iiinova — where your digital self keeps evolving

I was today years old when I found out he was previously married to Kimberly Guilfoyle 20 years ago. He can be a good messenger, but I have no interest in finding out if he's a good person.

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Dysheki @dysheki.bsky.social · 14h

I am (obv) not Jewish and didn't understand the joke without additional background knowledge, but I (obv) love a good dad joke.

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Dysheki @dysheki.bsky.social · 14h

Judges keep fucking around and finding out that presumption of regularity is very difficult to maintain in Trump 2.0.

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Dysheki @dysheki.bsky.social · 18h

Ok, next admin: raid Melania's home looking for immigration paperwork. Yes, I'm that petty. No, I don't care that it would be doing the exact wrong things they did.

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Nick (derogatory) 🎃 @slothropsmap.bsky.social · 11/10/2026

In my mind the defining feature of Trump II is that is ✨actually✨ a kakistocracy. RFK Jr and Russ Vought have very little in common politically, but they do share one essential quality: they are absolutely the worst person alive for the jobs they have.

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Dysheki @dysheki.bsky.social · 11/10/2026

Wait, what? You're allowed to do this in a shootout??? When did that happen?

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Dysheki @dysheki.bsky.social · 11/10/2026

What is up with the decision to have Sid's line out there right now? They've been bodied defensively, so let's have them out there to defend with the goalie pulled, sure.

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Dysheki @dysheki.bsky.social · 10/10/2026

Hockey: the beautiful game.

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Ken Jennings @kenjennings.bsky.social · 07/01/2026

The “prosecute the former regime at every level” candidate has my vote in 2028.

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Dysheki @dysheki.bsky.social · 10/10/2026

What an awful breakdown on that goal.

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Laura Bassett @lebassett.bsky.social · 09/10/2026

“If you don’t like public executions just don’t watch it” says the crowd trying to ban drag shows and books

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Dysheki @dysheki.bsky.social · 06/10/2026

I have a gold standard science experiment to propose . . .

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Colin Williams @colinbwilliams.com · 06/10/2026

INBOX: Allegheny County has a confirmed measles case, an unvaccinated minor. If you shopped at Target on McKnight Rd. on 10/1 between 3:45 and 5:45 p.m., you may have been exposed.

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Dysheki @dysheki.bsky.social · 02/10/2026

(though the two point attempt was dreadful)

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CJ Fogler @cjzero.bsky.social · 01/10/2026

Cam Heyward - Pokémon guy

Cam is wearing a starter jacket that is primarily blue with a front pocket area that says KANTO in large white/red letters and REGION in small ones belowsleeve tops at the shoulders have a yellow stripe at the top with a red one below. The collar is open and zipped down with a yellow section that shows when unzipped

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Dysheki @dysheki.bsky.social · 01/10/2026

There's nothing pro-life about this.

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Angry @angrystaffer.bsky.social · 01/10/2026

You really can’t make this shit up.

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Dysheki @dysheki.bsky.social · 01/10/2026

I wish I knew more about Mike T's gaming habits, it would have been awesome to hear. But holy shit could you imagine the yinzer uproar after every loss? "Too much time in Tomlin City - Mike should not have hobbies and spend every waking moment of every day thinking football".

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Dysheki @dysheki.bsky.social · 01/10/2026

I love that I'm seeing some @bobgrove91.bsky.social posts because now it's time for some hockey 🐧

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Dysheki @dysheki.bsky.social · 29/09/2026

In an 8 team league after 3 weeks, my team leads in total points with 55 more points than the second place team (429 - 374). Yet I'm 1-2 because I hate fantasy football.

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Dysheki @dysheki.bsky.social · 29/09/2026

Get fucked Eric Schmitt (it's so sad how low the bar is for a Senator anymore)

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Prasad Jallepalli, MD, PhD @prasad.bsky.social · 29/09/2026

5 potatoes cubed is still 5 potatoes because potatoes are root vegetables

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Dysheki @dysheki.bsky.social · 27/09/2026

Gonna be tied at half, isn't it? Sigh, lol

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Mike Eliason @holz-bau.bsky.social · 26/09/2026

chat is this good?

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Dysheki @dysheki.bsky.social · 23/09/2026

Had a visitor outside this morning. What's he doing? Wrong answers only edition @jod-33.bsky.social said the squirrel was trying to move the planter. I said they were trying to play hide and seek with someone else.

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Aaron Reichlin-Melnick @reichlinmelnick.bsky.social · 22/09/2026

Okay, this is an incredibly, incredibly cool discovery. The brain stem is a different organ?

