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eabhorrocks.bsky.social

@eabhorrocks.bsky.social
53 followers 186 following 11 posts
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eabhorrocks.bsky.social @eabhorrocks.bsky.social · 04/07/2026
Free to air in australia too, for the monoglots
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Jonathan Pillow @jpillowtime.bsky.social · 17/12/2025
Bichan Wu (@bichanw.bsky.social) & I wrote a tutorial paper on Reduced Rank Regression (RRR) — the statistical method underlying "communication subspaces" from Semedo et al 2019 — aimed at neuroscientists. arxiv.org/abs/2512.12467
arxiv.org
Reduced rank regression for neural communication: a tutorial for neuroscientists
Reduced rank regression (RRR) is a statistical method for finding a low-dimensional linear mapping between a set of high-dimensional inputs and outputs. In recent years, RRR has found numerous applica...
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Riccardo Storchi @rstorchi.bsky.social · 09/11/2025
Delighted to share our latest preprint. It's been a long time coming. Thanks to all the authors for their unique contribution and for for their patience. We show how the visual thalamus deals with active and passive head motion in freely moving animals: www.biorxiv.org/content/10.1...
biorxiv.org
Efficient mixed representation of active and passive motion in the mouse visual thalamus during natural behaviour
During natural behaviour, changes in the visual scene are largely driven by the subject’s own movements, which can be actively generated (e.g., walking) or passively imposed by external forces (e.g., ...
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Juan Gallego @juangallego.bsky.social · 04/11/2025
🚨Job alert🚨 The lab has up to *3 postdoc openings* for comp systems neuroscientists interested in describing and manipulating neural population dynamics mediating behaviour This is part of a collaborative ARIA grant "4D precision control of cortical dynamics" euraxess.ec.europa.eu/jobs/383909
euraxess.ec.europa.eu
3 Postdoctoral Research Fellows
Champalimaud Foundation (Fundação D. Anna de Sommer Champalimaud e Dr.
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eabhorrocks.bsky.social @eabhorrocks.bsky.social · 06/03/2025
Thanks to our funders and to @alleninstitute.bsky.social for the open-access dataset which allowed us to investigate this question.
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eabhorrocks.bsky.social @eabhorrocks.bsky.social · 06/03/2025
One possibility is that they are specialised for encoding optic flow (see Saleem 2020 www.sciencedirect.com/science/arti...). We discuss other features of AM and PM that suggest their suitability for the encoding of locomotion-related optic flow in the discussion.
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eabhorrocks.bsky.social @eabhorrocks.bsky.social · 06/03/2025
So why are medial HVAs selectively enhanced for visual speed encoding during locomotion?
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eabhorrocks.bsky.social @eabhorrocks.bsky.social · 06/03/2025
Our results therefore reveal how a complex interplay of sensory input and ongoing behaviour differentially shapes the efficacy of sensory processing in mouse HVAs. They also highlight the importance of considering behaviour and context when ascribing functional specialisations to mouse HVAs.
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eabhorrocks.bsky.social @eabhorrocks.bsky.social · 06/03/2025
This selective enhancement of medial HVAs during locomotion wasn’t generic, but specific to visual speed encoding - drifting gratings direction encoding changed non-selectively across mouse visual cortex.
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eabhorrocks.bsky.social @eabhorrocks.bsky.social · 06/03/2025
We were also able to better decode visual speed from population activity in these same areas during locomotion, underlining that the enhancement of visual speed encoding during locomotion is specific to medial HVAs.
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eabhorrocks.bsky.social @eabhorrocks.bsky.social · 06/03/2025
Remarkably, when we compared stationary and locomotion behavioural states we found that locomotion selectively enhanced visual speed tuning in medial HVAs AM and PM, along with V1 and LGN.
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eabhorrocks.bsky.social @eabhorrocks.bsky.social · 06/03/2025
We next focused on how visual speed encoding changes between behavioural states. Previous research has shown that visual feature tuning tends to improve during locomotion in mouse V1, but whether such enhancements occur non-selectively across mouse visual cortex remains poorly understood.
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eabhorrocks.bsky.social @eabhorrocks.bsky.social · 06/03/2025
We focused on how the mouse visual system encodes visual speed and discovered 4 classes of tuning across cortical and thalamic areas. We investigated the properties of these different tuning classes and how they varied between areas.
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eabhorrocks.bsky.social @eabhorrocks.bsky.social · 06/03/2025
Excited to share a new preprint investigating whether functional specialisations of mouse higher visual areas (HVAs) depend on behaviour. With @amansaleem.bsky.social Thread below👇 www.biorxiv.org/content/10.1...
biorxiv.org
Locomotion selectively enhances visual speed encoding in mouse medial higher visual areas
Mammalian visual systems are comprised of multiple brain areas with distinct functional roles. Whilst functional specialisations have been proposed in the mouse based on visual feature encoding, the e...
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Auguste Schulz @auschulz.bsky.social · 03/02/2025
1) Some exciting science in turbulent times: How do mice distinguish self-generated vs. object-generated looming stimuli? Our new study combines VR and neural recordings from superior colliculus (SC) 🧠🐭 to explore this question. Check out our preprint doi.org/10.1101/2024... 🧵
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