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Eric Surette

@ericsurette.bsky.social

45 followers 60 following 3 posts

Developmental biologist studying multi-tissue coordination of body axis devlopment He/him/his

Posts Replies Media

Reposted by Eric Surette

M. Brent Hawkins @homeobox.bsky.social · 22/06/2026

Excited to share the final published version of our work on the evolution of dorsal-ventral patterning in fins and limbs, now up on @currentbiology.bsky.social In review we added new single LARM element deletions to assess their impact on dorsality. Take a look! 🔬🧪🐟🐁 www.cell.com/current-biol...

A scientific figure showing the phenotypic effects of removing individual enhancer elements from the LARM. On the left side of the image are schematic diagrams of the targeted deletions and on the right are fin skeletons showing altered anatomy.

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Eric Surette @ericsurette.bsky.social · 21/05/2026

Some more of my PhD work is out on preprint! Exciting to share more about the truncate fin phenotype!!

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Reposted by Eric Surette

bioRxiv Developmental Biology @biorxiv-devbio.bsky.social · 20/05/2026

Distinct positional identity at the center of the caudal fin establishes forked shape www.biorxiv.org/content/10.64898/20…

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Reposted by Eric Surette

bioRxiv Developmental Biology @biorxiv-devbio.bsky.social · 23/03/2026

Notch-mediated thyroid hormone regulation of skin development in the zebrafish caudal fin www.biorxiv.org/content/10.64898/20…

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microPublication Biology @micropub7n.bsky.social · 07/02/2026

Increased diameter of arteries and veins in the caudal fins of Danio rerio longfint2 fish is accompanied by fin overgrowth #micropublication #biology #data #caltechlibrary #Zebrafish #PhenotypeData #G micropublication.org/journals/biolo…

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Reposted by Eric Surette

Gabriela Lima @gabrielalima19.bsky.social · 22/01/2026

It’s out! 🐟 We compared three regeneration superstars—axolotl, zebrafish, and Polypterus—to ask how animals regrow limbs and fins. We find shared core processes, and other programs fine-tuned by evolution in surprising, lineage-specific ways. tinyurl.com/mpftkn7y

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Eric Surette @ericsurette.bsky.social · 15/12/2025

Last Friday I successfully defended my PhD thesis! Thank you to all who attended, in person and virtually! Thanks to my partner, family and friends for their endless support, and a thank you especially to my mentor Sarah McMenamin for her guidance and encouragement all these years.

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Reposted by Eric Surette

Parichy Lab | Dave Parichy @dparichy.bsky.social · 19/10/2025

New preprint up with collaborators Jianguo Lu, @mpodobnik.bsky.social, Uwe Irion, Braedan McCluskey, John Postlethwait and others. New Danio genomes, evolution and pigment pattern variation. Long time in the making www.biorxiv.org/content/10.1...

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Benoit Bruneau @benoitbruneau.bsky.social · 26/09/2025

transport yourself to the late 90s with this really cool paper on digit number regulation by Shh and BMP, ZPA and AER. www.pnas.org/doi/10.1073/...

pnas.org

Dual Bmp-negative feedback loops modulate function of both AER and ZPA to buffer and constrain postaxial digit number | PNAS

Several lines of evidence indicate that posterior (postaxial) digit number in tetrapod vertebrates is constrained to the pentadactyl state by inter...

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Aurelie Hintermann @aurhin.bsky.social · 17/09/2025

Are digits modified fins, or evolutionary innovations? Read how we tackled this old question from a new angle🧪 A story with @chasebolt.bsky.social, @homeobox.bsky.social and myself, coordinated by @denisduboule.bsky.social from @college-de-france.fr and published in @nature.com today! #InHoxWeTrust

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PLOS Biology @plosbiology.org · 04/09/2025

What guides fibroblast precursors' migration from the #sclerotome during vertebrate development? @penghuang031.bsky.social &co show that this is driven by #PDGF -mediated chemoattraction, enabling their differentiation into specialized #fibroblast subtypes @plosbiology.org 🧪 plos.io/3HTZ92Y

Top: Transgenic expression of PdgfraΔK-EGFP (cyan) in nkx3.1:Gal4; UAS:NTR-mCherry (magenta) background at 56 hpf. mCherry+ EGFP+ cells are mostly restricted in the dorsal or ventral regions of the trunk. A transverse view of a 50 μm region centered on the dashed line is shown on the right, with the neural tube (nt) and notochord (n) outlined by dotted lines. Bottom: Model for how the migration of sclerotome-derived cells is regulated by chemoattraction mediated by Pdgfab/Pdgfra signaling. (A) In wild-type embryos, nkx3.1+ (cyan) sclerotome-derived cells express the receptor Pdgfra (magenta), while the medial somites express the ligand Pdgfab (orange) in response to Hh signaling. pdgfra+ sclerotome-derived cells undergo extensive migration toward both the notochord in the medial trunk and the fin fold. (B) In pdgfra−/− mutants (pdgframRFP/mRFP and pdgfraref/ref), nkx3.1+ sclerotome-derived cells fail to migrate in any direction and remain in their original location in the ventral and dorsal parts of the somites. (C) In pdgfab−/− embryos, pdgfra+ sclerotome-derived cells fail to migrate toward the notochord, although migration toward the fin fold remains unaffected. (D) In pdgfab−/− embryos with mosaic pdgfab expression, nkx3.1+ sclerotome cells can migrate toward the ectopic pdgfab-expressing cells, either medially around the notochord or ventrally toward the yolk extension. When the pdgfab source is located near or in the notochord, it can completely rescue the migration of nkx3.1+ sclerotome cells toward the notochord. These diagrams depict a 2-somite region located above the yolk extension of a zebrafish embryo at 48 hpf. nt: neural tube; n: notochord.

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Reposted by Eric Surette

M. Brent Hawkins @homeobox.bsky.social · 07/07/2025

We take for granted that our hands have two sides and can articulate in an endless number of ways. But what about a fish’s fin? Can a fish know something “like the back of its fin,” or have its future told with a fin palm reading? Check out this bluetorial to find out 👇🧪🧬🐟 doi.org/10.1101/2025...

Schematics depicting the dorsal and ventral sides of fins and limbs

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Eric Surette @ericsurette.bsky.social · 26/08/2025

Hello Bluesky: Long time listener, first time poster! Excited to share the first publication of my Ph.D. work studying the development of appendage shapes in @plosbiology.org! The zebrafish caudal fin is quite distinctive, and we examine the timing and mechanisms of how its shape might come to be!

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