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ENVLPE, our system for VLP-based delivery of gene editors, is now published in @cellcellpress.bsky.social. We showed efficient delivery of base- and prime-editors in primary T cells & in vivo retinal models. All core constructs are available from @addgene.bsky.social.
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Engineered nucleocytosolic vehicles for loading of programmable editors
Engineered nucleocytosolic vehicles for loading of programmable editors (ENVLPE) with
enhanced CRISPR ribonucleoprotein (RNP) loading and stabilization enable the efficient
delivery of gene-editing ef...