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@egorlappo.me
127 followers 235 following 15 posts

biology phd student @ stanford | egorlappo.me

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Dmitri Petrov @petrovadmitri.bsky.social · 15/07/2026
Cannot be more excited about the lineup for the inaugural Function of Evolving Systems GRC conference I am co-organizing with the amazing Joy Bergelson. Less than a month away: August 9 - 14, 2026. Still a few spots left! And do check out the amazing list of speakers: www.grc.org/function-of-...
grc.org
2026 Function of Evolving Systems Conference GRC
The 2026 Gordon Research Conference on Function of Evolving Systems will be held in Waterville Valley, New Hampshire. Apply today to reserve your spot.
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егор @egorlappo.me · 13/05/2026
new preprint out! applying the Ewens distribution model to name choices of Catholic Popes (with a neat extension of Slatkin’s exact test to conditional configurations)
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José Aguilar-Rodríguez @jaguilarrod.bsky.social · 22/10/2025
One of the most exciting works of my career, years in the making. We used high-throughput precision genome editing to test the fitness effects of thousands of natural variants. Our findings challenge the long-held assumption that common variants are inconsequential. www.biorxiv.org/content/10.1...
biorxiv.org
Massively parallel interrogation of the fitness of natural variants in ancient signaling pathways reveals pervasive local adaptation
The nature of standing genetic variation remains a central debate in population genetics, with differing perspectives on whether common variants are almost always neutral as suggested by neutral and n...
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егор @egorlappo.me · 21/07/2025
please come see my poster today 🥺🥺🥺 #smbe2025
me with my poster))
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егор @egorlappo.me · 26/06/2025
new preprint from me! did you know that psi index is a hyperbolic tangent of the difference in drift between the two populations?
epsi equation
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Dmitri Petrov @petrovadmitri.bsky.social · 03/06/2025
Flybase lost all of the NIH support overnight - it is a disaster for the community. Please consider donating. I just did! www.philanthropy.cam.ac.uk/give-to-camb...
philanthropy.cam.ac.uk
Drosophila Genetic Database
The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...
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Marianna Karageorgi @mkarag.bsky.social · 22/01/2025
How is functional variation at large-effect loci maintained in natural populations? Thrilled to share our work showing how beneficial dominance reversal helps fruit flies maintain a resistance polymorphism as selection varies in their environment! A thread 🧵 1/n www.biorxiv.org/content/10.1...
biorxiv.org
Dominance reversal maintains large-effect resistance polymorphism in temporally varying environments
A central challenge in evolutionary biology is to uncover mechanisms maintaining functional genetic variation1. Theory suggests that dominance reversal, whereby alleles subject to fluctuating selectio...
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егор @egorlappo.me · 22/01/2025
really happy to have participated in this project! this figure proves that a chromosome-scale sweep happened based on the time series of allele frequencies during the sweep (and even shows loci which have potentially swept independently).
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егор @egorlappo.me · 20/01/2025
new photo posts!! www.lappo.photo
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егор @egorlappo.me · 16/07/2024
did you ever need to run many SLiM simulations to understand the behavior of some popgen quantity? i have released a rust-based wrapper for SLiM that takes care of large-scale parallel runs over parameter grids! github.com/EgorLappo/sl... 1/
github.com
GitHub - EgorLappo/slim-runner: rust-based wrapper for SLiM population genetics simulation engine
rust-based wrapper for SLiM population genetics simulation engine - EgorLappo/slim-runner
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Molly Schumer @mollyschumer.bsky.social · 15/05/2024
Thrilled to share a new lab pre-print from graduate student Tris Dodge! Tris & co elegantly uncover the genetic underpinnings and fitness consequences of a sexual mimicry polymorphism in Xiphophorus birchmanni: www.biorxiv.org/content/10.1...
biorxiv.org
Complex structural variation and behavioral interactions underpin a balanced sexual mimicry polymorphism
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
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егор @egorlappo.me · 08/03/2024
hanging out at #tagc2024
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Maike Morrison @maikemorrison.bsky.social · 05/02/2024
It's conference application season! We in the Rosenberg Lab recently assembled a list of conferences and I thought it could be helpful for other folks doing theoretical population biology. List is below -- feel free to add any we missed!
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егор @egorlappo.me · 15/11/2023
my work on cultural evolution and transmission biases in chess is out today in Proceedings B! royalsocietypublishing.org/doi/10.1098/... humsci.stanford.edu/feature/stud...
humsci.stanford.edu
Study reveals how cultural factors influence chess move choice
A new Stanford study that used population and statistical models to analyze 3.45 million chess games by master players reveals how cultural biases can influence
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егор @egorlappo.me · 25/08/2023
i've been slacking off reading about phylogenetic networks and f-statistics, and instead posted some film photos from my trip to Melbourne egorlappo.me/posts/2023-0...
beach photo on film
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Carl T. Bergstrom @carlbergstrom.com · 20/08/2023
It seems to me that the time is ripe for a Bluesky thread about how—and maybe even why—to befriend crows. (1/n)
Beautiful crow against a black background
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егор @egorlappo.me · 13/08/2023
decided to start posting some of my film photos online! check them out here egorlappo.me/posts/2023-08-12-old-p…
one of my film photos from high school: a house and a very dirty dark sky
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