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Emulate, Inc.

@emulatebio.bsky.social
95 followers 26 following 38 posts

We're empowering a new era of human-centric research and drug development with Organ-on-a-Chip technology. Discover how at emulatebio.com.

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Emulate, Inc. @emulatebio.bsky.social · 18/11/2025
🧠 Learn more in our press release: emulatebio.com/press/emulat... #BrainChip #NeurovascularUnit #Neuroscience #BBB #CNSResearch
emulatebio.com
Emulate Launches Brain-Chip R1 to Advance Neurological Drug Development, in Partnership with FUJIFILM Cellular Dynamics
BOSTON, MA – [Nov 18, 2025] – Emulate, Inc., the leading provider of next-generation Organ-on-a-Chip technology, in partnership with FUJIFILM Cellular Dynamics, Inc., a pioneering global developer and...
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Emulate, Inc. @emulatebio.bsky.social · 18/11/2025
🧪🧠 The first isogenic, five-cell #OrganOnChip model of the human neurovascular unit is now here! Brain-Chip R1 brings together neurons, astrocytes, microglia, pericytes, and BMECs in a dynamic, perfused system that captures key features of the BBB and NVU—built for more predictive CNS research.
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Emulate, Inc. @emulatebio.bsky.social · 23/10/2025
🧪 What if we could predict a patient’s treatment response before they receive it? #OrganonChip technology offers a home away from home for patient-derived samples—revealing how cells truly respond to therapy. Full story 👉 emulatebio.com/using-organ-... #PersonalizedMedicine #PrecisionMedicine
emulatebio.com
Using Organ-on-a-Chip Technology to Unlock Patient-Derived Precision Medicine
Discover how Organ-Chip models using patient-derived samples are advancing personalized medicine — and read three case-studies showing real-world impact in bone-marrow toxicity, neurodegeneration (ALS...
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Emulate, Inc. @emulatebio.bsky.social · 15/10/2025
🔗 Register: emulatebio.com/event/a-new-... #OrganonChip #CancerResearch #PrecisionOncology
emulatebio.com
A New Paradigm for Personalized Cancer Medicine: Predicting Patient-Specific Therapeutic Responses with Organ-on-a-Chip Technology
Personalized medicine has long held the promise of tailoring treatments to the biology of each individual patient. Until now, however, the field has lacked a truly predictive human model. In […]
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Emulate, Inc. @emulatebio.bsky.social · 15/10/2025
🧪A breakthrough for personalized medicine: Patient-derived Organ-Chips can now predict individual responses to cancer therapy — outperforming organoids. Join Dr. Lorenzo Ferri & Dr. Donald Ingber on October 30th for a live webinar exploring this new paradigm in precision oncology. 👇
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Emulate, Inc. @emulatebio.bsky.social · 28/08/2025
Regulators are calling for human-relevant data. 📊 Our CEO Jim Corbett shares how the new AVA™ Emulation System delivers scale + reproducibility for #OrganonChip studies to support FDA submissions and usher in a new era of drug discovery. 👉 Read more: emulatebio.com/insights-int...
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Emulate, Inc. @emulatebio.bsky.social · 15/08/2025
Nominations for the 2026 #LushPrize open Sept 1! In 2024, we won for our landmark Liver-Chip study, proving it can outperform animal tests for predicting DILI & advancing human-relevant science. Who will lead the next leap forward? 🔗 lushprize.org @lushprize.bsky.social #OrganOnChip
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Emulate, Inc. @emulatebio.bsky.social · 06/08/2025
🧪In our latest #blog, we're talking about the key US policy moves that are positioning #OrganonChip and other New Approach Methodologies (NAMs) to become the default alternatives to animal testing in drug development. emulatebio.com/alternatives... #drugdiscovery #sciencepolicy #NAMs
emulatebio.com
A Regulatory Turning Point: A Recent Timeline of U.S. Actions to Reduce and Replace Animal Models in Preclinical Research
Discover how FDA, NIH and Congress are fast tracking alternatives to animal testing—and how Organ on a Chip technology is reshaping drug development.
