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Dustin Updike

@dustinupdike.bsky.social
440 followers 390 following 17 posts

Associate Prof, MDIBL | C. elegans germ granules | Hiding in the woods of Maine

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Dustin Updike @dustinupdike.bsky.social · 27/02/2026
So proud to see this guest essay in the NYTimes from @sciencewhizliz.bsky.social on growing up unvaccinated and what it taught her about science and trust. Liz was a postdoc with us ('16-'20) and is an exceptional science communicator. Also, her old desk is empty - open postdoc position (pls share).
nytimes.com
Opinion | I’m an Immunologist. I Grew Up Unvaccinated.
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Navin B. Ramakrishna @navinbr.bsky.social · 15/09/2025
Schematics of our increasing knowledge of in vivo human primordial germ cell development, and a summary of the exciting hPGCLC maturation protocols: @dev-journal.bsky.social @biologists.bsky.social
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Dustin Updike @dustinupdike.bsky.social · 02/07/2025
C. elegans, ba ba ba. #Worm25
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Dustin Updike @dustinupdike.bsky.social · 30/06/2025
Two cancelled flights, ten delays, and a 36-hour odyssey past Polyphemous, Scylla, Charybdis, and the Laestrygonians—but we finally made it to #Worm25!
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Dustin Updike @dustinupdike.bsky.social · 28/06/2025
Ah, the joys of traveling anywhere from downeast Maine - our flight out of Bangor to #Worm25 was cancelled. Delayed, but not deterred - we'll see all you worm folk tomorrow.
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Dustin Updike @dustinupdike.bsky.social · 08/05/2025
Part of the puzzle unlocked. Excellent work from the Phillips and Montgomery labs.
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Coleen Murphy @ctmurphy1.bsky.social · 23/04/2025
🧪#Celegans - I am very excited to announce the publication of our latest finding in transgenerational epigenetic inheritance (TEI) of learned pathogen avoidance - • C. elegans transgenerational avoidance of P. fluorescens is mediated by the Pfs1 sRNA and vab-1 www.science.org/doi/10.1126/...
science.org
C. elegans transgenerational avoidance of P. fluorescens is mediated by the Pfs1 sRNA and vab-1
C. elegans’ TEI of learned pathogen avoidance is induced by a third bacterial small RNA, Pfs1, from P. fluorescens 15.
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Colin Conine @colinconine.bsky.social · 16/04/2025
The first C. elegans paper from lab! We find that, similar to mammals, tRNA-fragments (or the new name in the field tDRs) accumulate in worm sperm and can transmit non-genetically inherited phenotypes to offspring. We also find an RNase that regulates their processing, showing that length matters
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MDI Biological Laboratory @mdibl.org · 07/03/2025
Science thrives because of our dedicated researchers, students, supporters, and community members. At MDI Bio Lab, we believe in the power of discovery, education, and collaboration. Thank you for #standupforscience2025, believing in science, and being part of our community! #standwithscience 🧪 🤝
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Dr. Michael D. L. Johnson @copperbae.bsky.social · 22/02/2025
Funding science is like betting on horses. Only with science, for each dollar you bet on a horse, you average getting two to three dollars in winnings. Also, you can bet on more than one horse in the field. Plus you learn something that up to that moment, no one knew before.
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Oded Rechavi @odedrechavi.bsky.social · 18/02/2025
What an amazing discovery from Scott Kennedy's lab! A new splicing system that recognizes transposons and removes them from mRNAs! t.co/3p3wyxkYXX
t.co
https://www.biorxiv.org/content/10.1101/2025.02.14.638102v1?ct=
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Derek Lowe @dereklowe.bsky.social · 02/12/2024
Fluorescently labeled proteins are essential to research. But we should never forget how messed-up their behavior can be. An example from condensates:
science.org
Fluorescent Tags Are Basically Never Silent
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Dustin Updike @dustinupdike.bsky.social · 21/11/2024
For you or someone you know? I have to say, it's pretty great up here.
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Abby Dernburg @adernburg.bsky.social · 21/11/2024
Ru-upping this thread from last year since the paper is now out! @chenshuliu.bsky.social identified a Piezo-dependent mechanism that enables C. elegans to sniff out “bad eggs” and target them for destruction. www.science.org/doi/10.1126/...
science.org
Chemically induced proximity reveals a Piezo-dependent meiotic checkpoint at the oocyte nuclear envelope
Sexual reproduction relies on robust quality control during meiosis. Assembly of the synaptonemal complex between homologous chromosomes (synapsis) regulates meiotic recombination and is crucial for a...
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