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Earlham Institute

@earlhaminst.bsky.social
2.2K followers 751 following 958 posts

Combining world-class technology and interdisciplinary expertise across genomics, engineering biology and data science to accelerate solutions for health, biodiversity, and food security.  📍 Norwich, UK 🔗 earlham.ac.uk

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Earlham Institute @earlhaminst.bsky.social · 1h
Inspired by the potential of #automation to accelerate synthetic and #engineeringbiology, Davide Annese develops automated workflows helping scientists navigate hurdles of speed, scale, and precision. 👇 okt.to/FLQqnh
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Where biology meets automation: Inside the Earlham Biofoundry
Integrating automation with synthetic biology expertise, Davide Annese in the Earlham Biofoundry. is helping the bioscience community reduce manual labour, speed up process, and increase precision.
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Earlham Institute @earlhaminst.bsky.social · 22h
🆕 Applications are open for a new 3-year Postdoctoral role developing novel computational and mathematical methods to resolve the #genomic diversity of the soil microbiome. 📅 Apply by: 13 November 2026 #soil #microbiome
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(Senior) Postdoctoral Research Scientist
Applications are invited for a three-year position, with a possibility of extension, as a Postdoctoral Research Scientist to join the laboratory of Dr Quince in the High-Resolution Microbiomics group at the Earlham Institute, based in Norwich, UK. Background We are seeking to recruit an individual with a high-level of quantitative skills to develop novel computational and mathematical methods to study the soil microbiome.
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Earlham Institute @earlhaminst.bsky.social · 07/10/2026
📣 Save the date! The Norwich #SingleCell and #Spatial Symposium returns in 2027. Join a supportive forum for researchers working on similar challenges across diverse systems to discuss, network, and share knowledge. 📝 Register your interest to hear more! 🗓️ 22-23 June 2027
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Norwich Single-Cell and Spatial Symposium 2027
Bringing together the international single-cell and spatial community for a two-day discussion across model and non-model systems.
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Earlham Institute @earlhaminst.bsky.social · 06/10/2026
With both pipelines and a Galaxy workflow available, the developers welcome the #scRNAseq and #spatial community to use and test the pipelines, and suggest features to help shape future developments.
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Earlham Institute @earlhaminst.bsky.social · 06/10/2026
A new preprint introduces two standardized, end-to-end pipelines for single-cell RNA-seq and imaging-based #spatialtranscriptomics analysis. EISCA supports droplet- and plate-based scRNA-seq, while EISTA is tailored for high-resolution spatial platforms. #SingleCell #RNAseq
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Preprint: EISCA and EISTA: Full-Spectrum Pipelines for Single-Cell and Spatial Transcriptomics Analysis
Scientists at Earlham Institute, John Innes Centre, University of Freiburgh, and University Medical Center Rotterdam present EISCA and EISTA, two standardized, end-to-end pipelines for single-cell RNA- seq and imaging-based spatial transcriptomics analysis.
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Reposted by Earlham Institute
Gulnara Tagirdzhanova @metalichen.bsky.social · 01/10/2026
Our review on #lichen research in the #omics era is out in @lichenologist.bsky.social! We discuss omics-driven progress and outline several areas and methods that we think especially promising for lichen biology, such as single-cell omics and epigenomics 🖥️ 🧪 🦠 🧫 #SymbioSky doi.org/10.1017/S002...
The infographic is divided into three columns.

Column 1: Sample Types.

At the top is a photo of a yellow Lichen Thallus. An arrow points down to a cross-section diagram showing green algal cells embedded in white fungal hyphae. Below this is Isolate Cultures, showing a petri dish and a test tube containing green liquid.

Column 2: Omics.

- Genomics: Assembly of D N A sequences into complete genomes, illustrated by blue horizontal bars and a double helix icon.

- Transcriptomics: Quantifying expression of genes, shown as small green segments aligning to a dark blue reference genome.

- Metabolomics: Analysis of metabolites, represented by a chemical molecular structure.

- Proteomics: Characterization of proteins, shown as a blue 3 D protein folding model.

