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Dynamic42

@dynamic42.bsky.social
76 followers 51 following 222 posts

Recreating human physiology in vitro for better therapies and disease research without animal experiments. Posting about news and insights from the organ-on-chip world. Learn more about us here --> dynamic42.com

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Dynamic42 @dynamic42.bsky.social · 06/10/2026
Last chance to join our hands-on organ-on-chip workshop in Sheffield! Meet Japhette and Tim on 12 Oct and explore our platform firsthand.  📍 Sheffield Hallam University  ⏱️ 10:00–15:00 BST Places are limited – secure your slot here: zurl.co/waxTw
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Dynamic42 @dynamic42.bsky.social · 01/10/2026
Preparing organ-on-chip experiments often starts long before cell seeding including steps like sterilization and coating. With our new sterile 2-Channel biochips pre-coated with Collagen I, you can skip these preparation steps and move faster into your experiment.
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Dynamic42 @dynamic42.bsky.social · 29/09/2026
UK is calling 🇬🇧 Join our Organ-on-Chip workshops in Sheffield (12 Oct) or Nottingham (13 Oct) to get hands-on experience with our platform or meet us at ELRIG Drug Discovery 2026 in London, 14–15 Oct, booth C04 to learn how organ-on-chip can improve drug development pipelines.
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Dynamic42 @dynamic42.bsky.social · 28/09/2026
Last week, Marty had the opportunity to showcase our Organ-on-Chip technology at the Organ-on-Chip MasterClass by AZAR Innovations in Utrecht. Our commercial demonstration with hands-on session was filled with plenty of discussion and new opportunities. Thank you for hosting us!
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Dynamic42 @dynamic42.bsky.social · 17/09/2026
Next stop: Graz!  At Myk2026, join us at Booth 6 and learn about our latest work on fungal infection models and antifungal therapies and discover our newest additions to the DynamicOrgan® product series. #organonchip #infection #MYK2026
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Dynamic42 @dynamic42.bsky.social · 16/09/2026
Final day at #EUROTOX2026! Working in toxicology, drug safety or pharmacokinetics and excited about animal-free approaches? Today is the last day to visit us at booth 84. Come by, say hello to our team and find out how our organ-on-chip solutions can support toxicology research.
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Dynamic42 @dynamic42.bsky.social · 11/09/2026
We’re heading to EUROTOX 2026 in Vienna! Meet us at Booth 84 and join Tim’s poster presentation on drug-induced #hepatoxicity in human liver-on-chip models. See our DynamicOrgan® systems plus live TEER & oxygen monitoring demos.  #EUROTOX2026 #toxicity #drugsafety #organonchip
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Dynamic42 @dynamic42.bsky.social · 09/09/2026
When your cells are precious or time-critical, preparation should be predictable. That’s why we are introducing a new version of our classic 2-Channel biochip: sterile and pre-coated with Collagen I, ready for cell seeding directly after arrival.
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Dynamic42 @dynamic42.bsky.social · 08/09/2026
We are delighted to welcome Corinna Schwarz to Dynamic42! Corinna has joined our Production team, bringing valuable hands-on experience in production, quality control and structured operational processes within regulated environments. More here: zurl.co/RoHW5
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Dynamic42 @dynamic42.bsky.social · 03/09/2026
Austria, here we come 🇦🇹  In September, you can meet us at EUROTOX 2026 in Vienna (Booth 84) and Myk2026 in Graz (Booth 6).  Learn more about our #organonchip solutions for #toxicology, #infection modeling #antifungal therapy. #EUROTOX2026 #MYK2026
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Dynamic42 @dynamic42.bsky.social · 25/08/2026
Last week we took a well-deserved break for some team building. We explored a slackline course, cooked over open fire, tried archery & made energy balls. The retreat reminded us how much stronger our work becomes when we communicate clearly & tackle challenges together.
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Dynamic42 @dynamic42.bsky.social · 24/08/2026
Last chance! Our summer sale is ending on 31 August! ☀️ Get our DynamicOrgan® Starter Kits for under €500, including free 2-month Online Academy access. Terms & Conditions apply Learn more here: zurl.co/L3iPU
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Dynamic42 @dynamic42.bsky.social · 19/08/2026
Ready-to-seed - Introducing our new sterile 2-Channel biochips pre-coated with Collagen I. Instead of preparing the biochip yourself, you can start with a sterile, Collagen I-coated chip and focus on what matters most: building your organ model.
