinlab.bsky.social · 12/06/2025Our latest work combines human gut epithelial #organoid culture with experimental #Shigella #infections, transposon mutagenesis, and statistical modeling. This has led to the mapping of the comprehensive geneset that drives Shigella epithelial colonization. Out @natgenet.nature.com: rdcu.be/eqGgfrdcu.beA scalable gut epithelial organoid model reveals the genome-wide colonization landscape of a human-adapted pathogenNature Genetics - A genome-wide screen using human gut epithelial organoids combined with transposon-directed insertion sequencing identifies over 100 Shigella flexneri genes required for... 33220
Reposted by Jens ErikssonUnofficial Hackaday Feed @hackaday-feed.bsky.social · 25/11/2024Apollo-era PCB Reverse Engineering to KiCadhackaday.comApollo-era PCB Reverse Engineering to KiCadEarlier this year [Skyhawkson] got ahold of a Apollo-era printed circuit board which he believes was used in a NASA test stand. He took high quality photos of both sides …read more 052
Reposted by Jens ErikssonCuriosity @mcuriosity.bsky.social · 18/11/2024First ever direct image of a multi planet system with a sun-like host star... 1117958459
Jens Eriksson @erixoneriksson.bsky.social · 18/11/2024I made a #ImageJ plugin for exporting hyperstacks as .mp4 for presentations using external #FFMPEG in Windows.github.comImageJ-plugins/FFMPEG_workaround_hack.py at master · Oftatkofta/ImageJ-pluginsImageJ plugins to analyze microscopy data. Contribute to Oftatkofta/ImageJ-plugins development by creating an account on GitHub. 020