- Epigenomics: Exploration of genome modifications, illustrated by blue circles representing histones wrapped in D N A with hexagonal tags.

Column 3: Advances and Opportunities.

- Evolution of lichenization: A phylogenetic tree paired with a horizontal bar chart.

- Gene regulation: A line graph showing chromatin accessibility and a heatmap for motif enrichment analysis. Below is a D N A sequence motif: C G C G A A A A A A.

- Symbiont interaction: A diagram comparing a bulk sample to isolated nuclei using single-cell transcriptomics, visualized with a stacked bar chart showing different cell population proportions.
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Earlham Institute @earlhaminst.bsky.social · 06/10/2026
Later this month, Group Leader Dr @Sarah Guiziou will be at @European Synthetic Biology Society presenting her group's research using recombinase and integrase genetic tools to record gene expression with single-cell resolution and engineer plant development. 🌱🧬 🗓️ Tuesday 20 October
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Biocomputing and Logic Circuits for Sustainable Agriculture with Sarah Guiziou · Luma
Can we program how plants grow? In this talk, Dr. Sarah Guiziou will explore how advanced recombinase and integrase genetic tools let researchers record gene...
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Earlham Institute @earlhaminst.bsky.social · 05/10/2026
💬 “Through COPO we have spent years developing meaningful standards and tooling which properly describe research data. This multiplies its usefulness, making it comparable, reusable and trainable for the community at large." #FAIRdata #ResearchDataManagement #biodiversity
earlham.ac.uk
Accelerating UK biodiversity research with FAIR metadata
The University of Sheffield’s NERC Environmental Omics Facility (NEOF) and Data Science platforms at the Earlham Institute will serve as the backbone data infrastructure for the newly announced Advanc...
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Earlham Institute @earlhaminst.bsky.social · 03/10/2026
With prerequisite materials made available, this course will take you through end-to-end the workflow for generating, processing, and interpreting long-read RNA-seq data - specifically in the context of #singlecell experiments. 🧬💻
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Single-cell Long-read Bioinformatics: from Data Generation to Visualisation
Hands on training in long‑read single‑cell RNA‑seq, from experimental design to data interpretation
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Earlham Institute @earlhaminst.bsky.social · 03/10/2026
Registration closes soon for our hands-on training course in #longread #scRNAseq, covering everything from experimental design to data interpretation with our research faculty. okt.to/Y8HrpT
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Earlham Institute @earlhaminst.bsky.social · 02/10/2026
From scripting robots to troubleshooting experiments, Davide Annese brings together biology and automation expertise at the Earlham #Biofoundry. In a new article find out how automated workflows are helping researchers tackle high-throughput biology. 🧬🤖🔁 #synbio #automation
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Where biology meets automation: Inside the Earlham Biofoundry
Integrating automation with synthetic biology expertise, Davide Annese in the Earlham Biofoundry. is helping the bioscience community reduce manual labour, speed up process, and increase precision.
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Earlham Institute @earlhaminst.bsky.social · 30/09/2026
💬 "The role ARIA has given to data management across this priority area demonstrates how vital FAIR data management is in enabling discovery and innovation." okt.to/elVur2
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Accelerating UK biodiversity research with FAIR metadata
The University of Sheffield's NERC Environmental Omics Facility (NEOF) and Data Science platforms at the Earlham Institute will serve as the backbone data infrastructure for the newly announced Advanced Research and Invention Agency (ARIA) Accelerated Adaptation programme.
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Earlham Institute @earlhaminst.bsky.social · 30/09/2026
'Full-Spectrum Pipelines for Single-Cell and Spatial Transcriptomics Analysis' is now available on bioRxiv, with both pipelines available on GitHub. Read more below 👇 okt.to/Ho3Qac
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Preprint: EISCA and EISTA: Full-Spectrum Pipelines for Single-Cell and Spatial Transcriptomics Analysis
Scientists at Earlham Institute, John Innes Centre, University of Freiburgh, and University Medical Center Rotterdam present EISCA and EISTA, two standardized, end-to-end pipelines for single-cell RNA- seq and imaging-based spatial transcriptomics analysis.
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Earlham Institute @earlhaminst.bsky.social · 30/09/2026