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Dynamic42 @dynamic42.bsky.social · 13/08/2026
Our new webshop is live 🚀 Shop our DynamicOrgan® products with product info, specs and order tracking in one place. Registration is available for customers in the EU, except of the regions covered by our distributors. Want to get started? 👉 Simply sign up and start exploring.
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Dynamic42 @dynamic42.bsky.social · 30/07/2026
Summer heat? High. Starter Kit price? Low. ❄️ Get started with DynamicOrgan® Starter Kits for under €500 and receive free 2-month Online Academy access. Valid until 31 Aug 2026. Terms & Conditions apply Learn more here: zurl.co/hcuZ1
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Dynamic42 @dynamic42.bsky.social · 17/07/2026
We are at the JSMC Retreat 2026 in Jena! Meet our colleague Franzi to learn how organ-on-chip technology can support microbiology and infection biology research with human-relevant in vitro models. We’re excited to connect with the JSMC community! #organonchip #infection #jsmc
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Dynamic42 @dynamic42.bsky.social · 16/07/2026
No need to let organ-on-chip adoption make you sweat. ☀️ Our DynamicOrgan® Starter Kits are available for under €500 this summer, including free 2-month Online Academy access. Terms & Conditions apply Learn more here: zurl.co/UsxRX
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Dynamic42 @dynamic42.bsky.social · 09/07/2026
Choosing the right biochip format is an important step when building an organ model. Different research questions require different microenvironments from compartmentalized co-cultures & 3D spheroid models to integrated sensor readouts for barrier integrity or oxygen monitoring.
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Dynamic42 @dynamic42.bsky.social · 30/06/2026
We’re excited to welcome Darlin Lantigua as Dynamic42’s new Field Application Specialist in the United States. We’re strengthening local support for researchers implementing advanced organ-on-chip applications with our DynamicOrgan® platform. More here: zurl.co/p5UHu
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Dynamic42 @dynamic42.bsky.social · 24/06/2026
It’s hot outside — but your lab budget doesn’t have to sweat. ☀️ DynamicOrgan® Starter Kits are available this summer for under €500, including free 2-month Online Academy access. Terms & Conditions apply Learn more here: zurl.co/j3v0G
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Dynamic42 @dynamic42.bsky.social · 18/06/2026
Few days until #EUROoCS2026. Where to find us: 1️⃣ Poster T-126: PDAC-on-chip with T cell modulation 2️⃣ Talk: Real-time O2 + TEER measurement in a gut-on-chip model 3️⃣ Live demo with PyroScience: Come to booth #G3 to see our O₂ sensor system in action.   #organonchip
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Dynamic42 @dynamic42.bsky.social · 17/06/2026
Last call - tomorrow 4 PM CET! Don’t miss “Advanced BBB on Chip Models for Brain Cancer Research” - June 18, 2026 (4 PM CET). Talks + panel on tumor–BBB interactions and drug transport & efficacy testing. Register: zurl.co/FkL3f
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Dynamic42 @dynamic42.bsky.social · 16/06/2026
Some researchers hesitate because they think #OrganOnChip is too complicated. However, as with any new technology, with a step-by-step approach and well-thought-out experimental design, this can soon become a staple method in your lab. Or as Joanna says : "You will be just fine"!
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Dynamic42 @dynamic42.bsky.social · 11/06/2026
1 week left! June 18, 4 PM CET: Advanced BBB on Chip Models for Brain Cancer Research. 🎯 Highlights: • BBB on Chip model setup & optimization • Tumor–BBB interactions (glioma & beyond) • Drug transport & efficacy testing across the BBB Register: zurl.co/cQKad
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Dynamic42 @dynamic42.bsky.social · 10/06/2026
Based in Berlin or nearby? Join us at the Networking Event on Human 3D Organ Models organized by Charité 3R and Einstein Center 3R. Discover our organ-on-chip platform and meet Marty to discuss applications for human-relevant research and 3R-aligned innovation.