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Emulate, Inc. @emulatebio.bsky.social · 05/08/2025
This study revealed that cannabinoids have distinct, dose-dependent hepatotoxicity profiles, highlighting the importance of human-relevant models for cannabinoid safety evaluation. Read the full paper here: www.nature.com/articles/s41...
nature.com
Hepatotoxicity evaluation of cannabidiol, cannabinol, cannabichromene and cannabigerol using a human quad culture liver chip - Scientific Reports
Scientific Reports - Hepatotoxicity evaluation of cannabidiol, cannabinol, cannabichromene and cannabigerol using a human quad culture liver chip
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Emulate, Inc. @emulatebio.bsky.social · 05/08/2025
🧪 We’re excited to share the results of a recent collaboration with @herbalifeglobal.bsky.social, now published in Science Reports! Using Emulate’s #organonchip Quad-Culture Liver-Chip S1, this study explored the #hepatotoxicity potential of four common #cannabinoids — CBD, CBG, CBN, and CBC.
Takeaway #1: The Liver-Chip S1 demonstrated differential toxicity profiles of four cannabinoids that traditional animal models could not clearly distinguish.Takeaway #2: The Liver-Chip S1 identified parenchymal cell-specific mechanisms of cannabinoid toxicity--effects that would have been missed by standard monoculture assays.Takeaway #3: The Liver-Chip S1 revealed early inflammatory and functional markers of cannabinoid toxicity, offering insight into potential mechanisms and early warning signs.Takeaway #4: The Liver-Chip S1 modeled dose- and compound-specific hepatotoxicity using clinically relevant exposures of cannabinoids.
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Emulate, Inc. @emulatebio.bsky.social · 24/07/2025
Some examples of the types of lists you can generate include: 🔬 Cancer models of the digestive system 🦠 Infectious disease applications in the lung ☣️ Toxicology studies of the liver 🧫 Microbiome research of the reproductive system Download the digest today to start exploring!
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Emulate, Inc. @emulatebio.bsky.social · 24/07/2025
This digest is also a handy tool for easily compiling a complete list of publications tailored to your organ model and application of interest. Simply set your filter criteria, and the digest will generate a curated list of reference publications for you!
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Emulate, Inc. @emulatebio.bsky.social · 24/07/2025
🧪The newest edition of the Emulate Community Publications Digest is live! We're spotlighting all the recent research from our user community, from patient-matched cancer models to spinal cord chips for modeling sporadic ALS. Download your copy today! emulatebio.com/resources/em... #organonchip
emulatebio.com
Emulate Community Publications Digest: Summer 2025 Issue
With over 120 publications across 30+ organ models, Emulate Organ-Chips are empowering researchers to make game-changing scientific breakthroughs! Download this digest to easily explore all publicatio...
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Emulate, Inc. @emulatebio.bsky.social · 23/07/2025
New blog post alert! If you've heard about "NAMs" but aren't sure what the term means, we've got just the blog for you! Check out our latest post to learn what #NAMs are and how they're driving a new era of human-relevant drug discovery and development! emulatebio.com/new-approach...
emulatebio.com
New Approach Methodologies (NAMs): The Future of Toxicology and Safety Testing
This blog explores the landscape of NAMs, explains how they can be used synergistically, and highlights the key factors driving their recent momentum.
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Emulate, Inc. @emulatebio.bsky.social · 27/06/2025
Built-in incubation, automated imaging, and AI-ready data generation deliver in vivo fidelity at scale. Meet AVA: emulatebio.com/ava
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Emulate, Inc. @emulatebio.bsky.social · 27/06/2025
ICYMI: This month, we heralded in the future of human-centric drug development with the launch of the AVA Emulation System, a first-of-its-kind high-throughput Organ-Chip platform. #organonchip emulatebio.com/press/emulat...
emulatebio.com
Emulate Launches AVA™ Emulation System to Accelerate Drug Development with First-of-its-Kind High-Throughput Organ-Chip Platform
Built-in incubation, automated imaging, and AI-ready data generation deliver in vivo fidelity at scale Boston, MA – Emulate, Inc., the world leader in Organ-on-a-Chip technology, today announced the c...
