Cardiovascular diseases are the leading cause of global mortality and have been associated with alterations in fetal programming. Maternal hypothyroidism (MH) impairs placental function and induces in...

Clustering and nesting (C&N) arise in many preclinical studies, such as when animals are group-housed or share litters, or in cell culture. Ignoring C&N undermines the validity of analyses. Here, we explain how C&N arise, as well as valid designs and analyses.

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Gestational Diabetes Mellitus (GDM) is a prevalent metabolic disorder during pregnancy, associated with oxidative stress and inflammation at systemic …

This broad group of authors summarizes the impact of circadian factors on metabolic biology and offers recommendations on how to account for and report biological, environmental and experimental factors affecting circadian rhythms in metabolic studies in rodents.

Connecting Researchers Through Bioimaging: Reflections from UCL’s BioImage Interest Group -

Drug Discovery and Development covers strategies and technologies related to pharmaceutical research and development and drug formulation.

Health misinformation (false or misleading data shared unintentionally) and disinformation (deliberately deceptive information) are not new, but the COVID-19 pandemic marked a turning point. The sense...

Hypothyroidism causes ovarian dysfunction and infertility in women and animals and impairs the hypothalamic expression of kisspeptin (Kp). However, kisspeptin is also expressed in the genital system, ...