The researchers' breakthrough came from studying the earliest moments of embryonic
development, during a stage called gastrulation when the body first takes shape. Jokhai and Dundes discovered that the hindbrain follows a separate developmental path, running in parallel to - rather than branching off from — the pathway that creates the forebrain and midbrain.

The researchers learned this from examining developing mouse embryos. They identified two different brain progenitor cells.
One, which expresses a gene called Otx2, is destined to become the forebrain and midbrain. The other, which expresses a gene called Gbx2, is committed to forming the hindbrain. They showed that these two cell populations never overlap; they are mutually exclusive from the earliest stages of development.

The team then examined the DNA packaging, or chromatin, in these cells. Chromatin is a way cells determine which genes can be easily accessed and which are bundled away out of reach. What they found was striking: The anterior neural ectoderm (future forebrain and midbrain) and posterior neural ectoderm (future hindbrain) have fundamentally different chromatin configurations.
These differences essentially locked each progenitor cell into its respective fate, like travelers on parallel tracks that never cross.

Finally, the researchers looked back over 550 million years of evolutionary time. They found the same two-origin brain pattern in chickens; zebrafish; and,
remarkably, in acorn worms, tiny creatures living on the ocean floor that share a distant common ancestor with humans. Jellyfish, which diverged from humans about 600 to 700 million years ago, have two nervous systems at different ends of their body.
"Our research suggests that evolution took two existing neural systems and pushed them together spatially," Loh said. "Having the brain as one organ would probably be more efficient, but we rely on this primordial way to make the brain as two separate pieces."

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Dysheki @dysheki.bsky.social · 21/09/2026

If you want to feel better about anything, make sure to read about the Beetlejuice show groper lady.

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Dysheki @dysheki.bsky.social · 20/09/2026

And still seeing things.

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Dysheki @dysheki.bsky.social · 20/09/2026

I turned on the game a few minutes late. First play, fumble. You're welcome Steelers nation.

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Dysheki @dysheki.bsky.social · 18/09/2026

Not sure who needs to hear this, but we have soggy bottoms in the near future as a new GBBO starts next week.

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Kelly Knox @kelly-knox.com · 13/09/2026

Detroit Lions LB Derrick Barnes came to the game today in matching Spider-Man suits with his son 😭

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Dysheki @dysheki.bsky.social · 13/09/2026

I guess this is what happens when you become a conspiracy theorist. You see things as they aren't.

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David Ho @davidho.bsky.social · 12/09/2026

I resigned from ExxonMobil today. I spent the last three years doing fossil fuel extraction research at both BP and ExxonMobil. Neither company is acting responsibly. They are racing to maximize extraction while the window to act closes, and gambling with our lives. More below.

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Dysheki @dysheki.bsky.social · 12/09/2026

Found the next ICE employee.

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Dysheki @dysheki.bsky.social · 10/09/2026

Apparently being a consultant means I'm also now a vibe code fixer and I want to punch people.

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Dysheki @dysheki.bsky.social · 09/09/2026

"Thank you Milton Friedman, your legacy is intact." - Nearl, probably

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LifuX @lifux.bsky.social · 08/09/2026

This is why the internet was invented... #LifuX #Dogs #Dogsofbluesky

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Barred and Boujee aka Madiba Dennie @audrelawdamercy.blacksky.app · 07/09/2026

I've been Black long enough to have at least some built-in 'yup, people be racist, and yet we move' defense systems But ngl shit can still sometimes be...jarring! Like seeing this, openly and shamelessly, and knowing Gorsuch had him in his chambers, and that he helps pick federal judges. Sickening!

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Jeremy Berg @jeremymberg.bsky.social · 05/09/2026

New email to Director Bhattacharya to start Labor Day weekend regarding the secret transfer of appropriated funds to the Department of Defense.

Dear Director Bhattacharya:

Nothing screams "radical transparency" like quietly signing an agreement with another agency transferring hundreds of millions of dollars appropriated to NIH that is only publicly disclosed through investigative reporting and only confirmed by a vague statement by you on "X".

As you know, I have been tracking NIH commitments in as close to real time as possible. I am flattered that NIH has mimicked my "funding curves" on the front page of the NIH Reporter website. Apparently, I will need to consider essentially secret interagency transfers in my analysis.

This is another good contribution to your legacy at NIH..."Director Bhattacharya broke new ground and many other things."

Sincerely,

Jeremy M. Berg
Director NIGMS, 2003-2011

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