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Dynamic42 @dynamic42.bsky.social · 09/06/2026
How do we achieve reproducible TEER measurements? 1️⃣ fixed, planar electrodes for consistent positioning 2️⃣ measurements inside the incubator to minimize temperature variations
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Dynamic42 @dynamic42.bsky.social · 04/06/2026
Oxygen inside chips used to be a black box. Now, integrated optical sensors allow continuous, non-invasive O₂ monitoring under flow. This reveals real time metabolism, drug effects & true physiological conditions. A core biological parameter for in vitro models.
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Dynamic42 @dynamic42.bsky.social · 27/05/2026
How can we build more predictive, human-relevant in vitro models for disease & cancer research? Visit our posters at #MPS2026 today: #Poster 336: Non-invasive #TEER monitoring in a 3D intestine-on-chip model #Poster 369: Micro-vascularized PDAC-on-chip with T cell modulation
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Dynamic42 @dynamic42.bsky.social · 26/05/2026
How much oxygen are cells exposed to inside organ-on-chip models?  Together with PyroScience, we developed the first integrated organ-on-chip platform with non-invasive real-time O₂ sensing. See it live at #MPS2026 📍 Booth 515/517 ☕ Demo schedule: zurl.co/ojj6T
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Dynamic42 @dynamic42.bsky.social · 26/05/2026
We’ve arrived in Washington, DC and can’t wait to see you at #MPS2026! Today: #TEER & #oxygen measurement live with Tom & Amélie Tomorrow: Posters on integrated TEER + PDAC-on-chip Daily: Live oxygen sensor demos at Booth 515/517 with PyroScience Excited to exchange ideas!
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Dynamic42 @dynamic42.bsky.social · 22/05/2026
Beyond endpoint assays: how do you track real tissue dynamics in organ-on-chip systems? Join our educational workshop at #MPS2026 to explore real-time TEER and O₂ monitoring — with hands-on training in biochip handling, seeding, perfusion setup, and live readouts. #TEER #Oxygen
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Dynamic42 @dynamic42.bsky.social · 21/05/2026
Join us June 18, 2026 (4 PM CET) for “Advanced BBB on Chip Models for Brain Cancer Research” with EPO Berlin Buch. Talks + expert panel on tumor, BBB interactions & drug transport/efficacy testing. Register: zurl.co/J6064 #BloodBrainBarrier #OrganOnChip
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Dynamic42 @dynamic42.bsky.social · 19/05/2026
In IBD, loss of butyrate during dysbiosis may weaken mucosal defense against C. albicans. With a Colitis-on-Chip the authors showed butyrate strengthens barrier integrity & boosts macrophage antifungal defense while limiting inflammatory damage. Summary: zurl.co/5F0IS
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Dynamic42 @dynamic42.bsky.social · 13/05/2026
Two weeks until #MPS2026. What you shouldn’t miss: 1️⃣ Educational Workshop: Perform TEER/O₂ live readouts in Dynamic42 biochips 2️⃣ Live demo with PyroScience: Come to booth #515 to see our O₂ sensor system in action. 3️⃣ Posters: TEER for gut-on-chip + PDAC-on-chip
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Dynamic42 @dynamic42.bsky.social · 12/05/2026
What makes the DynamicOrgan® TEER-Sensor Kit different to existing solutions? 👉 Learn more about the DynamicOrgan® TEER-Sensor Kit here: zurl.co/WXXNw #MPS #NAMs #OrganOnChip #DrugDiscovery #NextGenModels #lungonchip #gutonchip #TEER
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Dynamic42 @dynamic42.bsky.social · 11/05/2026
[New Paper] A microbiota-derived metabolite, a human colitis-on-chip, and a new angle on IBD barrier repair. Congratulations to Tim Kaden et al. on this recent publication in Frontiers in Immunology. Read the article here: zurl.co/zSo6m
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Dynamic42 @dynamic42.bsky.social · 29/04/2026
Connect with us at #BioEquity Europe in Prague.  As organ-on-chip technology continues to advance, it is reshaping how complex biological systems are studied. Meet Wolfgang and Knut to discuss how our solutions can improve pre-clinical decision making and accelerate workflows.
