Pathogene Bakterien schalten ihr Virulenzprogramm erst an, wenn sie sich im Wirt befinden, um nicht frühzeitig vom Immunsystem erkannt zu werden. Forschende haben einen neuen Schalter dafür entdeckt.

Klebsiella pneumoniae is a leading cause of antibiotic-resistant and hospital-acquired infections. The emergence of highly virulent strains of K. pneumoniae capable of causing severe disease is of utm...

npj Vaccines - A multivalent capsule vaccine protects against Klebsiella pneumoniae bloodstream infections in healthy and immunocompromised mice

Klebsiella pneumoniae is a Gram-negative opportunistic pathogen capable of causing a variety of infection types across various hosts. It often causes hospital-acquired invasive infection in immunocomp...

Bacteroides spp. are Gram-negative, gut commensals that shape the enteric landscape by producing outer membrane vesicles (OMVs) that degrade dietary fibers and traffic immunomodulatory biomolecules. U...

Author summary Acinetobacter baumannii causes life-threatening and often antibiotic-resistant infections thereby posing a global threat. Accordingly, there is an urgent need for alternative treatments...

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Author summary Acinetobacter baumannii causes infections that are difficult to treat due to high rates of antibiotic resistance, leading the World Health Organization and CDC to classify this pathogen...