💬 "We invite researchers to try these pipelines on their own single-cell and spatial transcriptomics datasets and encourage users to report issues and suggest feature requests to help shape future developments." - Huihai Wu, Senior Bioinformatician at Earlham Institute.
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Earlham Institute @earlhaminst.bsky.social · 30/09/2026
📃 In a new preprint, scientists introduce two standardized, end-to-end pipelines for single-cell RNA-seq and imaging-based #spatialtranscriptomics analysis. EISCA supports droplet- and plate-based scRNA-seq, while EISTA is tailored for high-resolution spatial platforms. #SingleCell #RNAseq
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Earlham Institute @earlhaminst.bsky.social · 29/09/2026
Join our new training course for hands-on experience in long-read #scRNAseq, covering everything from experimental design to data interpretation with our research faculty. Find out more below ⤵️ #longreads #singlecell #RNAseq
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Single-cell Long-read Bioinformatics: from Data Generation to Visualisation
Hands on training in long‑read single‑cell RNA‑seq, from experimental design to data interpretation
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Earlham Institute @earlhaminst.bsky.social · 29/09/2026
The extraordinary diversity, biology and complexity of #protists pose significant challenges to the #genomics community. A new collaboration will address some of the major technical barriers for sequencing protists from bulk cultures and the environment. 🧬🦠🧪 Read more 👇
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Major investment to unlock the potential of protist research
A new collaboration will tackle major technical challenges currently limiting protist genomics, helping to unlock the potential of protist research for biomanufacturing, sustainable agriculture and environmental applications.
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Earlham Institute @earlhaminst.bsky.social · 28/09/2026
Applications close 01 October for a postdoc in #protist #genomics! This is an exciting opportunity to work on a highly collaborative technical project overcoming barriers in protist sequencing. More details below 👇
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Postdoctoral Research Scientist (Bioinformatics) - Protist Genomics
The Earlham Institute has been awarded funding by the Gordon and Betty Moore Foundation to develop Protist Omics at Scale, a three-year international methods-development programme run in partnership with the Scottish Association for Marine Science, home of the Culture Collection of Algae and Protozoa, and Aalborg University.
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Earlham Institute @earlhaminst.bsky.social · 28/09/2026
💬 "This project lets us apply [these standards] at the pace ARIA requires, so that results from one team can be trusted and reused by the next without starting from scratch." www.earlham.ac.uk/news/acceler... #metadata #FAIRdata #researchdatamanagement
earlham.ac.uk
Accelerating UK biodiversity research with FAIR metadata
The University of Sheffield’s NERC Environmental Omics Facility (NEOF) and Data Science platforms at the Earlham Institute will serve as the backbone data infrastructure for the newly announced Advanc...
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Earlham Institute @earlhaminst.bsky.social · 28/09/2026
🆕 Inspired by the potential of #automation to accelerate synthetic and #engineering biology, Davide Annese develops automated workflows helping scientists navigate hurdles of speed, scale, and precision. 👇 okt.to/qoLEgZ
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Earlham Institute @earlhaminst.bsky.social · 26/09/2026
Drawing on existing knowledge and success stories from the community, researchers are looking to tackle major technical barriers in protist sequencing, including extraction, cell lysis, and DNA amplification methods. 🦠🧬 #protists #sequencing
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Unlocking the potential of protist research
A new collaboration will tackle major technical challenges currently limiting protist genomics, helping to unlock the potential of protist research for biomanufacturing, sustainable agriculture and environmental applications.
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Earlham Institute @earlhaminst.bsky.social · 25/09/2026
Partnering with The University of Sheffield’s @NERC Environmental Omics Facility (NEOF), we'll be developing standards, processes, and tools to underpin #metadata management for ARIA's Accelerated Adaptation programme. 👇 #ResearchDataManagement #FAIRdata
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Accelerating UK biodiversity research with FAIR metadata
The University of Sheffield's NERC Environmental Omics Facility (NEOF) and Data Science platforms at the Earlham Institute will serve as the backbone data infrastructure for the newly announced Advanced Research and Invention Agency (ARIA) Accelerated Adaptation programme.
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Earlham Institute @earlhaminst.bsky.social · 25/09/2026