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Dynamic42 @dynamic42.bsky.social · 28/04/2026
What equipment is needed to measure TEER inside our organ models? If you are new to organ-on-chip all you need is the DynamicOrgan® TEER-Sensor System Beginner containing: / DynamicOrgan® TEER-Sensor Kit / Peristaltic pump / tighTEER T-31 readout unit + a Computer
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Dynamic42 @dynamic42.bsky.social · 21/04/2026
The complexity of the tumor microenvironment demands in vitro models that truly mirror tumor–stroma crosstalk. Our PDAC model recreates key TME features for confident preclinical drug testing. 👉 Visit us at poster 4923 or booth 536 at #AACR26 🔗 Paper: zurl.co/lYcaC
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Dynamic42 @dynamic42.bsky.social · 21/04/2026
Exploring the role of the blood-brain-barrier in brain cancer research 📹 Watch Amélie introducing our new BBB‑on‑chip model developed with Michelle Zimmer from EPO Berlin-Buch. 👉 We are at #AACR26: Meet us today at Poster 3401 or Booth #536 #CancerOnChip #CancerResearch
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Dynamic42 @dynamic42.bsky.social · 20/04/2026
Great start to #AACR26! Insightful plenaries, great conversations, and an evening reception with @EPO Experimental Pharmacology & Oncology Berlin-Buch GmbH to wrap up the day. Looking forward to many more discussions in the days ahead. 👉 Stop by Booth #536. #CancerOnChip #TME
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Dynamic42 @dynamic42.bsky.social · 14/04/2026
Meet us at #AACR26! 📌 Poster 3401 (Apr 20, 2–5 PM): BBB & glioblastoma on chip model (A. Paillereau) 📌 Poster 4923 (Apr 21, 9–12 PM): Vascularized PDAC on chip model recapitulating immune exclusion (T. Sommermann) 📌 Booth #536:Showcasing our solutions for cancer on chip
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Dynamic42 @dynamic42.bsky.social · 08/04/2026
Closing the gap in brain cancer research. We’re joining forces with EPO Berlin-Buch GmbH to bring human‑relevant organ‑on‑chip models into preclinical research. 🔗 Press release: zurl.co/tWWsk Meet us at #AACR26: Evening Reception (Apr 19 ) & Poster 3401/6 (Apr 20)
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Dynamic42 @dynamic42.bsky.social · 07/04/2026
Most cells in the body never see atmospheric oxygen. 1️⃣ Normoxia = lab air (~21%) 2️⃣ Physioxia = physiological tissue oxygen 3️⃣ Hypoxia = reduced O₂ - key in cancer & chronic disease Knowing the difference matters in every in vitro model. #organonchip #oxygen
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Dynamic42 @dynamic42.bsky.social · 02/04/2026
How does the TEER measurement work inside the DynamicOrgan® TEER-Sensor Biochip? Listen to Tim explain the technology behind our newest Kit in the DynamicOrgan® Product family.
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Dynamic42 @dynamic42.bsky.social · 31/03/2026
How do scientists assess the integrity of cellular barriers? TEER assays! TEER quantifies the barrier integrity by measuring electrical resistance across them. Values are highest in a cell layer with maximum confluence and decrease upon disturbance or damage to the barrier.
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Dynamic42 @dynamic42.bsky.social · 30/03/2026
Proud to support the #organonchip and #NAMs community at 3R LÄND! Congrats to Seán Scanlon Boyle, winner of the poster prize for his outstanding work on porcine ex vivo eye models. Inspiring work from the next generation of scientists!
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Dynamic42 @dynamic42.bsky.social · 26/03/2026
Do you think that organ-on-chip technology offers fewer analysis options than conventional in vitro models? In fact, all methods such as supernatant assays, PCR, imaging or tissue rescue can be performed in exactly the same way as in standard cell cultures. #organonchip
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Dynamic42 @dynamic42.bsky.social · 25/03/2026
Advanced organ on chip models need real insight into oxygen levels and barrier function – and our new real-time TEER and oxygen measurement solutions enable exactly that. See it live at the 3R Conference hosted by 3R Center Tübingen.  👉Join us at booth 8 for a live demo.
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Dynamic42 @dynamic42.bsky.social · 24/03/2026
At #2026SOT? Join our exhibitor-hosted session for a live demo of #TEER and #oxygen measurement using our new DynamicOrgan® Sensor Kits and discover how they enhance barrier integrity assessment in predictive toxicology. 📅 Mar 25, 10:45–11:45 📍 Room 24A See you tomorrow!
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