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Emulate, Inc. @emulatebio.bsky.social · 22/05/2025
🧠 We're only 5 days away from our next webinar! Join us on May 27 as Dr. Clive Svendsen from Cedars-Sinai presents his work using Organ-Chips and iPSCs to model multiple neurological diseases, including ALS, Parkinson’s disease, and FTD. Register now! emulatebio.com/event/using-...
emulatebio.com
Using Organ-on-a-Chip and iPSC Technology to Model Neurological Diseases
Join us on Tuesday, May 27th at 11:30AM EDT (8:30AM PDT / 4:30PM  BST / 5:30PM CEST), where Dr. Clive Svendsen from Cedars-Sinai will discuss how Organ-on-a-Chip technology is enabling […]
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Emulate, Inc. @emulatebio.bsky.social · 15/04/2025
🧪 A new era of drug development: Read our latest press release to learn why we believe the FDA's groundbreaking plan to reduce #animaltesting is a pivotal step forward for patients, researchers, and the entire healthcare ecosystem, and how #organonchip can help. emulatebio.com/press/emulat...
Picture of Emulate's CEO Jim Corbett featuring a quote from the press release
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Emulate, Inc. @emulatebio.bsky.social · 01/04/2025
📢NEW PRODUCT ANNOUNCEMENT 📢 You asked, we listened! Introducing 🥔🫁Organ-Chips 🧠🥔, the perfect lab snack to complement your #OrganOnChip experiments. Take a break from seeding Liver-Chips and feed on some Liver-Chips! Sign up for access today! marketing.emulatebio.com/l/1080863/20...
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Emulate, Inc. @emulatebio.bsky.social · 17/03/2025
So as we all raise a glass (or two!), let’s give a nod to the amazing work our livers do—and the innovative research fueling the next wave of healthcare breakthroughs. Check out our latest White Paper on liver #toxicology to learn more. Sláinte! emulatebio.com/resources/li...
emulatebio.com
Liver Toxicology White Paper: Setting a New Standard in Drug Safety Testing
Discover how the Liver-Chip S1 is transforming drug development and toxicology prediction. This white paper highlights key findings from our 2022 Communications Medicine study, where the Liver-Chip ac...
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Emulate, Inc. @emulatebio.bsky.social · 17/03/2025
Happy #StPatricksDay! While many will be “exercising” their livers today, here at Emulate, we’re celebrating by putting our Liver-Chip to work in the lab! Our #organonchip technology helps researchers better understand liver function and disease, paving the way for more effective treatments.
Cover photo of Emulate's liver toxicology white paper on a background featuring a fluorescence image of hepatocytes on an Organ-Chip.
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Emulate, Inc. @emulatebio.bsky.social · 27/02/2025
They also confirmed that MNP uptake involves both passive diffusion and active endocytosis pathways—suggesting that even “low-toxicity” levels of plastics can still get absorbed and potentially affect gut biology.
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Emulate, Inc. @emulatebio.bsky.social · 27/02/2025
🧪New study using a human Intestine-Chip found that #microplastics / #nanoplastics caused minimal toxicity in both healthy and #Crohn’s small intestinal tissue, but did impact genes linked to immune defense. #OrganOnChip www.sciencedirect.com/science/arti...
sciencedirect.com
Toxicity and absorption of polystyrene micro-nanoplastics in healthy and Crohn’s disease human duodenum-chip models
Micro and nanoplastics (MNPs) are widespread environmental and food web contaminants that are absorbed by the intestine and distributed systemically, …
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Emulate, Inc. @emulatebio.bsky.social · 21/02/2025
Hi Jules, we'd love to be added! We are an Organ-Chip technology provider. Website: emulatebio.com. Here's a link to our seminal paper on how our Liver-Chip model outperforms animals and spheroids for DILI prediction: www.nature.com/articles/s43...
nature.com
Performance assessment and economic analysis of a human Liver-Chip for predictive toxicology - Communications Medicine
Ewart et al. assess the performance of a human Liver-Chip for predictive toxicology. They also perform an economic analysis to demonstrate its potential financial value for the pharmaceutical industry...
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Emulate, Inc. @emulatebio.bsky.social · 19/02/2025
🧪 Predicting which drugs will be toxic to the human liver remains a challenge, in part because 2D cell and animal models are not sensitive enough. This article discusses how complex in vitro models such as #Organ-Chips are changing the safety testing paradigm: www.frontiersin.org/journals/dru...
frontiersin.org
Frontiers | Perspective: How complex in vitro models are addressing the challenges of predicting drug-induced liver injury
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Emulate, Inc. @emulatebio.bsky.social · 14/02/2025
Celebrate the day in style by reading the publication here: pubs.rsc.org/en/content/a... Happy #ValentinesDay and may your monocultures find a friend today!