🧬🥬 From Sequences to Seeds: Collaborative Genomic Innovation in UK Vegetable Breeding Great to see Jamie Pike - Earlham Institute KTP Associate with Tozer Seeds - speaking at the upcoming Sydney Andrew medal lecture with @SCI - Where Science Meets Business. ℹ️ Free to attend, more details below
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Sydney Andrew medal lecture
The SCI Agrisciences Group is delighted to announce that Professor Rosemary Collier from the University of Warwick is the 2026 recipient of the Andrew Medal.
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Earlham Institute @earlhaminst.bsky.social · 24/09/2026
Find out more about gene editing for agriculture below: okt.to/4AJlNx
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How gene editing is bringing healthier, planet-saving foods to your plate
New rules around gene editing have placed England at the forefront of the smart food revolution. This cutting-edge science promises more nutritious, resilient and environmentally friendly crops, and lower costs for farmers.
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Earlham Institute @earlhaminst.bsky.social · 24/09/2026
#PrecisionBreeding offers vital opportunities to transform agriculture and food production. Today's conference is an important opportunity for farmers, breeders, researchers, policymakers, and industry to come together as a community, build connections, and discuss the future landscape.
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Earlham Institute @earlhaminst.bsky.social · 24/09/2026
We're pleased to be at the UK Precision Breeding – Farming Futures Conference today with our colleagues at @John Innes Centre and the #NorwichResearchPark. #UKPB26 #geneediting #agritech
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University of East Anglia (UEA) @uniofeastanglia.bsky.social · 24/09/2026
Researchers from UEA and across Norwich Research Park will help train the next generation of health researchers through new Medical Research Council funding. Read more: bit.ly/4yVb6dE #ResearchMatters #ResearchFunding
Two scientists wearing lab coats and safety goggles work in a laboratory setting, handling glassware and equipment.
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Earlham Institute @earlhaminst.bsky.social · 24/09/2026
Great news for health research in Norwich! New funding from @UK Research and Innovation will support a new MRC Doctoral Landscape Award at UEA in partnership with Earlham Institute, the Norfolk and Norwich University Hospital, @Quadram Institute and @John Innes Centre! #phd
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UEA secures share of £90 million to train next generation of medical researchers
The University of East Anglia (UEA) will help train a new generation of researchers to tackle some of the biggest challenges facing human health - thanks to funding from the Medical Research Council (MRC).
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Earlham Institute @earlhaminst.bsky.social · 23/09/2026
We're recruiting a postdoc in #protist #genomics! This is an exciting opportunity to work on a highly collaborative technical project overcoming barriers in protist sequencing. 🗓️ Apply by: 01 October 2026
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Postdoctoral Research Scientist (Bioinformatics) - Protist Genomics
The Earlham Institute has been awarded funding by the Gordon and Betty Moore Foundation to develop Protist Omics at Scale, a three-year international methods-development programme run in partnership with the Scottish Association for Marine Science, home of the Culture Collection of Algae and Protozoa, and Aalborg University.
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Earlham Institute @earlhaminst.bsky.social · 22/09/2026
💬 “Single-cell genomics is a key technology for recovering the genomic blueprints of these dominant yet elusive eukaryotes, most of which remain uncultured." okt.to/XnUOjt
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Unlocking the potential of protist research
A new collaboration will tackle major technical challenges currently limiting protist genomics, helping to unlock the potential of protist research for biomanufacturing, sustainable agriculture and environmental applications.
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Reposted by Earlham Institute
UK Research and Innovation @ukri.org · 22/09/2026
How can we build a more open, connected and trusted research ecosystem that supports discovery, innovation and impact? From 6-8 October, the Research Data Alliance's @researchdataall.bsky.social 27th Plenary Meeting will explore some of the biggest questions facing the global research community. 1/
Graphic with text that reads:
Research Data Alliance 27th Plenary Meeting (RDA P27). London United Kingdom. 6 - 8 October 2026.
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Earlham Institute @earlhaminst.bsky.social · 22/09/2026
The project will extend Earlham Institute’s data brokering platform - Collaborative OPen Omics, which already has a track record delivering comparable #metadata curation for large international #genomics consortia and cell atlas programmes. #ResearchDataManagement #FAIRdata #metadata
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Earlham Institute @earlhaminst.bsky.social · 22/09/2026
Led by Professor Terry Burke at NEOF, and Dr Felix Shaw at Earlham Institute, the team will build shared data infrastructure including a common data schema and reporting standard, open-source analysis pipelines with dedicated support, and independent verification process to checks results.
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Earlham Institute @earlhaminst.bsky.social · 22/09/2026
We're excited to be partnering with @nerc-eof.bsky.social to provide the backbone data infrastructure for the newly announced @aria-research.bsky.social Accelerated Adaptation programme!
earlham.ac.uk
Accelerating UK biodiversity research with FAIR metadata
The University of Sheffield’s NERC Environmental Omics Facility (NEOF) and Data Science platforms at the Earlham Institute will serve as the backbone data infrastructure for the newly announced Advanc...
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Earlham Institute @earlhaminst.bsky.social · 21/09/2026
Join our new training course for hands-on experience in long-read #scRNAseq, covering everything from experimental design to data interpretation with our research faculty. Find out more below ⤵️ #longreads #singlecell #RNAseq
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Single-cell Long-read Bioinformatics: from Data Generation to Visualisation
Hands on training in long‑read single‑cell RNA‑seq, from experimental design to data interpretation
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Earlham Institute @earlhaminst.bsky.social · 18/09/2026
Drawing on existing knowledge and success stories from the protist community, researchers are set to tackle major technical barriers in protist sequencing, including extraction, cell lysis, and DNA amplification methods. 🦠🧬 #protists #sequencing
okt.to
Major investment to unlock the potential of protist research
A new collaboration will tackle major technical challenges currently limiting protist genomics, helping to unlock the potential of protist research for biomanufacturing, sustainable agriculture and environmental applications.
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Earlham Institute @earlhaminst.bsky.social · 17/09/2026
💬 "We were keen to work with the Earlham Biofoundry because of its expertise in high-throughput strain characterisation and process development." okt.to/Uzkq9H #scaleup #biotech #synbio
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Bridging the scale-up gap for UK engineering biology
As UK startups face a critical scale-up bottleneck, the Earlham Biofoundry is providing the automation, infrastructure and specialist expertise to translate laboratory breakthroughs into commercial-scale biomanufacturing.
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Reposted by Earlham Institute
Knowable Magazine @knowablemag.bsky.social · 19/08/2026
🔬 AI can reduce the development time for new drugs or industrial chemicals from years to months, but the new tech is not without risks. Learn how scientists are working with AI in sophisticated automated laboratories called biofoundries. ✍️ @ben-deighton.bsky.social: knowmag.org/4wz5XpN
knowablemagazine.org
Artificial intelligence boosts automated biolabs
AI and machine learning are kicking synthetic biology up to new levels of innovation. Researchers see huge potential for novel drugs and other chemicals; some also see risks.
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Earlham Institute @earlhaminst.bsky.social · 16/09/2026
💬 “Keep going. Write ugly code, write 100 lines of code that could in fact be 10. Have a go and get it wrong. Start again but from a better educated place each time." For #NationalCodingWeek we've been sharing some top tips from our computational scientists for getting started with coding. 💻🧬
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Curious about coding? 5 tips to get started
From solving biological puzzles to making sense of enormous datasets, coding has become mainstream in modern science. As we generate more data than ever before, the ability to analyse, explore and interpret this treasure trove of information is becoming an essential skill.
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Reposted by Earlham Institute
Sally Warring @sallywarring.bsky.social · 15/09/2026
Come join team Protist at the Earlham Institute!
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Earlham Institute @earlhaminst.bsky.social · 15/09/2026
🆕 Joining a new international project, applications are open for a computational postdoc researcher to work on #protist #genomics. This bioinformatics role focuses on developing and applying novel methods for long-read and #singlecell across a diverse range of protist species.
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Postdoctoral Research Scientist (Bioinformatics) - Protist Genomics