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Emulate, Inc. @emulatebio.bsky.social · 14/02/2025
Endothelial cells, cardiomyocytes in sync, Predicting drug harm before hearts even blink. Multi-lineage models to catch toxicity’s call, Keeping hearts safe and healthy for all!
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Emulate, Inc. @emulatebio.bsky.social · 14/02/2025
Roses are red, violets are blue, Old heart models lack the punch they once knew. But on an Organ-Chip— #hiPSC so refined— Flow and stretch bring true maturity in kind.
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Emulate, Inc. @emulatebio.bsky.social · 14/02/2025
In the spirit of 🩷 Valentine's Day 🩷 , we've written a little ode to #OrganChips, inspired by the recent Heart-Chip publication from Cedars-Sinai! *Ahem*
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Emulate, Inc. @emulatebio.bsky.social · 03/02/2025
This webinar will explore how the IBD Organ-Chips helped reveal critical insights into the pathogenesis of IBD, including the pivotal role of intestinal stroma and mechanical deformations in driving sex-specific disease progression!
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Emulate, Inc. @emulatebio.bsky.social · 03/02/2025
Join us for a live webinar on Monday, February 24th at 11AM EST to hear Dr. Alican Ozkan from the Wyss Institute share groundbreaking insights into modeling Inflammatory Bowel Disease (IBD) with Organ-on-a-Chip technology. Learn more: emulatebio.com/event/human-...
emulatebio.com
Human Organ-Chips Reveal New Inflammatory Bowel Disease Drivers
Join us on Monday, February 24th at 11AM EST (8AM PST / 4PM  GMT / 5PM CET), where Dr. Alican Ozkan from the Wyss Institute will discuss how he and […]
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Emulate, Inc. @emulatebio.bsky.social · 03/02/2025
An integrated Cervix + Vagina-Chip study shows cervicovaginal mucus plays a protective role against bacterial vaginosis (BV) by reducing inflammation and epithelial damage from dysbiotic microbes, opening new avenues of #research for women’s #reproductivehealth. 🧪 www.nature.com/articles/s44...
nature.com
Cervical mucus in linked human Cervix and Vagina Chips modulates vaginal dysbiosis - npj Women's Health
npj Women's Health - Cervical mucus in linked human Cervix and Vagina Chips modulates vaginal dysbiosis
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Emulate, Inc. @emulatebio.bsky.social · 03/02/2025
Will do, thank you so much!
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Emulate, Inc. @emulatebio.bsky.social · 03/02/2025
Hi Monica, could we please be added? emulatebio.com One of our more recent papers here: www.nature.com/articles/s43...
emulatebio.com
Homepage
Next-generation Organ-on-a-Chip technology allows researchers to emulate biology and predict human response. Get started today.
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Emulate, Inc. @emulatebio.bsky.social · 30/01/2025
How will MPS-based models such as #OrganChips enable breakthrough discoveries in human life sciences? Read the latest t4 workshop report to learn how MPS technology will help drive a new era of human-centric research: pubmed.ncbi.nlm.nih.gov/39827406/
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Emulate, Inc. @emulatebio.bsky.social · 28/01/2025
What makes Organ-Chips such a powerful technology? The ability to faithfully recreate organ-level complexity in an in vitro system. Check out this video showing mucociliary clearance in a Lung-Chip!
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Emulate, Inc. @emulatebio.bsky.social · 28/01/2025
Take a look back with us at the origins of Organ-on-a-Chip technology, as first described in the seminal paper by Dongeun Huh and Donald Ingber, who demonstrated a groundbreaking way to model the alveolar-capillary interface of the human lung: pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov
Reconstituting Organ-Level Lung Functions on a Chip
Here we describe a biomimetic microsystem that reconstitutes the critical functional alveolar-capillary interface of the human lung. This bioinspired microdevice reproduces complex integrated organ-le...
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Emulate, Inc. @emulatebio.bsky.social · 28/01/2025
Hi Bluesky! We’re Emulate—a biotech company that’s focused on creating true-to-life models of human biology that don’t rely on animals. Give us a follow if you enjoy learning about how technology is igniting a new era in human health! #science #research #biology #biotech
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