The Earlham Institute has been awarded funding by the Gordon and Betty Moore Foundation to develop Protist Omics at Scale, a three-year international methods-development programme run in partnership with the Scottish Association for Marine Science, home of the Culture Collection of Algae and Protozoa, and Aalborg University.
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Reposted by Earlham Institute
UEA Biological Sciences @biouea.bsky.social · 15/09/2026
Biological Sciences is ranked 58th worldwide in the Research Collaboration Index, the first global ranking dedicated to measuring how effectively universities work with partners around the world. Congratulations to our wonderful and hard-working research staff. #UEAScience
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Earlham Institute @earlhaminst.bsky.social · 15/09/2026
As #NationalCodingWeek encourages people of all ages to develop their digital skills, we asked our computational scientists what coding means to them – and what advice they would give to anyone wanting to start #coding. ⤵️ okt.to/UQJ40p
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Earlham Institute @earlhaminst.bsky.social · 15/09/2026
As we generate more biological data than ever before, the ability to analyse, explore and interpret this treasure trove of information is becoming an essential skill. 💻🧬 But for those new to programming, the prospect of tackling a command line can still feel daunting. #coding #bioinformatics ⤵️
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Earlham Institute @earlhaminst.bsky.social · 14/09/2026
💬 "I contribute to projects across diverse scientific areas – from developing tools to track and study mammalian cells to genetically modifying microbial strains to produce useful compounds. It's a constant learning journey." - Dr Eleonora Tassinari Read more ⤵️ #engbio #synbio
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Bridging the scale-up gap for UK engineering biology
As UK startups face a critical scale-up bottleneck, the Earlham Biofoundry is providing the automation, infrastructure and specialist expertise to translate laboratory breakthroughs into commercial-scale biomanufacturing.
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Earlham Institute @earlhaminst.bsky.social · 14/09/2026
Working on the @BioFAIR Methods Commons, applications are open for a computational workflow expert to join us and deliver expert user support, workflow curation, and training for the @Galaxy Project platform. okt.to/pRTco3
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DevOps Engineer (BioFAIR Methods Commons)
Applications are invited for a DevOps Engineer (BioFAIR Methods Commons) to join the Data Science Group in the Research Faculty of the Earlham Institute, based in Norwich, UK. Background BioFAIR UK is a UK federated digital research infrastructure designed to connect existing services, communities, and expertise to build a cohesive national ecosystem for Findable, Accessible, Interoperable, and Reproducible (FAIR) data.
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Reposted by Earlham Institute
Scottish Association for Marine Science (SAMS) @samsocean.bsky.social · 14/09/2026
The extraordinary diversity, biology and complexity of #protists pose significant challenges to the #genomics community. We're part of a new collaboration addressing some of the major technical barriers for sequencing protists from bulk cultures and the environment.🧪 www.sams.ac.uk/news/sams-ne...
sams.ac.uk
Scientists plan to unlock potential of protists
European centres of expertise to help uncover new applications
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Earlham Institute @earlhaminst.bsky.social · 14/09/2026
💬 "We've made good progress in addressing some of the technical challenges facing the community, but if we don't continue to overcome these bottlenecks and scale these solutions, a vast proportion of biodiversity will continue to be overlooked." - @neilhall.bsky.social, Earlham Institute Director.
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Earlham Institute @earlhaminst.bsky.social · 14/09/2026
Led by the Earlham Institute in Norwich, with @samsocean.bsky.social, the Culture Collection of Algae and Protozoa, and @aau.dk, the project brings together international expertise in #protist culturing, #singlecell genomics, and #longread sequencing. 🧬🦠🔬
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Earlham Institute @earlhaminst.bsky.social · 14/09/2026
The extraordinary diversity, biology and complexity of #protists pose significant challenges to the #genomics community. That’s why a new collaboration will look to address some of the major technical barriers for sequencing protists from bulk cultures and the environment.
earlham.ac.uk
Major investment to unlock the potential of protist research
A new collaboration will tackle major technical challenges currently limiting protist genomics, helping to unlock the potential of protist research for biomanufacturing, sustainable agriculture and en...
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